Effect of severity of hypertension on brain stem auditory evoked potentials

Authors

  • Roseline Jesintha V. Department of Physiology, Govt. Sivagangai Medical College, Sivagangai, Tamil Nadu, India
  • Vinupradha P. P. Department of Physiology, Govt. Medical & ESI Hospital, Coimbatore, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20184054

Keywords:

Brain stem auditory pathway, Brainstem auditory evoked response, Hypertension, Inter peak latency

Abstract

Background: Hypertension is one of the most important public health problems among worldwide. Central nervous system dysfunctions are common in these patients due to micro-infarctions caused by arteriolar spasm of cerebral blood vessels. This will lead to hypoperfusion, subcortical white matter demyelination, and cognitive decline. The Brainstem auditory evoked potentials (BAEP) are far field subcortical electrical potentials which provide an objective electrophysiological method for assessing the auditory pathway from auditory nerve to the brainstem. Aim and objective of the study was to assess the effect of increasing severity of hypertension on the brainstem auditory pathway, among the patients of essential hypertension.

Methods: A total of 75 subjects of age group 30 to 60 years were included in the study. Among them 25 were healthy age and sex matched controls (Group I), 25 were stage 1 hypertensives (Group IIa) and 25 were stage 2 hypertensives (Group IIb) as per JNC 7 criteria. The absolute latencies I, III, V and interpeak latencies (IPL) I-III, III-V, I-V were recorded by using Neuroperfect EMG 2000 system with installed BAER and data were statistically analyzed using Student unpaired t test.

Results: All the hypertensive (Group IIa and IIb) patients were found to have significantly prolonged absolute latency of wave III, V and IPL III-V, I-V as compared to that of normal healthy controls. The wave V latency was prolonged as the severity of hypertension increased. Intergroup comparison among hypertensive patients (Group IIa and IIb) revealed a significant prolongation of absolute latency of Wave III, V and IPL III-V, I-V.

Conclusions: The results show that there exists a sensory deficit along with synaptic delay across the auditory pathway in the hypertensive patients and the sensory deficit progresses with the severity of the disease.

Author Biography

Vinupradha P. P., Department of Physiology, Govt. Medical & ESI Hospital, Coimbatore, Tamil Nadu, India

 

 

References

Williams GH. In: Isselbacher KJ, Braunwald E, Wilson JD, Martin, JB, Fauci AS, Kasper DL Eds, Harrisons principles of Internal medicine 13th Edition. New York, McGraw-Hill Inc; 1994:1116-1131.

Fredric MW. Cerebrovascular disease. In: Conn HL, Horwitz O, editors. Cardiac and vascular diseases. Philadelphia: Lea and Febiger; 1971:1473-1499.

Scheinberg P. Dementia due to vascular disease: a multifactorial disorder. Stroke. 1988;19:1291-99.

Brainstem Auditory Evoked Potentials. Mishra UK, Kalitha J. Clinical Neurophysiology, 2nd Edition. New Delhi: Elsevier publisher; 2008:274-275, 280-285.

Stockard JE, Stockard JJ. Brainstem Evoked Response Audiometry. Arch neurol. 1979;36:823-31.

Tandon OP, Ram D, Awasthi R. Brainstem auditory evoked responses in primary hypertension. Indian J Med Res. 1996;104:311-5.

Khullar S, Gupta N, Babbar R. Auditory Brainstem Responses and Nerve Conduction Velocity in Essential Hypertension. Vascular Disease Prevention. 2009 Apr 2;6(1):51-5.

Goyal G, Mittal A, Chaudhary C, Bachhel R, Grewal S, Rai M. The impact of severity of hypertension on auditory brainstem responses. Int J Med Public Health. 2014;4(3):218.

The seventh report of the Joint National Committee on detection, evaluation and treatment of high blood pressure (JNC-VII). Hypertension. 2003;42:1206.

Stockard JJ. Brainstem and auditory evoked potentials in neurology: methodology, interpretation, clinical evaluation. Electrodiagnosis in clinical neurology; 1980:370-413.

Burkard R, Mcnerney K. Introduction to Auditory Evoked Potentials. Katz J, Wetsky LM, Burkard R, Hood L, editors. Handbook of Clinical Audiology, 6th Edition, Philadelphia: Lippincott Williams and Wilkins; 2009:222-241.

Nigam J, Jain L, Shrivastava A. Brainstem Auditory Evoked Potential in Primary Hypertension. Sch J App Med Sci. 2016;4(7E):2593.

Haldwani DR, Yadav A, Rathore PK, Tandon OP. Brainstem auditory evoked potential responses in primary hypersensitive patients and its correlation with mean arterial blood pressure. Int J Thera Applicati. 2016;32:28-34.

Chen YL, Ding YP. Relationship between hypertension and hearing disorders in the elderly. East Afr Med J. 1999;76:344-7.

Karamitsos DG, Kounis NG, Zavras GM, Kitrou MP, Goudevenos JA, Papadaki PJ, et al. Brainstem auditory evoked potentials in patients with ischemic heart disease. Laryngoscope. 1996;106:54-7.

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Published

2018-09-25

How to Cite

V., R. J., & P., V. P. (2018). Effect of severity of hypertension on brain stem auditory evoked potentials. International Journal of Research in Medical Sciences, 6(10), 3403–3407. https://doi.org/10.18203/2320-6012.ijrms20184054

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Original Research Articles