DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20160790

Role of high resolution computed tomography in evaluation of diffuse lung diseases

Bhuvan Krishna Pingile, Rajitha Kolan, Sravya Vadlamudi, H. R. Nagrale

Abstract


Background: Diffuse lung diseases are those in which the disease process is widespread involving both the lungs but need not affect all lung regions uniformly. Plain chest radiograph though inexpensive, excellent modality of choice, the pattern of diffuse lung disease on radiography is often nonspecific. HRCT can detect normal and abnormal lung interstitium and morphological characteristics of both localized and diffuse lung diseases. The aims and objectives was to study the normal anatomy of the lung with respect to secondary pulmonary lobule; to evaluate the importance of high resolution computed tomography in the diagnosis of diffuse lung diseases; to detect diffuse lung diseases in patients who had normal or questionable radiographic abnormalities with symptoms or pulmonary function tests suggestive of diffuse lung disease; to determine the site of CT guided lung biopsy for  confirmation of diagnosis in suspicious diseases and to study the various patterns of diffuse lung diseases on HRCT.

Methods: A total number of 50 patients with suspected or known interstitial lung disease were studied by high-resolution computed tomography (HRCT) over a period of 24 months.

Results: In the current study the most common cases are of tuberculosis. Next common condition observed was idiopathic pulmonary fibrosis,12 (24%) cases out of 50 cases and most of them were having changes of end stage lung disease and had short lived history during the course of this study, followed by bronchiectasis, pulmonary edema and emphysema.

Conclusions: HRCT is 16% more sensitive in detection of diffuse lung disease abnormalities than chest radiograph in our study.

 


Keywords


Diffuse lung diseases, Secondary pulmonary lobule, Lung interstitium, High resolution computed tomography

Full Text:

PDF

References


Fraser RG, Pare JAP. Diagnosis of diseases.vol.1.1st ed. Philadelphia: Saunders 1970.pg 465-97.

McLoud TC, Carrigton CB, Gaensler EA. Diffuse infiltrative lung disease: A new scheme for description. Radiology. 1983;149:353-63.

Grainger and Allison’s Diagnostic Radiology,Interstitial Lung Disease, Fourth edition,2001,VOL 1 pg no:491.

Zerhouni EA, Naidich DP, Stitik FP Khouri NF, Siegelman SS. Computed Tomographyof pulmonary parenchyma: part-2: Interstitial disease. J Thoracimag. 1985;1(1):54-64.

Lim MK, Im JG, Ahn JM, Kim JH, Lee SK, Yeon KM. Idiopathic pulmonary fibrosis versus pulmonary involvement of collagen vascular disease: HRCT findings. J Korean Med Sci. 1997;12(6):492-8.

Battista G, Zompatori M, Fasano L, Pacilli A, Basile B. Progressive worsening of idiopathic pulmonary fibrosis. High resolution computed tomography (HRCT) study with functional correlation. Radiol Med. 2003;105(1-2):2-11.

Munk PL, Müller NL, Miller RR, Ostrow DN. Pulmonary lymphangitis carcinomatosis: CT and pathologic findings. Radiology. 1988;166(3):705-9.

Storto ML, Kee ST, Golden JA, Webb WR. Hydrostatic pulmonary edema: High resolution CT findings. AJR Am J Roentgenol. 1995;165(4):817-20.

Ribeiro CM, Marchiori E, Rodrigues R, Gasparetto E, Souza AS Jr, Escuissato D, et al. Hydrostatic pulmonaryedema: high-resolution computed tomography aspects. J Bras Pnemol. 2006;32(6):515-22.

Devenyi K, Czirjak L. High resolution computed tomography for the evaluation of lung involvement in 101 patients with scleroderma. ClinRheumatol. 1995;14(6):633-40

Im JG, Itoh H, Shim YS, Lee JH, Ahn J, Han MC, et al. Pulmonary tuberculosis : CT findings in early active disease and sequential change with antitubercuolous therapy. Radiology. 1993(186):653-60.

Cooke JS, Curie DC, Morgan AD, Kerr IH, Delany D, Strickland B, et al. Role of computed tomography in diagnosis of bronchiectasis. Thorax. 1987;(42):272-7.

Grenier P, Maurice F, Musset D, Menu Y, Nahum H. Bronchiectasis- assessment by thin section CT. Radiology. 1986;(161):95-9.

Reid LM. Reduction in bronchial wall subdivision in bronchiectasis. Thorax. 1950;(5):283-6.

Stern EJ, Frank MS. CT of the lungs in patients with pulmonary emphysemas: Diagnosis, quantification and correlation with pathologic and physiologic findings. AJR Am J Roentgenology.1994(162):791-8.

Webb WR, Stein MG, Finkbeiner WE, Im JG, Lynch D, Gamsu G. Normal and diseased isolated lungs: high-resolution CT. Radiology. 1988;166:81-7.

Murata K, Itoh H, Todo G, Kanaoka M, Noma S, Itoh T et al. Centrilobular lesions of the lung: demonstration by high-resolution CT and pathologic correlation. Radiology. 1986;161(3):641-5.

Chan TY, Hansell DM, Rubens MB, du Bois RM, Wells AU. Cryptogenic fibrosingalveolitis and the fibrosingalveolitis of systemic sclerosis: Morphologic differences on computed tomographic scan. Thorax. 1997;52(3):265-70.

Seely JM, Jones LT, Wallace C, Sherry D, Effmann EL . Systemic sclerosis: using high resolution CT to detect lung disease in children. AJR Am J Roentgenol. 1998;170(3):691-7.

Hong SH, Im JG, Lee JS, Song JW, Lee HJ, Yeon KM. High resolution CT findings ofmiliary tuberculosis. J Comput Assist Tomogr. 1998;22(2):220-4.

Voloudaki AE, Tritou IN, Magkanas EG, Chalkiadakis GE, Siafakas NM, Gourtsoyiannis NC et al. HRCT in miliary lung disease. ActaRadiol. 1990;40(4):451-6.