Ultrasound of abdomen in acute viral hepatitis and its role as a prognostic marker

Authors

  • Rajveer S. Beniwal Department of Radiodiagnosis, Military Hospital, Mhow, Indore, Madhya Pradesh, India
  • Akhilesh Rao Department of Radiodiagnosis, Command Hospital, Lucknow, Uttar Pradesh, India
  • Yayati Pimpalwar Department of Radiodiagnosis, Command Hospital, Lucknow, Uttar Pradesh, India
  • Prabhakar Teli Department of PSM, AFMC, Pune, Maharashtra, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20195536

Keywords:

Acute viral hepatitis, Prognostic marker, Ultrasound abdomen

Abstract

Background: To assess the extent of Ultrasound (USS) abdomen findings in acute viral hepatitis and further assess the role of USS as a prognostic marker.

Methods: From May 2013 to September 2016, a total of 220 patients of acute Enterogenic viral hepatitis were studied by routine USS within first seven days of onset of symptoms, followed by routine USS between 10 to 15 days and follow up scan after 12 weeks. Only patients with acute Enterogenic viral hepatitis (Hepatitis A and Hepatitis E) were included. All patients with chronic liver disease and other form of acute hepatitis i.e. Hepatitis B, C and D were excluded from the study.

Results: Among 220 patients of acute viral hepatitis routine USS findings including hepatomegaly, bright liver and thickened GB wall and periportal adenopathy were in isolation or in combination up to varying degrees. The commonest routine USS finding in acute phase was thickened GB wall (80%). 14 patients exhibited triad of enlarged Portal Vein (PV), Splenomegaly and Ascites. These 14 patients had prolonged stay in hospital and 11 patients had deranged liver function tests at 12 wks. interval and three patients developed hepatic encephalopathy including one patient who went into fulminant hepatic failure. Out of the patients who did not exhibit this triad 72 patients still had deranged LFT at 12 weeks and maximum of these patients had a combination of USS markers at presentation.

Conclusions: USS has very little if any role in the diagnosis of acute viral hepatitis. It can however play an important role as a prognostic marker during the acute phase where it can detect enlarged portal vein, splenomegaly and ascites. This triad of USS findings is suggestive of transient portal hypertension likely due to hepatic congestion. Also, other USS markers if seen in combination at presentation can reliably predict a poorer prognosis

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References

Kaur R, Gur R, Berry N, Kar P. Etiology of endemic viral hepatitis in urban North India. Southeast Asian J Trop Med Pub Health. 2002;33(4):845-8.

Aggarwal R, Shahi H, Naik S, Yachha SK, Naik SR. Evidence in favour of high infection rate with hepatitis E virus among young children in India. J Hepatol. 1997;26(6):1425-6.

Niederau C, Sonnenberg A. Liver size evaluated by ultrasound: ROC curves for hepatitis and alcoholism. Radiol. 1984;153(2):503-5.

Sudhamsu KC. Ultrasound findings in acute viral hepatitis. Kathmandu Univ Med J. 2006;4:415-8.

Sharma MP, Dasarathy S. Gallbladder abnormalities in acute viral hepatitis: a prospective ultrasound evaluation. J Clini Gastroenterol. 1991;13(6):697-700.

Giorgio A, Amoroso P, Fico P, Lettieri G, Finelli L, de Stefano C, et al. Ultrasound evaluation of uncomplicated and complicated acute viral hepatitis. J Clini Ultrasound. 1986;14(9):675-9.

Zivković R, Trajer A. Ultrasound diagnosis of acute viral hepatitis. Acta medica Croatica: casopis Hravatske akademije medicinskih znanosti. 1998;52(2):109-13.

Ahn JH, Chung JJ, Yu JS, Kim JH, Cho ES, Kim DJ. Prognostic value of gallbladder wall thickening in patients with acute hepatitis A. Ultrasonography. 2015;34(2):139.

Yang SS, Wu CH, Chen TK, Lee CL, Lai YC, Chen DS. Portal blood flow in acute hepatitis with and without ascites: A non‐invasive measurement using an ultrasonic Doppler. J Gastroenterol Hepatol. 1995;10(1):36-41.

Valla D, Flejou JF, Lebrec D, Bernuau J, Rueff B, Salzmann JL, et al. Portal hypertension and ascites in acute hepatitis: clinical, hemodynamic and histological correlations. Hepatol. 1989;10(4):482-7.

Arena U, Vizzutti F, Corti G, Ambu S, Stasi C, Bresci S, et al. Acute viral hepatitis increases liver stiffness values measured by transient elastography. Hepatol. 2008;47(2):380-4.

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Published

2019-11-27

How to Cite

Beniwal, R. S., Rao, A., Pimpalwar, Y., & Teli, P. (2019). Ultrasound of abdomen in acute viral hepatitis and its role as a prognostic marker. International Journal of Research in Medical Sciences, 7(12), 4673–4676. https://doi.org/10.18203/2320-6012.ijrms20195536

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Original Research Articles