Clinicopathological study of breast lesions over a period of one year in a tertiary care center

Divyasree Neeli; Bhagyalakshmi Atla; Satish Kumar Seeram; Lavanya Latchupatula; Srikanth Reddy Kamireddy

doi:10.18203/2320-6012.ijrms20184053

Authors

Divyasree Neeli Department of Pathology, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India
Bhagyalakshmi Atla Department of Pathology, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India
Satish Kumar Seeram Department of Pathology, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India
Lavanya Latchupatula Department of Pathology, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India
Srikanth Reddy Kamireddy Department of Pathology, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20184053

Keywords:

Breast carcinoma, Fibroadenoma, Infiltrating ductal carcinoma

Abstract

Background: Breast carcinoma is no longer seen as a single disease but rather a multifaceted disease comprised of distinct biological subtypes with varied natural history, presenting a diverse spectrum of clinico-pathological and molecular features with different therapeutic and prognostic implications. The present study was designed to evaluate the frequency, age, gender and histopathological features of breast carcinoma in a tertiary care hospital.

Methods: The present study is a hospital based retrospective study for a period of one year from January 2015 to December 2015, conducted in the Department of Pathology, Andhra Medical College, Visakhapatnam.The clinical details were recorded as per the proforma. Tissue for H&E sections were fixed in 10% formalin and subjected to routine paraffin embedded processing and stained with Hematoxylin and Eosin.

Results: Out of the total 185 cases of breast lesions, 151 cases (81.62%) were diagnosed as non-malignant and 34 cases were malignant (18.37%). Maximum number of patients, 106 cases (57.2%), were between 21 - 40 years. Out of 34 malignant breast lesions, 27 were diagnosed as Infiltrative duct cell carcinoma (79.41%), followed by medullary carcinoma 4 cases (11.76%).

Conclusions: The pattern of breast lesions provides valuable information concerning clinicopathological profile of breast lesions. The clinical diagnosis of a breast lump must be correlated with histopathological diagnosis for correct and adequate treatment of patient.

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