Random blood glucose on admission as prognostic factor for assessment of severity of acute myocardial infarction


  • Vibhuti Jain Department of Pathology, Shalby Hospital, Indore, Madhya Pradesh, India
  • Akhlesh Kumar Jain Department of Pathology, Shalby Hospital, Indore, Madhya Pradesh, India




Acute myocardial infarction, Prognosis, Random blood glucose


Background: Assessment of risk factors or prognostic markers is essential to determine the adverse outcome related to acute myocardial infarction (AMI). The aim of the present study was to examine the role of random blood glucose as prognostic marker for assessment of severity of AMI.

Methods: This prospective study was conducted on 79 patients with onset symptoms of AMI. All the patients both diabetics and non-diabetics underwent serum blood glucose estimation in the hospital. Primary endpoint of the study was all cause mortality till day 90 follow-up. The secondary end points were composite of death, reinfarction and heart failure till day 90.Mortality rate is higher in the diabetics as compared to nondiabetics.

Results: The mean age group was 55.9 years. Males (86%) outnumbered females (14%). The mean BMI was 22.3±2.83. The mean random blood glucose in the study population was 138±92.9 mg/dl (7.7±5.15 mol). Of total 79 patients, 5 were diabetics, of them 2 (40%) died. Among 79 patients, 16 patients were died during 3 months following the qualifying event, 7 had heart failure and 4 had reinfarction.

Conclusions: In patients with AMI, hyperglycemia should consider as one of the important prognostic marker to determine the adverse cardiovascular events.


Karetnikova V, Gruzdeva O, Uchasova E, Osokina A, Barbarash O. Glucose levels as a prognostic marker in patients with ST-segment elevation myocardial infarction: a case–control study. BMC Endocr Disord. 2016;16(1):31.

Shihara M. Acute hyperglycemia in patients with acute myocardial infarction. Circulation Journal 2012. Available at: https://acutecaretesting.org/en/journal-scans/hyperglycemia-and-myocardial-infarction. Accessed on 10 October 2016.

Kobalava JD, Tolkachev VV. Hyperglycemia in patients with acute coronary syndrome: state of the art. Scientific Committee's recommendations on diabetes by the American Heart Association. Kardiologiia. 2009;49(3):77-85.

Meier JJ, Deifuss S, Klamann A, Launhardt V, Schmiegel WH, Nauck MA. Plasma glucose at hospital admission and previous metabolic control determine myocardial infarct size and survival in patients with and without type 2 diabetes: the Langendreer Myocardial Infarction and Blood Glucose in Diabetic Patients Assessment (LAMBDA). Diabetes Care. 2005;28(10):2551-3.

Abbate A, Biondi-Zoccai GL. The difficult task of glycaemic control in diabetics with acute coronary syndromes: finding the way to normoglycaemia avoiding both hyper- and hypoglycaemia. Eur Heart J. 2005;26(13):1245-8.

Capes SE, Hunt D, Malmberg K, Gerstein HC. Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview. Lancet. 2000;355(9206):773-8.

Barsheshet A, Garty M, Grossman E, Sandach A, Lewis BS, Gottlieb S, et al. Admission blood glucose level and mortality among hospitalized nondiabetic patients with heart failure. Arch Intern Med. 2006;166(15):1613-9.

Capes SE, Hunt D, Malmberg K, Pathak P, Gerstein HC. Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients: a systematic overview. Stroke. 2001;32(10):2426-32.

Kavanagh BP, McCowen KC. Clinical practice. Glycemic control in the ICU. N Engl J Med. 2010;363(26):2540-6.

Ceriello A. Postprandial hyperglycaemia: a new risk factor for cardiovascular disease. Diabet Metab Heart. 2008;17(5):363-73.

Raguso CA, Helary C, Philippe J. Importance of the postprandial glycemia in the management of type 2 diabetes. Rev Med Suisse. 2008;4(160):1383-6.

Is fasting glucose sufficient to define diabetes? Epidemiological data from 20 European studies. The DECODE-study group. European Diabetes Epidemiology Group Diabetes Epidemiology: Collaborative analysis of Diagnostic Criteria in Europe. Diabetologia. 1999;42(6):654-74.

Ishihara M, Kojima S, Sakamoto T, Asada Y, Tei C, Kimura K, et al. On behalf of the Japanese Acute Coronary Syndrome Study (JACSS) Investigators. Acute hyperglycemia is associated with adverse outcome after acute myocardial infarction in the coronary intervention era. Am Heart J. 2005;150(4):814-20.

Rydén L, Standl E, Bartnik M, Van den Berghe G, Betteridge J, de Boer MJ, et al. Guidelines on diabetes, pre-diabetes and cardiovascular diseases: executive summary. Eur Heart J. 2007;28(1):88-136.




How to Cite

Jain, V., & Jain, A. K. (2019). Random blood glucose on admission as prognostic factor for assessment of severity of acute myocardial infarction. International Journal of Research in Medical Sciences, 7(7), 2639–2643. https://doi.org/10.18203/2320-6012.ijrms20192577



Original Research Articles