Published: 2018-11-26

Prevalence of female reproductive tract cancer in a teaching hospital of Rohtas District, Bihar, India

Rajendra Kumar


Background: The organs of female reproductive tract are involved by various ailments up to malignancy and different types of malignancy involve these organs causing unbearable symptoms to the patient and harassment to the affected family. However, the incidence varies, and cervical carcinoma is more common in Asian countries even after use of screening tests in specialized hospitals. The study was undertaken to assess the prevalence   of malignancy of these organs among females in this location of Rohtas district of Bihar.

Methods: A study of female reproductive system was done retrospectively for a period of 3 years and the suspected 1409 patients underwent operative procedures and tissues were microscopically examined of haematoxylin and eosin stained slides by conventional methods.

Results: Of the 58 malignant cases of female reproductive organs, cervical carcinoma emerged as the commonest with 56.9%, followed by endometrial carcinoma (22.4%), and ovarian cancers (15.5%). The vaginal and vulval cancers were found to be the lowest with 3.4% and 1.7% cases respectively.

Conclusions: The squamous cell carcinoma (67%) was the commonest malignancy of cervical cancers whereas adenocarcinoma (85%) was the most common involvement of endometrial carcinoma histologically diagnosed.


Cervical carcinoma, Endometrial carcinoma, Female reproductive tumors, Ovarian cancers, Vaginal cancers

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Dalsaniya M, Choksi TS, Shrivastava A, Agnihotri AS. Retrospective and prospective histopathological study of tumors and tumor-like lesions of female genital tract. Int J Med Sci Public Health. 2015;4(11):1602-04.

Arya A, Narula R, Singh S, Narula K. Benign and malignant tumors of cervix: 10 years study. Int J Med Health Sci. 2015;4(2):186-89.

Dhakal HP, Pradhan M. Histopathological pattern of gynecological cancers. J Nepal Med Assoc. 2009;48:301-05.

Moore MA, Sobue T. Strategies for cancer control on an organ-site basis. Asian Pac J Cancer Prev. 2010(Suppl);11:149-64.

Vigneri P, Frasca F, Sciacca L, Pandini G, Vigneri R. Diabetes and cancer. Endocr Relat Cancer. 2009;16:1103-23.

Gaur DS, Kishore S, Harsh M, Kusum A, Bansal R. Pattern of cancers amongst patients attending Himalayan Institute of Medical Sciences, Dehradun. Indian J Pathol Microbiol. 2006;49:193-8.

Jeph V, Adreena, Garg PK, Mahabole K. Incidence of different malignancies in female genital tract: study in 504 women in rural population. Int J of Contemporary Med Res. 2017;4(1):284-6.

Binu VS, Chandrashekhar TS, Subba SH, Jacob S, Kakria A, Gangadharan P, Menezes RG. Cancer pattern in Western Nepal: a hospital based retrospective study. Asian Pac J Cancer Prev. 2007;8:183-6.

Pradhan M, Dhakal HP, Pun CB, Pradhan S, Dangal G. Gynecological malignancy in BPKMCH, Bharatpur: a retrospective analysis of 321 cases. J Nepal Med Assoc. 2001;40:108-11.

Anand M, Deshmukh SD, Gulati HK. Anand M, Deshmukh SD, Gulati HK. Papillary squamotransitional cell carcinoma of the uterine cervix: A histomorphological and immunohistochemical study of nine cases. Ind J of Med and Ped Oncol. 2013;34(2):66-71.

Ikechebelu JI, Onyiaorah IV, Ugboaja JO, Anyiam DC, Eleje GU. Clinicopathological analysis of cervical cancer seen in a tertiary health facility in Nnewi, south-east Nigeria. J Obstet Gynaecol. 2010;30:299-301.

Olatunji AO, Sule-Odu AO. Cancer of the cervix. Niger Postgrad Med J. 2005;12:308-11.

D’alo D, Stracci F, Cassetti T, Scheibel M, Pascucci C, La Rosa F. Recent trends in incidence, mortality and survival after cancer of the female breast and reproductive organs. Umbria, Italy: 1978-2005. Eur J Gynaecol Oncol. 2010;31:174-80.

Farrell R, Scurry J, Otton G, Hacker NF. Clinicopathologic review of malignant polyps in stage 1A carcinoma of the endometrium Gynecol Oncol. 2005;98:254-62.

Minar L, Petrovova D, Kummel J. Cancer of endometrium-rare variant of remote metastases. Ceska Gynekol. 2009;74:383-9.

Stanojevic Z, Dordevic B, Zivanovic D. Influence of the primary malignant tumor site on the incidence and features of metastatic ovarian tumors. Vojnosanit Preg. 2007;64:691-6.

Singh N. Synchronous tumours of the female genital tract. Histopathology. 2010;56(3):277-85.

Medard ML, Ostrowska L. Combined oral contraception and the risk of reproductive organs cancer in women. Ginekol Pol. 2007;78:637-41.

Seleye-Fubara D, Uzoigwe SA, Akani CI. Pathology of vaginal cancers in Port Harcourt, Nigeria. A 14-year study. Niger J Clin Pract. 2007;10:330-4.

Zawislak AA, Price JH, Dobbs SP, McClelland HR, McCluggage WG. The management of vulval intraepithelial neoplasia in Northern Ireland. Int J Gynecol Cancer. 2006;16:780-5.

Woolderink JM, de Bock GH, de Hullu JA, Davy MJ, van der Zee AG, Mourits MJ. Patterns and frequency of recurrences of squamous cell carcinoma of the vulva. Gynecol Oncol. 2006;103:293-9.