DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20192479

Role of MRI in evaluation of seizure disorder in Southern Rajasthan, India

Swati Chabarwal, Narendra Kumar Kardam

Abstract


Background: The objectives are to identify and study structural abnormalities in the brain that associated with seizures, spectrum of findings in patients with seizures, classify seizure type and syndrome and to evaluate role of MRI in postoperative seizures.

Methods: A total of 110 patients, those referred from various outdoor/indoor departments with the history of seizure were included after fulfilling the inclusion criteria. Detailed history, appropriate clinical examinations and biochemical investigations were recorded. All MRI scans were performed on a 1.5 T Philips Achieva. Sequences were used according to MR Imaging protocol of seizures. Observation was made and analysed using descriptive tools and scientific methods.

Results: Among 110 patients’ majority (41%) were normal, 20% had cerebral infarct with gliosis followed by NCC 7.2%, atrophy 5.45%, tuberculosis 11%, venous thrombosis 3.64%, developmental malformations 3.64%, glioma 1.82%, cavernoma 1.82%, tuberous sclerosis 1.82%, meningioma 0.91%, cerebral abscess 0.91% and Sturge-weber syndrome 0.91%. Most of the patients with cerebrovascular causes and male predominance  61.8%.

Conclusions: The present study was a prospective study. Spectrum of MRI findings related to vascular, developmental, infection and neoplasm was identified. MRI is noninvasive modality with no radiation hazard, excellent gray white matter resolution and multiplanar imaging capability. MRI helps in detection of subtle lesions responsible for seizures. Present study observed that MRI with appropriate imaging protocols add sensitivity and specificity in evaluation of seizures.


Keywords


Imaging protocol, MRI, Seizures

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References


Harrison’s principle of internal medicine. 19th ed. 2015:2542.

Scott N. Atlas. Magnetic Resonance Imaging of the brain and spine. 4th ed. 2009:2-14.

Goodridge DMG, Shorvon Sd. Epileptic seizures in a population of 6000 demography, diagnosis and classification and role of the hospital services. Br Med J. 1983;287:641-7.

Sander JWAS, Hart YM, Johnson AL, Shorvon SD. National general practice study of epilepsy: newly diagnosed epileptic seizures in a general population. Lancet. 1990;336:1267-71.

Seizures and epilepsy, Lowertein DH in section 2 diseases of the central nervous system, Chapter-348, Harrison’s principles of internal medicine, Kasper DL, Fauci AS, Longo LD, Braunwald E, Houser SL, Jameson JL (edt), 16th ed., Vol. II, New York: McGraw Hill; 2005:2357-2372.

McGahan JP, Dublin AB, Hill RP. The evaluation of seizure disorders by computed tomography. J Neurosurg. 1979;50:328-32.

Kaur S, Garg R, Aggrawal S, Chawla SP, Pal R. Adult onset seizures: Clinical, etiological and radiological profile. J Family Med Prim Care. 2018;7:191-7.

Pannag KN, Ravi N. Magnetic resonance imaging of the brain in adults presenting with new onset seizures. SSRG Int J Med Sci. 2015;2:30‑43.

Muralidhar V, Venugopal K. New onset seizures: Etiology and co‑relation of clinical features with computerized tomography and electroencephalography. J Sci Soc. 2015;42:82‑7.

Hirani MM, Shrivastva S. Clinical profile of new onset seizures in adults. Indian J Appl Res. 2015;5:19‑21.

Sendil G, Kumar AN, Kumar MV. Late onset shake‑etiology at stake - A prospective study. Int J Sci Stud. 2014;2:20‑4.

Jiménez Jiménez FJ, Molina Arjona JA, Zancada F, Santos J, Roldán Montaud A, Fernández Ballesteros A. Etiology of late‑onset epilepsy. A prospective study in an area of rural health care. Med Clin (Barc). 1990;94:521‑4.

Sinha S, Satishchandra P, Kalband BR, Bharath RD, Thennarasu K. Neuroimaging observations in a cohort of elderly manifesting with new onset seizures: Experience from a university hospital. Ann Indian Acad Neurol. 2012;15:273‑80.

Luhdorf K, Jensen LK, Plesnor AM. Etiology of seizures in the elderly. Epilepsia. 1986;27:458-463.

Kanitkar SA, Gaikwad AN, Kalyan M, Aarwal R, Krunal K, Tamakuwala KK, et al. Study of seizure disorder in elderly: Etiology, types, EEG and image findings. Transworld Med J. 2013;1:24‑5.

Quraishi SM, Usha Rani PS, Prasanthi P, Sudhakar P. Etiological profile of new onset seizures. J Evid Based Med Healthc. 2015;2:7032‑44.

Gupta RK. Tuberculosis and other nontuberculous bacterial granulomatous infections. In R. K. Gupta, R.B Lufkin, MR imaging and spectroscopy of central nervous system infection. New York; Kluwer Academic / Plenum Publishers, 2001;95-145.