Prevalence of chronic complications of type 2 diabetes mellitus in a secondary health centre in Niger Delta, Nigeria


  • Ufuoma Chukwuani Department of Medical Lab Science, Chevron Hospital Warri
  • Kester A. Digban Department of Medical lab Science, College of Health Sciences, Igbinedion University, Okada, Edo
  • Godwin D. Yovwin Department of Family Medicine, Delta State University Teaching Hospital, Oghara, Delta
  • Ngozi J. Chukwuebuni Departments of Internal Medicine, Central Hospital (HMB) Warri, Delta



Niger Delta, Chronic complications, Type 2 diabetes mellitus


Background: Type 2 diabetes mellitus (T2DM) in Nigeria is believed to rapidly be on the increase despite its awareness. Its related chronic complications is also expanding leading to reduction in the quality of life of patients, incurring heavy burdens to the health care system, loss of man hours from work and increasing diabetic mortality. Current information on the prevalence of chronic complications and its related clinical characteristics in Niger Delta area is scarce. The aim of this study was to determine the prevalence of chronic complications of type 2 diabetes mellitus in a secondary health Centre in Niger Delta, with the objective of relating the effect of age and gender with these complications as well as determining their glycemic control.

Methods: 200 consenting adult diabetics 96 (48%) males and 104 (52%) females, who have been attending the diabetic clinics for at least 12 months, were randomly recruited for the study. Hospital records, questionnaire and laboratory investigations were used to collect the demographic, clinical data as well as values of fasting blood sugar, urea, creatinine, lipids, urine microalbumin and glycated hemoglobin for all subjects.

Results: Of the 200 T2DM patients evaluated for chronic complications, 130 (65%) presented with one form of complication varying from nephropathy (58%), dyslipidemia (57%), hypertension (48%), neuropathy (14%) and retinopathy (9%) with 104 (52%) having more than two categories concurrently. chronic complications varied with gender as well as age.

Conclusions: Chronic complications are common among type 2 diabetes in central hospital Warri, Nigeria. Implementation of timely and appropriate screening strategies could decrease the burden of diabetes chronic complications.


Ozougwu JC, Obimba KC, Belonwu CD and Unakalamba, CB. The pathogenesis and pathophysiology of type 1 and type 2 diabetes mellitus. Journal of Physiology and Pathophysiology. 2013;4(4):46-57.

International Diabetes Federation. Diabetes Atlas. 2. Brussels: Gan D, Ed. Belgium; 2003.

Thomas JS. National Diabetes Data Group. Diabetes in America. Bethesda. 2. 1995. Disability in Diabetes [A] NIH Publication NO.9521468.

Roglic G, Unwin N, Bennett PH, Mathers C, Tuomilehto J, Nag S, et al. The burden of mortality attributable to diabetes: realistic estimates for the year 2000. Diabetes Care. 2005;28(9):2130-5.

Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Research and Clinical Practice. 2010;87:4-14.

Wang W, Fu CW, Pan CY, Chen W, Zhan S, Luan R, et al. How do type 2 diabetes mellitus-related chronic complications impact direct medical cost in four major cities of urban China? Value Health. 2009;12(6):923-9.

Chinenye S, Uloko AE, Ogbera AO, Ofoegbu EN, Fasanmade OA, Fasanmade AA, Ogbu OO. Profile of Nigerians with diabetes mellitus - Diabcare Nigeria study group: Results of a multicenter study. Indian J Endocr Meta. 2008;16:558-64.

Akinkugbe OO. Editor. Final Report of National Survey on Non Communicable Diseases in Nigeria. Federal Ministry of Health and Social Services, Lagos. Series. (1997).

Kolawole BA, Abodunde O, Ikem RT, Fabiyi AK. A test of the reliability and validity of a diabetes specific quality of life scale in a Nigerian hospital. Quality of Life Research. 2009;13:1287-95.

Wild S, Roglic C, Green A, Sicrete R, King H. Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care. 2004;27:1047-53.

Okoro EO, AdejumoAO, Oyejola BA. Diabetic care in Nigeria: Report of a self-audit. J Diabet Complications. 2002;16:159-64.

Rotimi CN, Chen G, Oli J, Ofoegbu E, Okafor G Acheampong J et al. A Genome - wide search for Type 2 diabetes susceptibility genes in West Africans. Diabetes. 2004;53:838-41.

World Health Organization: Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications: Report of a WHO Consultation. Part 1: Diagnosis and Classification of Diabetes Mellitus. Geneva, World Health Org., 1999.

Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med. 1998;15(7):539-53.

Daniel WW. Biostatistics: A Foundation for Analysis in the Health Sciences. 7th edition. New York: John Wiley & Sons.1999.

Raabo E, Terkildsen TC. On the enzymatic determination of blood glucose. Scand J Clin Lab. Invest. 1960;12:402-7.

