Association between vitamin D status and obesity in Bulgarian pre-pubertal children: a pilot study

Authors

  • Bistra T. Galunska Department of Biochemistry, Molecular medicine and Nutrigenomics, Medical University of Varna
  • Daniela I. Gerova Department of General Medicine and Clinical Laboratory, Medical University of Varna
  • Sonya V. Galcheva Department of Pediatrics, Medical University of Varna
  • Violeta M. Iotova Department of Pediatrics, Medical University of Varna

DOI:

https://doi.org/10.18203/2320-6012.ijrms20160284

Keywords:

25-hydroxyvitamin D, Pre-pubertal children, Obesity, Insulin resistance

Abstract

Background: It is considered that obesity and metabolic syndrome are accompanied with vitamin D deficiency. We aimed to examine the interrelations between vitamin D status and biomarkers for metabolic syndrome in Bulgarian pre-pubertal children.

Methods: The study enrolled 51 pre-pubertal children (29 boys, 22 girls) examined for serum 25-xydroxyvitamin D, and routine parameters for metabolic syndrome. Obesity was evaluated by body mass index and waist circumference.

Results: More than half (57.1%) of the studied children were vitamin D deficient, prevalent in girls than in boys (65.0% vs. 51.7% respectively). A tendency for worse metabolic status in the vitamin D-deficient group, expressed by higher fasting insulin, total cholesterol, total cholesterol/HDL-ratio and Homeostasis Model Assessment (HOMA)-index was observed. A trend for negative correlation was established between 25-xydroxyvitamin D and waist circumference, HOMA-index, and fasting insulin.

Conclusions: Vitamin D deficiency and inverse relationships between 25-xydroxyvitamin D and waist circumference, HOMA-index, and insulin were found amongst studied children.

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Published

2016-12-25

How to Cite

Galunska, B. T., Gerova, D. I., Galcheva, S. V., & Iotova, V. M. (2016). Association between vitamin D status and obesity in Bulgarian pre-pubertal children: a pilot study. International Journal of Research in Medical Sciences, 4(2), 361–368. https://doi.org/10.18203/2320-6012.ijrms20160284

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Original Research Articles