Role of multidetector computed tomography in evaluation of suspected bronchogenic carcinoma

Deepika Yadav, Nikhil Yadav, Rekha Goyal, Manreet Romana


Background: Bronchogenic  carcinoma  is  the  leading cause  of  cancer  deaths  in  developed  countries  and  is  rising  at  alarming  rates  in developing countries. Deaths due to lung cancer are more than those due to colorectal, breast and prostate cancers put together.  CT remains the routine imaging procedure for determining resectability and assessing intra- and extra thoracic spread of lung cancer.

Methods: 30 patients with strong clinical / radiological suspicious of bronchogenic carcinoma were included in this study. MDCT was carried out and its provisional diagnosis of bronchogenic carcinoma was correlated with pathological diagnosis obtained on bronchoscopic biopsy / CT guided FNAC.

Results: Patient’s age ranged between 45 to 80 years with the mean age of 59 years. There was significant male preponderance (26 males) with smoking being the most common risk factor (83.3%). Cough (83.3%) and dyspnea (80%) were the commonest symptoms. The most common radiological manifestation was central hilar mass seen in 20 (66.6%) patients and peripheral mass seen in 10 (33.3%) patients. Provisional CT diagnosis was found in complete correlation with pathological diagnosis made on bronchoscopy biopsy/ CT guided FNAC in 28 (93.3%) patients and others 2 patients diagnosed as pulmonary tuberculosis, non caseating granulomatous inflammation on histopathological diagnosis. Squamous cell carcinoma was the commonest histopathological type seen in 16 (53.3%) patients followed by adenocarcinoma seen in 8 (26.6%) patients.

Conclusions: Multidetector computed tomography plays an important role in evaluating and staging of bronchogenic carcinoma.CT had the high predictive value in evaluating bronchogenic carcinoma and found to be 93.3%.



Multidetector computed tomography, Bronchogenic carcinoma, Bronchoscopic biopsy, CT guided FNAC

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Behera D, Balamugesh T. Lung Cancer in India. Indian J Chest Dis Allied Sci. 2004;46:269-81.

Siegel R, NaishadhamD, Jemal A. Cancer statistics. 2012. CA Cancer J Clin. 2012;62(1):10-29.

Minna JD, Schiller JH, Kasper DL, Fauci AS, Braunwald E. Neoplasms of the Lung.In. Harrisons principles of Internal Medicine. 16 editions. USA: McGraw Hill. 2008:1592-97.

Kitt S. Imaging and Medical Staging Of Lung Cancer, Haematology/Oncology Clinics of North America. 1997;11(2):197-212.

Rivera-Garcia R, White CS, Templeton PA. Lung cancer: value of various imaging modalities. Clinical Lung Cancer. 1999;1(2):130-6.

Verschakelen JA, Bogaert J, Wever WD. Computed tomography in staging for lung cancer EurRespir J. 2002;19(35):40S-48S .

Shetty CM, Lakhkar BN, Gangadhar V, Ramachandran NR. Changing pattern of bronchogenic carcinoma : A statistical variation or a reality?. Indian J Radiol Imaging. 2005;15:233-8.

Henschke CI, Yankelevitz DF, MaCauley DI, Libby DM, Pasmantier MW, Smith JP. Guidelines for use of spiral computed tomography in screening of lung cancer. Eur Respir J. 2003;39:45S-51S.

Arora VK, Seetharaman ML, Ramkumar S. Bronchogenic Carcinoma - Clinico- pathological Pattern In South Indian Population , Lung India. 1990;7(3):133-8.

Krishnamurthy A, Vijayalakshmi R, Gadigi V, Ranganathan R, Sagar TG. The relevance of Nonsmoking-associated lung cancer in India: A single-centre experience. Indian J Cancer 2012;49:82-8 .

Rawat J, Sindhwani G, Gaur D, Dua R, Saini S. Clinico-pathological profile of lung cancer in Uttarakhand. Lung India. 2009;26:74-6.

The American Thoracic Society: Cigratte smoking and health. Am. J. Respir. Crit. Care Med. 1996;153:861-865.

Yousif A. Lung Cancer In A Sample Of Iraqi Patients , Al-Kindy Col Med J. 2007;4(1):53-9.

Kuriyama K, Rijuhei T, Osamu Doi. CT pathologic correlation in small peripheral lung cancer, AJR. 1987;149:1139-43.

Marvin EN, Dennis KH, Reed D. Pre Operative CT evaluation od Adrenal glands in Non small cell bronchogenic cancer AJR. 1982;139:507-10.

Sandler MA, Seely JM, Mayo JR, Miller RR, Borron M, Pimentel G, et al. CT in the evaluation of the adrenal gland in the pre-operative assessment of Bronchogenic Carcinoma Radiology. 1982;145:733-6.

Faling LJ, Pugatch RD, Jung-Legg Y, Daly BD, Hong WK, Robbins AH. Computed tomographic scanning of the mediastinum in staging of bronchogenic carcinoma. Am.Rev Respiration Dis. 1981;124:690-5.

McLoud TC, Bourgouin PM, Greenberg RK. Bronchogenic carcinoma: analysis of staging in mediastinum with CT by correlative lymph node mapping and sampling Radiology. 1992;182(2):319-23.

Libshitz HI, McKenna RJ. Mediastinal lymph node size in lung cancer AJR Am J Roentgenol. 1984;143(4):715-8.

Primack SL, Lee KS, Logan PM, Miller RR, Muller NL. Bronchogenic carcinoma: utility of CT in the evaluation of patients with suspected lesions. Radiology. 1994;193:795-800.

Naidich DP, Lee JJ, Garay SM, McCauley DI, Aranda CP, Boyd AD. Comparison of CT and fiberoptic bronchoscopy in the evaluation of bronchial disease. Am.J.Roentgenol. 1987;148:1-7.

Gupta RC, Purohit SD, Sharma MP, Bhardwaj S. Primary bronchogenic carcinoma: clinical profile of 279 cases from Midwest Rajasthan. Indian Chest Allied Sciences. 1998;40:109-16.

Jain NK, Madan A, Sharma TN, Agnihotri SP, Saxena A, Mandhana RG. Bronchogenic carcinoma .A study of 109 cases. J Assoc Physicians India. 1989;37(6):379-82.

Rosado-de–Christenson ML, Templeton PA, Moran CA. Bronchogenic carcinoma: radiologic-pathologic correlation. Radiographics. 1994;14:429-46.

Baron LR, Levitt RG, Sagel SS, White MJ, Roper CL, Marbarger JP. CT of the preoperative evaluation of bronchogenic carcinoma. Radiology. 1982:145-57.