DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20160053

Heart failure as the initial manifestation of takayasu’s arteritis

Mohd Amir Khan, Santwana Dinesh Chandrakar, Varun Shetty

Abstract


Takayasu’s arteritis is a rare systemic, inflammatory large vessel vasculitis of unknown etiology that most commonly affects women of childbearing age. It is defined as granulomatous inflammation of the aorta and its major branches. We describe a 27 years old female who presented with dyspnea in the emergency medicine department of DY patil hospital, Maharashtra, India. The initial examination showed signs of heart failure along with unequal pulses bilaterally with difference in systolic BP in bilateral upper limb of more than 10 mm Hg. Patient underwent routine investigations like ECG / 2D-echo / cardiac markers. 2decho was suggestive of severe pulmonary hypertension with dilated cardiomyopathy. Further investigation in view of physical findings and 2decho report led to the diagnosis of takayasu’s arteritis.


Keywords


Takayasu’s arteritis, Heart failure, Aortogram, Pulseless disease, Steroids

Full Text:

PDF

References


Jennette JC, Falk RJ, Andrassy K, Bacon PA, Churg J, Gross WL. Nomenclature of systemic vasculitides. Proposal of an international consensus conference. Arthritis Rheum. 1994;37(2);187-92.

Arend WP, Michel BA, Bloch DA, Hunder GG, Calabrese LH, Edworthy SM et al. The American Collegeof Rheumatology 1990 criteria for the classification of Takayasu arteritis. Arthritis Rheum. 1990;33(8):1129-34.

Aggarwal A, Chag M, Sinha N, Naik S. Takayasu’s arteritis: role of mycobacterium tuberculosis and its 65 kDa heat shock protein. Int J Caridol. 1996;55(1):49-55.

Yagi K, Kobayashi J, Yasue S, Yamaguchi M, Shiobara S, Mabuchi H. Four unrelated cases with Takayassu arteritis and CD36 deificiency; possible link between these disorders. J Intern Med. 2004;255(6);688-9.

Salvarani C, Magnai L, Catanoso M, Pipitone N, Versari A, Dardani L et al. Toclizumab; a novel therapy for patients with large-vessel vasculitis. Rheumatology (Oxford). 2012;51(1);151-6.

Unizony S, Stone JH, Stone JR. New treatment strategies in large vessel vasculitis. Curr Opin Rheumatol. 2013;25(1):3-9.

Maksimowicz-McKinnon K, Hoffman GS. Takayasu arteritis: what is the long-term prognosis? Rheum Dis Clin North Am. 2007;33(4):777-86.