A comparative study of salivary and serum calcium and alkaline phosphatase in patients with osteoporosis

Authors

  • Bijender Kumar Bairwa Department of Biochemistry, National Institute of Medical Sciences and Research, Jaipur, Rajasthan, India
  • Mamta Sagar Department of Biochemistry, National Institute of Medical Sciences and Research, Jaipur, Rajasthan, India
  • R. C. Gupta Department of Biochemistry, National Institute of Medical Sciences and Research, Jaipur, Rajasthan, India
  • Madhuri Gupta Department of Biochemistry, National Institute of Medical Sciences and Research, Jaipur, Rajasthan, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20192539

Keywords:

Calcium and alkaline phosphatase, Osteoporosis

Abstract

Background: This study was undertaken to investigate the changes in salivary and serum calcium and alkaline phosphatase in osteoporosis patients. The objective was to compare the change in serum levels with those in saliva.

Methods: The study was conducted in the department of biochemistry, National Institute of Medical Sciences and Hospital, Shobha Nagar, Jaipur, Rajasthan, India. Subjects were selected from department of orthopedics, National Institute of Medical Sciences and Hospital, Shobha Nagar, Jaipur, Rajasthan, India. At the same time one hundred adult osteoporosis patients confirmed by DEXA were taken. Calcium and alkaline phosphatase were measured in serum and saliva of each patient. The data obtained was statistically analyzed.

Results: Serum calcium has strong positive correlation with salivary calcium (r=0.726) while serum ALP and salivary ALP had weak positive correlation (r =0.453).

Conclusions: Saliva can be used to measure calcium level instead of serum as it is non-invasive, quick and easy method.

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Published

2019-05-29

How to Cite

Bairwa, B. K., Sagar, M., Gupta, R. C., & Gupta, M. (2019). A comparative study of salivary and serum calcium and alkaline phosphatase in patients with osteoporosis. International Journal of Research in Medical Sciences, 7(6), 2412–2416. https://doi.org/10.18203/2320-6012.ijrms20192539

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Original Research Articles