Antimicrobial susceptibility pattern of bacterial isolates in patients of chronic suppurative otitis media in a tertiary care hospital in India
DOI:
https://doi.org/10.18203/2320-6012.ijrms20184434Keywords:
CSOM, Ear discharge, Pseudomonas, StaphyloccusAbstract
Background: Chronic suppurative otitis media (CSOM) is a massive public health problem in developing countries like India, especially among low socio-economic class because of malnutrition, overcrowding, poor hygiene, inadequate health care and recurrent upper respiratory tract infections. CSOM cases unless managed effectively may land into various complications such as persistent otorrhoea, hearing impairment, mastoiditis, labyrinthitis, facial nerve paralysis to more serious intracranial abscesses.
Methods: The study was carried out in a tertiary care hospital from January 2017 to December 2017 with an aim to determine the microbiological profile of ear discharge in patients suffering from CSOM and their antimicrobial susceptibility pattern using Kirby Bauer disc diffusion method.
Results: Out of 630 samples processed, 407 (64.6%) samples were culture positive. Most common organism isolated was Pseudomonas spp. (43.2%) followed by S. aureus (39.1%). Most of isolates recovered were multidrug resistant.
Conclusions: Management of CSOM consists mainly of eradicating infection and closure of tympanic membrane. Periodic monitoring of bacterial isolates and their antibiotic susceptibility pattern is necessary for administering appropriate antibiotics as empirical treatment and also helps in reducing the potentially disabling and fatal complications of CSOM.
References
Iseh KR, Adegbite T. Pattern and bacteriology of acute supportive otitis media in Sokoto, Nigeria. Annals African Med. 2004;3(4):164-66.
Krišto B, Buljan M. Microbiology of the chronic suppurative otitis media. Medicinski Glasnik. 2011;8(2):284-6.
Srivastava A, Singh R, Varshney S, Gupta P, Bist S, Bhagat S, et al. Microbiological evaluation of an active tubotympanic type of chronic suppurative otitis media. Nepalese Nepalese J ENT Head Neck Surg. 2010;1(2):14-6.
Samanth TU, Jha SG, Sinha V, Dadhich S. Bacteriology and drug susceptibility in chronic suppurative otitis media in ear, nose, and throat outpatient and inpatient department of tertiary care Hospital, Bhavnagar. Indian J Otol. 2017;23(4):252-5.
Kumar S, Sharma R, Saxena A, Pandey A, Gautam P, Taneja V. Bacterial flora of infected unsafe CSOM. Indian J Otology. 2012;18(4):208-11.
Malkappa KS, Kondapaneni S, Supam BR, Chakraverti KT. Study of bacterial isolates and their antibiotic susceptibility pattern in Chronic Supperative Otitis Media. Indian J Otol. 2012;18(3):136-9.
Loy AHC, Tan AL, Lu PKS. Microbiology of chronic supurative otitis media in Singapore. Singapore Med J. 2002;43(6):296-9.
Sweeney G, Piccozi GL, Browning GG. A quantitative study of aerobic and anaerobic bacteria in chronic suppurative otitis media. J Infection. 1982;5:47-55.
Clinical and Laboratory Standard Institute. Performance standards for antimicrobial susceptibility testing Wayne, PA. 26th ed. CLSI supplement M100-S25. 2016;36(1).
Prakash R, Juyal D, Negi V, Pal S, Adekhandi S, Sharma M, et al. Microbiology of chronic suppurative otitis media in a tertiary care setup of Uttarakhand state, India. North Am J Med Sci. 2013 Apr;5(4):282.
Berman S. Otitis media in children. N Eng J Med. 1995;332(9230):1560-5.
Raakhee T, Unguturu SR. Bacteriological study of discharging ear in patients attending a tertiary care hospital. Int J Res Med Sci. 2014 May;2(2):602-6.
Panchal PD, Patel BV. Evaluation of bacteriological profile and antibiotic susceptibility pattern of patients with otorrhea in a tertiary care teaching hospital. Inter J Res Med Sci. 2017 Jan 16;3(11):3167-70.
Kumar R, Srivastava P, Sharma M, Rishi S, Nirwan PS, Hemwani K, et al. Isolation and antimicrobial sensitivity profile of bacterial agents in chronic suppurative otitis media patients at Nims Hospital, Jaipur. Inter J Pharm Biol Sci. 2013;3(4):265-9.
Malkappa KS, Kondapaneni S, Supam BR, Chakraverti KT. Study of bacterial isolates and their antibiotic susceptibility pattern in chronic suppurative otitis media. Indian J Otol. 2012;18(3):136-9.
Parveen SS, Rao JR. Aerobic bacteriology of Chronic Suppurative Otitis Media (CSOM) in a teaching hospital. J Microbiol Biotechnol Res. 2012;2(4):586-9.
Chavan A, Nagarkar R, Chavan GN, Deshmukh PT. A study of microbiological spectrum with its antibiotic susceptibility in patients of chronic suppurrative otitis media at RIMS, Adilabad. Int J Healthcare Biomed Res. 2014;03(1):152-7.
Arif D, Mukhia RK, Goud SK, Nissar J, Shah RP, Singh S, et al. Bacteriological profile of ear infections and its antibiotic susceptibility pattern in tertiary care hospital Navi Mumbai. IOSR J Dent Med Sci. 2014;13(5):58-62.