DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20160305

Seroprevalence of hepatitis b in healthy blood donors at a teaching hospital of Kashmir (skims medical college and hospital Bemina, Srinagar): a restrospective study of five years

Mohd Younus Shah, Mohd Mubarik Naqash, Faizan Younus Shah

Abstract


Background: The study was conducted at the blood bank of the hospital. It was a retrospective analysis of blood donors over a period of five years from April 2008 to March 2013.

Methods: 5ml blood sample was collected from the blood bag of each donor. 2ml blood was kept for testing hepatitis B. Bioelisa HBsAg color (a 3rd generation ELISA kit) was used for the screening of donor blood for Hepatitis B. All reactive samples were tested again using the same ELISA kit. Samples showing repeat test reactivity on both methods were considered positive and were included for calculation of seroprevalence. Chi-square test was used to calculate the significance of difference between the groups.

Results: Total numbers of donors were 4880. Out of them, only 17 were Seropositive (Prevalence of 0.35% i.e. Low prevalence).

Conclusions: Kashmir region is one of the few regions from India where seroprevalence of HBsAg is low.


Keywords


Hepatitis B, Seroprevalence, SKIMS, Kashmir, Blood Donors, Five year study

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References


Prevention of hepatitis B in India. An overview World Health Organization. New Delhi. 2002.

Purow DB, Jacobson IM. Slowing the progression of chronic hepatitis B: early antiviral therapy can help minimize complications. Postgrad Med. 2003;114;65-76.

Gupta N, Vijay K, Jaur A. Seroprevalence of HIVk, HBV and symphilis in voluntary blood donors. India Journal of Medical Sciences. 2004;54:255-7.

Zacharias P. Prevalence of HBV and HIV in voluntary blood donors in North Kerala. Indian J Gastroenterology. 2005;24:A-107.

Bhattacharya P, Chandra PK, Datta S. Significant increase in HBV, HCV, HIV and syphilis infections among blood donors in West Bengal, Eastern India 2004-2005: exploratory screening reveals high frequency of occult HBV infection. World J Gastroenterol. 2007;21;3730-3.

Nandi J, Bhawalkar V, Mody H. Detection of HIV-1, HBV and HCV antibodies in blood donors from Surat, Western India Vox Sang. 1994;67(4):406-7.

Kayani N, Asim M, Ali R, Kar P. Significance of anti-HBc screening of blood donors for the prevalence of HBV infection. Indian Journal of Gastroenterology. 2004;23:A53.

Chandrasekaran S, Palaniappan N, Krishnan V, Mohan G, Chandrasekaran N. Relative prevalence of hepatitis B viral markers and hepatitis C virus antibodies (anti HCV) in Madurai, South India. Indian J Med Sci. 2000;54;270-3.

Rodenas JG, Bacasent LC, Que ER. The prevalence of HBsAg(+) and anti HCV(+) and anti HCV(+) among healthy blood donors at East Avenue Medical Center, Quezon City. Phil J of Gastroenterology. 2006;2;64-70.

Patil AV, Pawar SD, Pratinidhi AK. Study of prevalence, trend and correlation between infections disease markers of blood donors. Indian Journal of Hematology and Blood Transfusion.1996;14:95-102.