Published: 2018-05-25

Prevalence of psychiatric co morbidities in bronchial asthma and chronic obstructive pulmonary disease patients in north Indian population cohort

Vineet Mahajan, Himanshu Sareen, Surya Kant, Jyoti Bajpai, Apoorva Narain, Sandeep Soni, B. K. Kapoor


Background: Psychiatric co morbidities tend to occur quite frequently in patients of chronic respiratory diseases mainly bronchial asthma and Chronic Obstructive Pulmonary Disease (COPD) but still it is highly under diagnosed. Aim and objective of the study was to find out the prevalence of psychiatric co morbidities in asthma and COPD and to correlate them with disease severity according to Global Initiative against Obstructive Lung Disease (GOLD) and Global Initiative against Asthma (GINA) guidelines.

Methods: Study was conducted in Department of TB and Chest in association with Department of Psychiatry of Punjab Institute of Medical Sciences, a secondary care medical college in north India. A total 204 patients, 68 of bronchial asthma, 68 0f COPD and 68 were controls included in the study. Diagnosis and severity of respiratory diseases was assessed by spirometry. Evaluation of psychiatric co morbidities was done using the MINI international neuropsychiatric interview questionnaire.

Results: The frequency of psychiatric co morbidities in COPD patients was significantly higher (32.4%) compared to patients of bronchial asthma (20.6%). The most common co morbidity in both arms was generalized anxiety disorder (17.6% in COPD patients and 10.3% in patients of bronchial asthma.

Conclusions: COPD patients have a higher frequency of psychiatric co morbidities compared to bronchial asthma patients and control population. These should be properly screened and treated.



Anxiety disorder, Bronchial asthma, COPD, Spirometry

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Asnaashari AM, Talaei A, Haghighi MB. Evaluation of psychological status in patients of asthma and COPD. Iran J Allergy Asthma Immunol. 2012;11:65-71.

Norwood R. Prevalence and impact of depression in chronic obstructive pulmonary disease patients. Curr Opin Pulm Med. 2006;12:113-7.

Bratek A, Zawada K, Beil- Gawelczyk J, Beil S, Sozanska E, Krysta K, et al. Depressiveness, symptoms of anxiety and cognitive dysfunctions in patients with asthma and chronic obstructive pulmonary disease (COPD): possible associations with inflammation markers: a pilot study. J Neural Transm. 2015;122:S83-S89.

Putman-Casdorph H, Mc Crone S. Chronic obstructive pulmonary disease, anxiety, and depression: state of the science. Heart Lung. 2009;38:34-47.

Chaudhary SC, Nanda S, Tripathi A, Sawlani KK, Gupta KK, Himanshu D, et al. Prevalence of psychiatric co morbidities in chronic obstructive pulmonary disease patients. Lung India. 2016;33:174-8.

Bhaskar M, Sarawag M, Mathai PJ. Psychiatric morbidity in patients with COPD and bronchial asthma: a comparative study. Int J Health Sci Res. 2015;5:106-12.

Kunik ME, Roundy K, Veazey C, Souchek J, Richardson P, Wray NP, et al. Surprisingly high prevalence of anxiety and depression in chronic breathing disorders. Chest. 2005;127:1205-11.

Sharma BB, Singh S, Sharma VK, Choudhary M, Singh V, Lane S, et al. Psychiatric morbidity in chronic respiratory disorders in an Indian service using GMHAT/PC. Gen Hosp Psychiatry. 2013;35:39-44.

Kahraman H, Orhan FO, Sucakli MH, Ozer A, Koksal N, Sen B. Temperament and character profiles of male COPD patients. J Thorac Dis. 2013;5:406-13.

Brenes GA. Anxiety and chronic obstructive pulmonary disease: prevalence, impact and treatment. Psychosom Med. 2003;65:963-70.

Gania AM, Nabij J, Malik JA, Khan AW. Psychiatric co morbidities in patients of COPD and bronchial asthma attending OPD of tertiary care hospital. J Evolution Med Dent Sci. 2016;5:920-4.

Vogele C, Leupoldt AV. Mental disorders in chronic obstructive pulmonary disease (COPD). Respiratory Medicine. 2008;102:764-73.