Management and outcome of community acquired pneumonia: hospital based study

Avinash Lamb, Amol Harinathrao Patil


Background: Lower Respiratory Tract infections are responsible for one-fifth of the deaths caused due to infectious diseases in India and Pneumonia is a major culprit. Timely and appropriate empirical treatment based on knowledge of local etiological factors is important in the management of the disease. Data related to investigation profile and therapy as well as morbidity and mortality is available from different geographic regions. Present study describes the management and outcome of disease data from a tertiary hospital at Rajkot in Gujarat state during the study period.

Methods: The present prospective observational study was completed in the study duration (November 2014 to April 2016) at tuberculosis and chest diseases Department of PDU Hospital at Rajkot, Gujarat. 50 patients above 12 years of age with CAP on clinical diagnosis assisted by radiology were included in the study. The haematology profile, therapy, complications and mortality were described.

Results: Haemoglobin was below 10gm percent in 22% cases. Leucocytosis was observed in 72% cases. Ten percent patients were seropositive for HIV. There was a moderate response to treatment with penicillin group of drugs (approximately 22%). Many patients had to be offered other group of drugs like Cephalosporins, macrolides and quinolones for clinical response. Most common complications observed were: Delayed resolution in 12 (24%) patients, synpneumonic effusion in 6 (12%) and septicaemia in 3 (6%) patients. Mortality rate was 6% during the study period.

Conclusions: The results indicate a low response to treatment by penicillin group antibiotics and a high rate of complications. Mortality is similar to reports from India.


Cephalosporins, Mortality, Penicillin

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Lozano R, Naghavi M, Foreman K, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2013;380:2095-128.

World Health Organization. Global burden of disease (GBD). Geneva: World Health Organization; 2008. Available at:

Gupta D, Agarwal R, Aggarwal AN, Singh N, Mishra N, Khilnani GC, et al. Guidelines for diagnosis and management of community-and hospital-acquired pneumonia in adults: Joint ICS/NCCP(I) recommendations. Lung India. 2012;29,Suppl S2:27-62.

Jain SK, Jain S, Trikha S. Study of clinical, radiological, and bacteriological profile of community-acquired pneumonia in hospitalized patients of Gajra raja medical college, Gwalior, Central India. Int J Sci Stud. 2014;2(6):96-100.

Khadanga S, Karuna T, Thatoi PK, Behera SK. Changing bacteriological profile and mortality trends in community acquired pneumonia. J Global Infect Dis. 2014;6:186-8.

Para RA, Fomda BA, Jan RA, Shah S, Koul PA. Microbial etiology in hospitalized North Indian adults with community-acquired pneumonia. Lung India. 2018;35:108-15.

Mandell LA, Wunderink RG, Anzueto A, Bartlett GJ, Campbell GD, Dean NC, et al. Infectious Disease Society of American/American Thoracic Society consensus guidelines for the management of community acquired pneumonia in adults. Clin Infect Dis. 2007;44:S27-72.

Feikin DR, Feldman C, Schuchat A, Janoff EN. Global strategies to prevent bacterial pneumonia in adults with HIV disease. Lancet Infectious Diseases. 2004;4(7):445-55.

Oberoi A, Aggarwal A. Bacteriological profile, serology and antibiotic sensitivity pattern of micro-organisms from community acquired pneumonia. JK Science. 2006;8(2):79-82.

Prasad P, Bhat S. Clinicomicrobiological study of community-acquired pneumonia. Lung India. 2017;34:491-2.

Capoor MR, Nair D, Aggarwal P, Gupta B. Rapid diagnosis of community-acquired pneumonia using the BacT/Alert 3D system. Braz J Infect Dis. 2006;10:352-6.

Shah BA, Singh G, Naik MA, Dhobi GN. Bacteriological and clinical profile of Community acquired pneumonia in hospitalized patients. Lung India: Official Organ of Indian Chest Society. 2010;27(2):54-7.