Screening of gestational diabetes mellitus in antenatal women using DIPSI guidelines
DOI:
https://doi.org/10.18203/2320-6012.ijrms20160293Keywords:
Gestational diabetes mellitus, DIPSIAbstract
Background: GDM is associated with serious maternal as well as fetal complications, which can be prevented by early detection & prompt treatment. There is need of universal screening of all Indian pregnant women for GDM using simple & economical screening criteria. This study uses single step OGTT as per DIPSI guidelines to find out prevalence of GDM in pregnant women attending antenatal OPD.
Methods: All the antenatal patients at 24-28 weeks of gestation (n = 352), attending Antenatal OPD, irrespective of their prandial state were given 75 gm glucose and venous blood samples were collected after 2 hours of oral glucose. A report of ≥140 mg% were labeled as GDM as per DIPSI guidelines.
Results: Out of 506 subjects screened, 33 (6.52 %) were positive for GDM.
Conclusions: Low prevalence of GDM may be because of less sensitivity of DIPSI criteria.
References
Metzger BE, Coustan DR. Summary and recommendations of the Fourth International Workshop-Conference on Gestational Diabetes Mellitus: the Organizing Committee. Diabetes Care. 1998;21:B161-7.
Landon MB, Mele L, Spongy CY. Relationships between maternal glycemia and perinatal outcome. Obstet Gynecol. 2011;117:218-24.
Landon MB, Spong CY, Thom E, Carpenter MW. A multicenter randomized trial of treatment for mild gestational diabetes. N Engl J Med. 2009;361:1339-48.
Yogev Y, Chen R, Langer O, Hod M. Diurnal Glycemic profile characterization in non diabetic non obese subjects during the first trimester. The 37th Annual Meeting Of The Diabetes And Pregnancy Study Group, Myconos-Hellas. 2005.
Dabelea D, Hanson RL, Bennett PH, Roumain J, Knowler WC, Pettitt DJ. Increasing prevalence of type II diabetes in American Indian children. Diabetologia. 1998;41:904-10.
Seshiah V, Balaji V, Madhuri S Balaji, Sanjeevi CB, Green A. Gestational Diabetes Mellitus in India. J Assoc Physic of India. 2004;52:707-11.
Chen Y, Quick WW, Yang W, Zhang Y, Baldwin A. Cost of gestational diabetes in the United States in 2007. Population Health Management. 2009;12:165-74.
Dornhost A, Paterson CM, Nicholls JS, Wadsworth J, Chiu DC, Elkeles RS, et al. High prevalence of GDM in women from ethnic minority groups. Diabetic Med. 1992;9:820-2.
Seshiah V, Das AK, Balaji V, Joshi SR, Parikh MN, Gupta S. Gestational Diabetes Mellitus- Guidelines. JAPI. 2006;54:622-2.
Seshiah V. One Step procedure for screening and diagnosis of gestational diabetes mellitus. J Obstet Gynecol India. 2005;55:525-2.
Trinder P, Ann. Clin. Biochem. 1969;6:24-7.
Anjana RM, Pradeepa R, Deepa M, Datta M, Sudha V, Unnikrishnan R. ICMR-INDIAB Collaborative Study Group. Prevalence of diabetes and prediabetes (impaired fasting glucose and/or impaired glucose tolerance) in urban and rural India: Phase I results of the Indian Council of Medical Research-India Diabetes (ICMR-INDIAB) study. Diabetologia. 2011;54:3022-7.
Mohan V, Sandeep S, Deepa R, Shah B, Varghese C. Epidemiology of type 2 diabetes: Indian scenario. Indian J Med Res. 2007;125:217-30.
Seshiah V, Balaji V, Balaji MS, Paneerselvam A, Arthi T, Thamizharasi M, et al. Prevalence of gestational diabetes mellitus in South India (Tamil Nadu)- a community based study. J Assoc Physicians India. 2008;56:329-33.
Parikh P, Shah A, Joshi D, Shah R. Prevalence of gestational diabetes mellitus at tertiary care center. IJSRP. 2014;4:9.
Gopalakrishnan V, Singh R, Pradeep Y, Kapoor D, Rani AK, Pradhan S. Evaluation of the prevalence of gestational diabetes mellitus in North Indians using the International Association of Diabetes and Pregnancy Study groups (IADPSG) criteria. J Postgrad Med. 2015;61:155-8.
Mohan V, Mahalakshmi MM, Bhavadharini B, Maheswari K, Kalaiyarasi G, Anjana RM. Comparison of screening for gestational diabetes mellitus by oral glucose tolerance tests done in the non-fasting (random) and fasting states. Acta Diabetol. 2014;51:1007-13.
Vij P, Jha S, Gupta SK, Aneja A, Mathur R, Waghdhare S. Comparison of DIPSI and IADPSG criteria for diagnosis of GDM. A study in a north Indian tertiary care center. Int J Diabetes Dev Ctries. 2015.
Seshiah V, Sahay BK, Das AK, Balaji V, Shah S, Banerjee S. Diagnosis and management of gestational diabetes mellitus: Indian guidelines. In: Muruganathan A, editor. Medicine Update 2013. Jaybee Brothers Publishers, New Delhi: The Association of Physicians of India. 2013:201-204.