DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20185502

Knowledge, attitude and practices of antibiotic usage among university students from Karachi, Pakistan

Dnyanesh Limaye, Patrick Ziesenis, Vaidehi Limaye, Mansoor Ahmad, Farah Saeed, Ramla Rizvi, Atul Kapadi, Sushama Sathe, Gerhard Fortwengel

Abstract


Background: Antimicrobial resistance has become a serious global problem. A potential post-antibiotic era is threatening present and future medical advances. In Pakistan, the usage of antibiotic is unnecessarily high and due to over exposure to these drugs, bacteria are developing resistance against these drugs. It is necessary to improve public awareness about the rational use of antibiotics in order to bring a change in consumer’s behaviour. Therefore, present study was undertaken to assess the existing knowledge, attitude and practices related to antibiotic usage among university students.

Methods: A cross-sectional study was carried out among university students from Karachi, Pakistan during May-June 2018. 200 students were approached to participate in the study of which 159 agreed to participate (males: 70, females: 89). Pretested questionnaire was distributed to the study subjects and the collected data was analyzed using IBM SPSS version 23.

Results: Substantial number of (33% and 50%) participants were unaware about the differences in antibiotic: anti-inflammatory drugs and antibiotic: antipyretics respectively. 29% of the participants thought it is right to stop antibiotics only based on symptomatic improvement. Thirty nine percent and eighty three percent participants believed that antibiotics should always be prescribed to treat flu like symptoms and pneumonia respectively.

Conclusions: Participants demonstrated average knowledge about antibiotics. Similarly, their attitude and practice toward antibiotic use was associated with misconceptions. An educational intervention is necessary to make them aware about rational use of antibiotics.


Keywords


Antibiotic, Antibiotic resistance, Karachi, Pakistan, University students

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References


Zorzet A. Global Importance of Antibiotics and consequences of antibiotic overuse. AAAS Annual Meeting. 2015:12-6.

Garg R. Tackling antimicrobial resistance: optimizing use of an older antibiotic-amoxicillin. Ind J Clin Pract. 2014;24(9):843-5.

Cars O, Nordberg P. Antibiotic resistance-The faceless threat. Inter J Risk Safety Med. 2005;17:103-10.

Appelbaum PC. 2012 and beyond: potential for the start of a second pre-antibiotic era?. J Antimicrobial Chemotherapy. 2012;67(9):2062-8.

Kaleem F, Usman J, Hassan A, Khan A. Frequency and susceptibility pattern of metallo-beta-lactamase producers in a hospital in Pakistan. J Infection Developing Countries. 2010;4(12):810-3.

Shah SH. Susceptibility patterns of Escherichia coli: Prevalence of multidrug-resistant isolates and extended spectrum beta-Lactamase phenotype. JPMA. 2002;52:407.

Ali I, Kumar N, Ahmed S, Dasti JI. Antibiotic resistance in uropathogenic E. coli strains isolated from non-hospitalized patients in Pakistan. JCDR. 2014;8(9):DC01.

Tanvir R, Hafeez R, Hasnain S. Prevalence of multiple drug resistant Escherichia coli in patients of urinary tract infection registering at a diagnostic laboratory in Lahore Pakistan. Pak J Zool. 2012;44(3):707-12.

Bashir S, Haque A, Sarwar Y, Raza A. Prevalence of integrons and antibiotic resistance amon. Arch Clin Microbiol. 2015;6(4).

Sohail M, Khurshid M, Saleem HG, Javed H, Khan AA. Characteristics and antibiotic resistance of urinary tract pathogens isolated from Punjab, Pakistan. Jundishapur J Microbiol. 2015;8(7).

Kidwai SS, Nageen A, Ghaznavi S, Bashir F, Ara J. Antibiotic susceptibility in commonly isolated pathogens from urinary tract infection in a cohort of subjects from low socioeconomic strata. Pak J Med Sci. 2017;33(2):254.

Dodani S, Nasim A. Changing trends in antimicrobial resistance pattern in klebsiella species bacteremia in an out-patient hemodialysis unit over 6years (2010-2015) in a tertiary care hospital in Pakistan. Open Forum Infec Dis. 2017;4:156.

Ullah F, Malik SA, Ahmed J. Antimicrobial susceptibility pattern and ESBL prevalence in Klebsiella pneumoniae from urinary tract infections in the North-West of Pakistan. African J Microbiol Res. 2009;3(11):676-80.

Lee CR, Cho I, Jeong B, Lee S. Strategies to minimize antibiotic resistance. Inter J Env Res Public Health. 2013;10:4274-305.

Naseem S, Iffat W, Shakeel S, Tariq S. Knowledge about antibiotic use amongst the public: a cross sectional study in karachi. Infectious Dis J Pak. 2016; 25(3): 49-54.

Limaye D, Naware S, Bare P, Dalvi S, Dhurve K, Sydymanov A, et al. Knowledge, attitude and practices of antibiotic usage among students from Mumbai University. Inter J Res Med Sci. 2018;6(6):1908-12.

Igbeneghu OA. Knowledge and practices in the use of antibiotics among a group of Nigerian university students. Inter J Infection Control. 2013;9(1).

Chen C, Chen YM, Hwang KL, Lin SJ, Yang CC, Tsay RWet al. Behavior, attitudes and knowledge about antibiotic usage among residents of Changhua, Taiwan. J Microbiol Immunol Infect. 2005;38(1):53-9.

Buke C, Hosgor-Limoncu M, Ermertcan S, Ciceklioglu M, Tuncel M, Köse T, et al. Irrational use of antibiotics among university students. J Infection. 2005;51(2):135-9.

Carey B, Cryan B. Antibiotic misuse in the community-a contributor to resistance?. Irish Med J. 2003;96(2):43-4.

Liu YC, Huang WK, Huang TS, Kunin CM. Inappropriate use of antibiotics and the risk for delayed admission and masked diagnosis of infectious diseases: a lesson from Taiwan. Arch Internal Med. 2001;161(19):2366-70.

Sarkar P, Gould IM. Antimicrobial agents are societal drugs. Drugs. 2006;66(7):893-901.

Afzal MS. Emergence of antibiotic resistance in pakistan; a clear problem for future. J Vaccines Vaccin. 2017; 8: 375.

Market research and public opinion member of win/gallup international, doctor-patient global communication performance assessment by cat, insights from the worldwide independent network (win™) of market research, Fall, 2011. Available at: http://www.mareco.cz/assets/healthCare_1st.pdf.

Rabbani F, Cheema FH, Talati N, Siddiqui S, Syed S, Bashir S, et al. Behind the counter: pharmacies and dispensing patterns of pharmacy attendants in Karachi. JPMA. 2001;51(4):149.

Qidwai W, Krishanani MK, Hashmi S, Abu Ali R. Private drug sellers education in improving prescribing practices. J Coll Physicians Surg Pak. 2006;16(12):743.

Butt ZA, Gilani AH, Nanan D, Sheikh AL, White F. Quality of pharmacies in Pakistan: a cross-sectional survey. Inter J Quality Health Care. 2005:307-13.

Kuperman AA, Koren O. Antibiotic use during pregnancy: how bad is it?. BMC Med. 2016;14(1):91.

Assari S. Why do women live longer than men? World Economic Forum. 2017. Available at: https://www.weforum.org/agenda/2017/03/why-do-women-live-longer-than-men. Accessed 1 November 2018).