Cervical aspergillosis in a post-menopausal female: a case report

Ashwini Natekar, Shubasis Basu, Gautam Mondal, Maruti Pujari


Fungal infections are commonly encountered in the female genital tract on routine cervical smear examination, the most common being candida. Cervico-vaginal aspergillosis infection is rarely reported. We report a case of aspergillus infection in an immunocompetent 55-year-old post-menopausal female who presented with white discharge per vaginum. Initially the cervical pap smears showed only inflammatory changes. On per speculum examination the cervix appeared congested and ulcerated. Cervical biopsy was performed which showed sheets and balls of aspergillus fungus with areas of necrosis. PAS staining further confirmed the diagnosis.  Serological tests performed were negative. Patient was started on antifungal and repeat biopsy from cervix did not show any fungal hyphae.


Aspergillus, Cervix, Immunocompetent

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Denning DW. Invasive aspergillosis. Clin Infect Dis. 1998;26:781-805.

Young RC, Bennett JE, Vogel CL, Carbone PP, DeVita VT. Aspergillosis: The spectrum of disease in 98 patients. Medicine (Baltimore). 1970;49:147-73.

Meyer RD, Young LS, Armstrong D, Yu B. Aspergillosis complicating neoplastic disease. Am J Med. 1973;54:6-15.

Sullam SA, Mahfouz AA, Dabbous NI, el-Barrawy M, el-Said M. Reproductive tract infections among married women in upper Egypt. East Mediterr Health J. 2001;7:139-46.

Sheyn I, Mira JL, Thompson MB. Paracoccidioides brasiliensis in a postpartum Pap smear. Acta Cytol. 2001;45:79-81.

Micheli PA. Nova plantarum genera. Firenze. 1729;Plate 91.

Latgé JP. Aspergillus fumigates and aspergillosis. Clin Microbiol Rev. 1999;12:310-50.