A study to assess prevalence of treatment default among lung cancer patients registered at a tertiary care hospital

Lokendra Dave, Vikas Mishra, Rakesh C. Gupta, Neeraj Gour, Nishant Shrivastava, Rajveer S. Kuldeep, Meenakshi Chaudhary


Background: Lung cancer is among the five main types of cancer leading to overall cancer mortality contributing about 1.3 million deaths/year globally. Completion of treatment among lung cancer patients is one of key factor for the survival and longevity of patients. So, we have tried to find out prevalence of treatment default through this study.

Methods: This is a cross-sectional descriptive study (including retrospective secondary and prospective primary data) using data base of patients of primary lung cancer diagnosed between 1st January 2006 to 31st December 2012 in indoor and outdoor of department of Respiratory Medicine, J.L.N. Medical College, Ajmer, a tertiary level hospital and teaching center.

Results: Incidence of lung cancer is significantly higher among young female (10.23%) as compared to young male (8.74 %). Whereas in older group number of male suffering from lung cancer than female. Total 269 (20.7%) patients defaulted from planned treatment and most of them ultimately drop-out from chemotherapy cycles. Intercycle delay of 2 weeks-1m commonly seen.

Conclusions: It provides future implication to researchers to explore reasons of these defaults and drop outs so that more evidences can be generated in this direction for the ultimate betterment of lung cancer patients.


Lung cancer, Treatment default

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World health organization. Cancer key facts. 2018. Available from: factsheets/fs297/en/index.html. Last accessed on January 2012.

World Health Organization. Global status report on noncommunicable diseases 2014. Available from: Accessed on January 2012.

McDuffie HH, Klaassen DJ, Dosman JA. Characteristics of patients with primary lung cancer diagnosed at age of 50 years or younger. Chest. 1986;96:1298-1301.

Jubelirer SJ, Wilson RA. Lung cancer in patients younger than 40 years of age. Cancer. 1991;67:1436-8.

Kosmider S, Sheddha S, Jones IT McLaughlin S, Gibbs P. Predictors of clinic non-attendance-opportunities to improve patient outcome in colorectal cancer. Intern Med J. 2010;40:757-63.

Klosky JL, Cash DK, Buscemi J, Lensing S, Garces-Webb DM, Zhao W, et al. Factors influencing long-term follow up clinic attendance among survival of childhood cancer. J Cancer Sur. 2008;2:225-32.

Johnson R, Horne B, Feltbower RG, Butler GE, Glaser AW. Hospital attendance patterns in long term survivors of cancer. Arch Dis Child. 2004;89:374-7.

Jeyalakshmi S, Chakrabarti S, Gupta N. Situation analysis of the elderly in India. Central Statistics Office, Ministry of Statistics and Programme Implementation, Government of India document. 2011 Jul 4.

Jindal SK, Behera D. Clinical spectrum of primary lung cancer: Review of Chandigarh experience of 10 years. Lung India. 1990;8:94-9.

Gupta RC, Purohit SD, Sharma MP, Bhardwaj S. Primary bronchogenic carcinoma: Clinical profile of 279 cases from mid-west Rajasthan. Indian J Chest Dis Allied Sci. 1998;40:109-16.

Prasad R, James P, Kesarwani V, Gupta R, Pant MC, Chaturvedi A, et al. Clinicopathological study of bronchogenic carcinoma. Respirology. 2004;9:557-60.

Rao S, Rau PV, Sahoo RC. Bronchogenic carcinoma in the young. Lung India. 1992;10:101-2.

Sirsat MV. Some aspects of the pathology of primary carcinoma of the lung. J Post Grad Med. 1958;4:6-14.

Ng TH, How SH, Kuan YC, Fauzi AR. Defaulters among lung cancer patients in a suburban district in a developing country. Ann Thorac Med. 2012;7:12-5.

Lee VJ, Earnest A, Chen MI, Krishnan B. Predictors of failed attendances in a multi-specialty outpatient centre using electronic databases. BMC Health Serv Res. 2005;6;50-1.

Hutchins LF, Unger JM, Crowley JJ, Coltman Jr CA, Albain KS. Underrepresentation of patients 65 years of age or older in cancer-treatment trials. New Eng J Med. 1999 Dec 30;341(27):2061-7.

Davidoff AJ, Tang M, Seal B, Edelman MJ. Chemotherapy and survival benefit in elderly patients with advanced non-small-cell lung cancer. J Clin Oncol. 2010 Mar 29;28(13):2191-7.

Chung JW, Wong TK, Teung AC. Non-attendance at an orthopaedic and trauma specialist outpatient department of a regional hospital. J Nurs Manag. 2004;12:362-7.

Wong TY, Pang AL, Chu WC, Choi M, Lam WW. Audit of attendance for scheduled breast imaging examinations. J HK Coll Radiol. 2003;6:78-80.

Akhtar PS, Masud ZM, Alam MT, Begum M. Profile of lung cancer: a one-year report. J Med. 2011;12(2):115-9.