Forced vital capacity, forced expiratory volume in 1st second and forced expiratory ratio in automobile spray paint workers

Geetika Gupta; Sabita Yograj; Anil K. Gupta; Bhavna Langer; Mumtaz Goni

doi:10.18203/2320-6012.ijrms20162602

Authors

Geetika Gupta Department of Physiology, ASCOMS, Jammu, Jammu and Kashmir
Sabita Yograj Department of Physiology, ASCOMS, Jammu, Jammu and Kashmir
Anil K. Gupta Department of Medicine, ASCOMS, Jammu, Jammu and Kashmir
Bhavna Langer Department of Community Medicine, GMC, Jammu, Jammu and Kashmir
Mumtaz Goni Department of Physiology, ASCOMS, Jammu, Jammu and Kashmir

DOI:

https://doi.org/10.18203/2320-6012.ijrms20162602

Keywords:

Forced vital capacity, Forced expiratory volume in 1st second, Forced expiratory ratio

Abstract

Background: Automobile industry is a place where workers are exposed to harmful chemicals and toxic substances. Workers engaged in automobile spray painting are at a risk of developing respiratory problems. This is due to exposure to low molecular weight compounds (isocyanates) in spray paints.

Methods: The present study was conducted on 100 male subjects comprising of the study group (n=50) and the control group (n=50), 18-35 years of age, non-smoker and with no pre occupational respiratory illness. The study group included workers working for 6-8 hours a day and exposed to spray paints for ≤5 years and the controls were age and BSA matched healthy office workers of the same locality. A preformed questionnaire was given to subjects and pulmonary functions parameters (forced vital capacity (FVC), forced expiratory volume in 1st second (FEV1), forced expiratory ratio (FEV1/FVC)) were recorded by computerised spirometer (Medspiror).

Results: The two groups did not differ significantly on physical parameters. The pulmonary function parameters of the study group (FVC p=0.036, FEV1/FVC p=0.000) were found to be significantly different when compared to that of controls. As the age, weight, height and BSA increases there was a significant decrease in FEV1 in study group. Duration of exposure (<3 and more than equal to 3) had no statistically significant impact on pulmonary function tests (FVC p=0.139, FEV1 p=0.339, FEV1/FVC p=0.158) in the study group.

Conclusions: Exposure to automobile spray paint impairs lung functions.

Metrics

Metrics Loading ...

References

Ayers LN. Carbon mono-oxide diffusing capacity. In: Wilson AF. Pulmonary Function Testing Indications and Interpretation. Grune and Stratton, New York;1985:1-8.

Bouhuys A: Breathing-Physiology, Environment and Lung Disease. Newyork: Grunne and Statton; 1974:261,342-344.

National Institute of occupational safety and health in automobile repair shops. Cincinnati: US Department of health and human services; 1977.

Banks DE, Butcher BT, Salvaggio JE. Isocyanate induced respiratory disease. Ann Allergy. 1986;57:389-97.

Occupational health clinics for ontario workers inc.org isocyanates in autobody repair. Available at: http://www.ohcow.on.ca. Accessed on 04 September 2010.

Lesage J, Goyer N, Desjardins F, Vincent JY, Perrault G. Workers-exposure to isocyanates. Am Ind Hyg Assoc J. 1992;53:146-53.

Wisnewski AV, Redlich C, Mapp C, Bernstein IL, ChanYM, Malo JL. Asthma in the workplace. New York: Taylor and Francis Group;2006:481-504.

Sparer J, Stowe MH, Bello D. Isocyanate exposure in autobody ship workers the spray study. J Occup Environ Hyg. 2004;1(9);570-81

Ott MG. Occupational asthma, lung function decrement and toluene diisocyanate (TDI) exposure: a critical review of exposure response relationships. Appl Occup Environ Hyg. 2002;17;891-901.

Chattopadhyay O. Pulmonary function in automobile repair workers. Indian J Community. 2007;32(1):1-3.

Hankinson JL, Reger RB, Fairman RP, Lapp NL, Morgan WK. Factors influencing expiratory flow rates in coal miners. In: Walton WH. Inhaled Particles IV, Pergamon Press, Oxford;1975:737-755.

American Thoracic Society. Lung function testing: selection of reference values and interpretative strategies. Am Rev Respir Dis. 1991;144:1202-18.

Cotes JE. Lung functions assessment and application in medicine. 4th ed.; Blackwell Scientific Publication;London;1979:314,315,329,330.

Dahlqvist M, Tornling G, Plato N, Ulfvasa U. Effects within the week on forced vital capacity are correlated with long term changes in pulmonary function: reanalysis of studies on car painters exposed to isocyanate. Occupational Environ Med. 1995;52:192-5.

Baur X. Hypersensitivity pneumonitis (extrinsic allergic alveolitis) induced by isocyanates. J Allergy Clin Immunol. 1995;95:1004-10.

Aggarwal AN, Gupta D, Behera D, Jindal SK. Applicability of commonly used caucasian prediction equation for spirometry interpretation in India. Indian J Med Res. 2005;122(2):93-186.

Mapp CE, Boschetto P, Dal VL, Fabri LM. Occuopational asthma due to isocyanate. Eur Respir J. 1988;1:273-9.

Bascom R. Isocyanates asthma: the proceedings. Am Thoracic Soc. 2008;5:751-4.

Jonson B, Bitzen U. Clinical utility of lung mechanics measurements. J Organ Dysfunction. 2008;41:38-42.

Chattopadhyay O. Pulmonary function in automobile repair workers. Indian J Community Med. 2007;32(1):40-2.

Revathi M, Chandrasekhar M. Pulmonary functions in short duration exposed automobile spray painters. IOSR J Dental Med Sci. 2012;2(2):48-51.

Siddanagoudra SP, Kanyakumari DH, Nataraj SM. Respiratory morbidity in spray paint workers in an automobile sector. Int J Health Allied Sci. 2012;1(4):268-73.