Transfusion related acute lung injury: a case report

Javier Alcazar Castro; Alejandro Zárate Aspiros; Elias N. Andrade Cuellar; Brenda M. Álvarez Pérez; Alan Isaac Valderrama Treviño; Juan J. Granados Romero; Rodrigo Banegas Ruiz; Baltazar Barrera Mera

doi:10.18203/2320-6012.ijrms20185396

Authors

Javier Alcazar Castro Department of Cardiac Electrophysiology Clinic and Arrhythmias, General Hospital of CDMX, Mexico
Alejandro Zárate Aspiros Anesthesiology Service, General Hospital of CDMX, Mexico
Elias N. Andrade Cuellar Department of Cardiac Electrophysiology Clinic and Arrhythmias, General Hospital of CDMX, Mexico
Brenda M. Álvarez Pérez Department of Cardiac Electrophysiology Clinic and Arrhythmias, General Hospital of CDMX, Mexico
Alan Isaac Valderrama Treviño Laboratory of Experimental Immunotherapy and Tissue Engineering, Faculty of Medicine, UNAM, CDMX, Mexico
Juan J. Granados Romero Department of General Surgery, General Hospital of Mexico, CDMX, Mexico
Rodrigo Banegas Ruiz Service of Hand Surgery and Microsurgery, Rehabilitation Hospital, Luis Guillermo Ibarra Ibarra, CDMX, Mexico
Baltazar Barrera Mera Department of Physiology, Faculty of Medicine, UNAM, CDMX, Mexico

DOI:

https://doi.org/10.18203/2320-6012.ijrms20185396

Keywords:

Acute lung injury, Anaesthesiology, Blood transfusion, Transfusion

Abstract

Transfusion Related Acute Lung Injury (TRALI) is one of the most serious complications of blood transfusion. All blood components have been implicated and most often those that contain plasma. The diagnosis is based fundamentally on the integration of clinical, radiological and gasometry elements, once the rest of the possible causes of acute lung injury have been ruled out. The differential diagnosis of a patient who develops a sudden pattern of respiratory failure after a transfusion of blood products must include hemodynamic overload, anaphylactic reaction, bacterial contamination of transfused blood products, haemolytic transfusion reaction and TRALI. Author presented the clinical case of a 33-year-old female patient with grade III hypovolemic shock due to a ruptured ectopic pregnancy, reanimated with crystalloid solutions, globular packages and fresh frozen plasma. The patient developed TRALI for what was managed with ventilatory and hemodynamic support in ICU.

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