Fabiny DL, Ertingshausen G. Automated reaction – rate method for determination of serum creatinine with the centrifiChem. Clin Chem. 1971;17:696-700.

Talke H, Schubert GE. Enzyme determination of urea in blood serum by the Warburg optical test. Klinische Wochenschrift. 1965;43:174-5.

Allain CC, Poon LS, Chan CS, Richmond W, Fu PC. Enzymatic determination of total serum cholesterol. Clin Chem. 1974;20:470-5.

Fossati P, Prencipe L. Serum triglycerides determination colorimetrically with an enzyme that produces hydrogen peroxide. Clin Chem. 1982;28(10):2077-80.

Benzie I. High density lipoprotein-cholesterol. Med Lab Sci. 1979;36:280-91.

Assmann G, Jabs HU, Kohnert U Nolte W, Schriewer H. LDL-cholesterol determination in blood serum following precipitation of LDL with polyvinylsulfate.. Clin Chem Acta. 1984;140(1):77-83.

Hiar CE. Clinical summary report. Clinical performance of DCA 2000+ hemoglobin AiC system six-minute assay. Bayer Diagnostic Division. 1998;1:1-7.

Barnett K, Mercer SW, Norbury M, Watt G, Wyke S, Guthrie B. Epidemiology of multi-morbidity and implications for health care, research, and medical education: a cross-sectional study.

National Diabetes Prevention and Control Cooperative Group. Chinese guidelines for type 2 diabetes. Beijing: Beijing Science and Technology Press; 2007.

Alebiosu BO. Clinical Diabetic Nephropathy in a Tropical African Population. West Afr J Med. 2007;22:152-5.

Schram MT, Chaturvedi N, Schalkwijk C, Giorgino F, Ebeling P, Fuller JH, et al. (2003).Vascular risk factors and markers of endothelial function as determinants of inflammatory markers in type 1 diabetes. The EURODIAB Prospective Complications Study. Diabetes Care. 2003;26:2165-73.

Liu Z, Fu C, Wang W, Xu B. Prevalence of chronic complications of type 2 diabetes mellitus in outpatients - a cross-sectional hospital based survey in urban China Health. Qual Life Outcomes. 2010;8:62.

Zhang B, Xiang HD, Mao WB, Guo XH, Wang JC, Jia WP, et al. Epidemiological survey of chronic vascular complications of type 2 diabetic in-patientsin four municipalities. Acta Academiae Medicinae Sinicae. 2002;24(5):452-6.

Morgan CL, Currie CJ, Stott NC, Smithers M, Butler CC, Peters JR. The prevalence of multiple diabetes-related complications. Diabet Med. 2000;17(2):146-51.

Heydaria I, Radia V, Razmjoua S, Amirib A. Chronic complications of diabetes mellitus in newly diagnosed patients. International journal of diabetes mellitus.2010;2(1):61-3.

Harzallah F, Ncibi N, Alberti H, Brahim BA, Smadhi H, Kanoun F. Clinical and metabolic characteristics of newly diagnosed diabetes patients: experience of a university hospital in Tunis Diabetes Metab. 2006;32(6):632-5.

Pusley D. Racial and ethnic disparities in renal disease. Kidney Int. 2005;68:1364-5.

Norris KC, Agodoa LY. Unravelling the racial disparity associated with kidney disease. Kidney Int. 2005;68:914-24.

Tang L, Chen X, Chen H, Zhao L, Hu S. The financing burden of treatment of diabetes II and Its symptom in urban China. Chinese Health Economics. 2003;22(12):21-3.

Chen Y, Teng X, Lu S, Liu W. Survey on prevalence of complication in type 2 diabetic outpatients and its related factors. Shandong Med J. 2007;47(17):137-8.

Wandell PE, Gafvels C. Patients with type 2 diabetes aged 35-64 years at four primary health care centres in Stockholm County, Sweden. Prevalence and complications in relation to gender and socio-economic status. Diabetes Res Clin Pract. 2004;63(3):195-203.

Alonso-Morán E, Orueta JF, Esteban JIF, Axpe JMA, González MLM, Polanco NT, et al. The prevalence of diabetes-related complications and multimorbidity in the population with type 2 diabetes mellitus in the Basque Country. BMC Public Health. 2014;14:1059. DOI: 10.1186/1471-2458-14-1059.

Juel K, Christensen K. Are men seeking medical advice too late? Contacts to general practitioners and hospital admissions in Denmark 2005. Journal of public health. 2008;30(1):111-3.

United Kingdom Prospective Diabetes Study (UKPDS) Group. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet. 1998;352:854-65.




How to Cite

Chukwuani, U., Digban, K. A., Yovwin, G. D., & Chukwuebuni, N. J. (2016). Prevalence of chronic complications of type 2 diabetes mellitus in a secondary health centre in Niger Delta, Nigeria. International Journal of Research in Medical Sciences, 4(4), 1080–1085.



Original Research Articles