A rare case of fungal meningitis with atypical presentation in immunocompetent patient

Authors

  • Rajnish Kumar Department of Internal Medicine, Suryadeep Hospital, Gurugram, Haryana, India
  • Priyanka . Department of Ophthalmology, Suryadeep Hospital, Gurugram, Haryana, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20182854

Keywords:

Atypical presentation, Antifungal therapy, Altered mental status, HIV/AIDS, Lumbar puncture

Abstract

Fungal meningis is uncommon in general population especially in immunocompetent indivisuals. Meningitis, when caused by the fungal mycoses Cryptococcus neoformans, is normally seen in immunocompromised hosts. However, it is also seen in immunocompetent patients. In patients with an intact immune system, CM usually presents with the typical signs and symptoms of meningitis: fever, stiff neck, dizziness and headache. We report a rare case of fungal meningitis in a immunocompetent patient on antiseizure drugs for last 12 years misdiagnosed as phynetoin toxicity.

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References

Thompson HI. Not your typical patient: cryptococcal meningitis in an immunocompetent patient. J neuroscience nursing: J American Association of Neuroscience Nurses. 2005 Jun;37(3):144.

O’Meara TR, Alspaugh JA. The Cryptococcus neoformans capsule: a sword and a shield. Clin Microbiol Rev. 2012;25:387-408.

Louro R, Ferreira R, Pinheiro C, Parada H, Faria D, Monteiro E. Fungal meningitis in an im-munocompetent patient. Clin Drug Investig. 2013;33 Suppl 1: S47-50.

Ones GA, Nathwani D. Cryptococcal meningitis. British J Hospital Med.1995;54:439-45.

Mitchell DH, Sorrell TC, Allworth AM, Heath CH, McGregor AR, Papanaoum K, et al. Cryptococcal disease of the CNS in immunocompetent hosts: Influence of cryptococcal variety on clinical manifestations and outcome. Clinical Infectious Diseases. 1995;20:611-6.

Speed B, Dunt D. Clinical and host differences between infections with the two varieties of Cryptococcus neoformans. Clinical Infectious Diseases. 1995;21:28-34.

Turner G, Scaravilli F. Parasitic and fungal disease. In: Graham DI, Lantos DL, editors.Greenfield's neuropathology.7th ed. Arnold; London: 2002:107-50.

Vandemark MV, Lovasik DA, Neatherlin JS, Omert T. Infectious and autoimmune processes. In: Bader MK, Littlejohns LR, editors. AANN's core curriculum for neuroscience nursing. 4th ed. Saunders; St. Louis, MO;2004:619-680.

Perfect JR, Dismukes WE, Dromer F, Goldman DL, Graybill JR, Hamill RJ, et al. Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the Infectious Diseases Society of America. Clinical infectious diseases. 2010 Feb 1;50(3):291-322.

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Published

2018-06-25

How to Cite

Kumar, R., & ., P. (2018). A rare case of fungal meningitis with atypical presentation in immunocompetent patient. International Journal of Research in Medical Sciences, 6(7), 2544–2546. https://doi.org/10.18203/2320-6012.ijrms20182854

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Section

Case Reports