Study of pulmonary tuberculosis in diabetes mellitus

Vinay Kumar A., Raj Kumar K., Nithin Kumar Reddy R.


Background: To study the clinical profile of pulmonary tuberculosis in diabetic patients and to study the radiographic patterns of pulmonary tuberculosis in diabetic patients.

Methods: The study was undertaken on 100 patients with diabetes mellitus and pulmonary tuberculosis of both sexes admitted to Chalmeda Anand Rao Institute of Medical Sciences, Bommakal, Karimnagar.

Results: The fasting blood sugar value showed a definite co-relation with pulmonary tuberculosis. 41% of the patients had fasting blood sugar value between 201 to 300mg/dl and 30% had value between 151-200mg/dl and 23% of the patients had value above 300mg/dl. Mean fasting blood sugar value was 234.4mg/dl. Right sided lung lesions were noted in 37% of the cases and left sided lesions in 33% of the cases. Upper lobe lesions were noted in 68% of the cases and bilateral lesion in 30% of the study group.

Conclusions: Uncontrolled diabetes mellitus patients are more prone to develop pulmonary tuberculosis compared to non diabetics. Sputum examination tends to be positive in diabetics compared to non diabetics.


Diabetes mellitus, Fasting blood sugar, Pulmonary tuberculosis, Post prandial blood sugar, Sputum examination

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World Health Organization. Tuberculosis Fact Sheet. Fact Sheet No.104. 2007. Available at html. Accessed 25 September 2007.

World Health Organization. Diabetes fact sheet No. 312. 2006. Available at: mediacentre/factsheets/fs312/en/index.html. Accessed 12 March 2008.

Jeon CY, Murray MB. Diabetes mellitus increases the risk of active tuberculosis: a systematic review of 13 observational studies. PLoS medicine. 2008 Jul 15;5(7):e152.

Vishwanath R. History of tuberculosis. In: Rao KN, Vishwanath R, Deshmukh MD, editors. Textbook of tuberculosis. 2nd edition Vikas publishing house; 1981:2-3.

Davies PDO, Girling DJ, Grange JM. Tuberculosis and its problems in developing countries. In: Weatheral DJ, Ledingham GG, Warell, editors. Oxford Textbook of Medicine. Oxford University Press;1996;3:638.

Deshmukh PA, Shaw T. Pulmonary tuberculosis and diabetes mellitus. Ind J Tub. 1984;31:114.

Patel JC, Desouza, Cheryl, Jigjini SS. Diabetes and tuberculosis. Ind J Tub. 1977;24:155-8.

Morris JT, Seaworth BJ, McAllister CK. Pulmonary tuberculosis in diabetics. Chest. 1992;102:539-41.

Tripathy SR, Kar KP, Chakraborthy DC, Majumdar AK. Diabetes mellitus and pulmonary tuberculosis- A prospective study. Ind J Tub. 1984;31:122.

Feza B, Ozen KB, Gursel C, Abdullah S, Mahmut A. Pulmonary tuberculosis in patients with diabetes mellitus. Respiration. 2001;68:595-600.

Nihalani KD, Menon P. Diabetes association with pulmonary tuberculosis. J Diabetes Assoc India. 1978;18:79.

Anand AL. Pulmonary tuberculosis and diabetes mellitus-radiological consideration. Ind J Tub. 1984;31:91.

Sachdeva AK, Arora RC, Misra DN. Clinicoradiological study of pulmonary tuberculosis in diabetics. J Assoc Physicians India. 1984;32:30.

Oluboyo PO, Erasmus RT. The significance of glucose intolerance in pulmonary tuberculosis. Tubercle. 1990 Jun 1;71(2):135-8.

Banerjee S, Banerjee M. Diabetes and tuberculosis interface. J Indian Med Assoc. 2005;103:318-22.

Bacakoglu F, Basoglu O, Cok G, Sayiner A, Ates M. Pulmonary tuberculosis in patients with diabetes mellitus. Respiration. 2001;68(6):595-600.

Perez GC, Torres CA, Villarreal VH, Vargas MH. Progressive age-related changes in pulmonary tuberculosis images and the effect of diabetes. Am J Respir Crit Care Med. 2000;162(5):1738-40.

Ravindran P, Joshi M, Sundaram P, Joseraj R, Parameshwaran K. Lower lung field tuberculosis. Ind J Tub. 1992;39:29.