Histopathological spectrum of salivary gland lesions in Ajmer region, Rajasthan, India
DOI:
https://doi.org/10.18203/2320-6012.ijrms20192904Keywords:
Mucoepidermoid carcinoma, Pleomorphic adenoma, Salivary gland lesions, SialadenitisAbstract
Background: There is a wide spectrum of salivary gland lesions with morphological and clinical diversity which makes it a difficult task for histopathological interpretation. Tumours of salivary glands are uncommon accounting for 3-10% of the total tumors of head and neck region and less than one percent of all tumours. The aim of this study was to recognize various histomorphological patterns of salivary gland lesions, their frequency, age, gender and site wise distribution.
Methods: This study was carried out from June 2015 to May 2018 in the department of Pathology, JLN Medical College and associated Group of Hospitals, Ajmer. Total 121 cases of salivary gland lesions were included. Specimens were processed and stained by Hematoxylin and Eosin stain followed by histopathological examination.
Results: Out of total 121 cases, 43.8% were non-neoplastic and 56.2% were neoplastic. In non-neoplastic lesions predominant was chronic sialadenitis (50.9%) followed by mucocele (28.3%) which commonly seen in submandibular gland (47.17%). Among neoplastic cases, 79.4% were benign and 20.6% were malignant lesions. Neoplastic lesions commonly were seen in parotid (75%). Pleomorphic adenoma was the commonest benign tumour (81.4%). Mucoepidermoid carcinoma was the most common malignant salivary tumour. Benign tumours were common in third and fourth decades, whereas malignant tumours were more common in fifth and sixth decades. Male predominance was seen in overall salivary gland lesions.
Conclusions: Histopathological examination is mandatory in the diagnosis of salivary gland lesions because of their wide spectrum of histomorphology.
Metrics
References
Kerr AG. Scott-Brown’s Otolaryngology. 6th ed. vol 5, Oxford; 1997: 1-21.
Mohan H, Tahlan A, Mundi I, Punia RP, Dass A. Non-neoplastic salivary gland lesions: a 15-year study. Eur Arch Otorhinolaryngol. 2011;268(8):1187-90.
Eveson J W, Auclair P, Gnepp DR, El-Naggar AK. Tumours of the salivary glands: Introduction. World Health Organization Classification of Tumours. Pathology and Genetics Head and Neck Tumours. IARC Press Lyon. 2005;9:209
Ellis GL, Auclair PL. Tumors of salivary glands. Armed forces institute of pathology. Washington DC; 1996:135-371.
Vani N V, Ponniah I. The frequency and distribution pattern of minor salivary gland tumors in a government dental teaching hospital, Chennai, India. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontol. 2011;111(1):32-9.
Dave PN, Parikh UR, Goswami HM, Jobanputra GP, Panchal NV, Shah AM. Histopathological Study of Salivary Gland Lesions. Int J Sci Res. 2014;3(1):367-9.
Laishram RS, Kumar KA, Pukhrambam GD, Laishram S, Debnath K. Pattern of salivary gland tumors in Manipur, India : A 10 year study. South Asian J Cancer. 2013;2(4):250-3.
Kumar MA, Kalahasti R, Sekhar KPAC. Histopathological Study of Neoplastic and Non-neoplastic Lesions of Salivary Gland: An Institutional Experience of 5 Years. Int J Sci Stud. 2017;4(12):69-72.
Soni D, Mathur K, Yadav A, Kumar V. Histopathological Spectrum of Salivary Gland Lesions in Tertiary Care Centre at SMS Medical College, Jaipur, Rajasthan. Int J Med Res. 2016;2(2):209-15.
Bandar S, Priyadarshini KV, Avanigadda I, Hanumanthu S, Ramalaxmi PV. Cytohistological study of salivary gland lesions. Sch J App Med Sci. 2016;4(7A):2338-42.
Lopez-Jornet P. Labial Mucocele: A Study of Eighteen Cases. Internet J Dental Sci. 2005;3(2):1-5.
Vargas PA, Gerhard R, Vergílius JF, Filho A, de Castro IV. Salivary gland tumors in a Brazilian population: a retrospective study of 124 cases. Rev Hosp Clín Fac Med S Paulo. 2002;57(6):271-6.
Fonseca FP, De V Carvalho M, P de Almeida O, Rangel AL, Takizawa MCH, Bueno AG, et al. Clinicopathologic analysis of 493 cases of salivary gland tumors in a Southern Brazilian population, Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;114:230-9.
Venugopal M, Devi CP, Deepthi K, Mutte K. The dynamics of diagnosis of salivary gland tumours: histopathology matters. Int J Res Med Sci. 2016;4:1855-61.
Ahmad S, Lateef M, Ahmad R. Clinicopathological study of primary salivary gland tumors in Kashmir, JK Practitioner. 2002;9(4):231-3.
Shrestha S, Pandey G, Pun CB, Bhatta R, Shashi R. Histopathological Pattern of Salivary Gland Tumors. J Pathology of Nepal. 2014;4:520-4.
Amin NS, Shah SA, Prajapati SG, Goswami HM. Histomorphological spectrum of salivary gland tumors in a tertiary care hospital-A retrospective study. Int J Med Sci Public Health. 2017;6:299-302.
Rewusuwan S, Settakom J, Mahanupab P, Salivary gland tumors in Maharaj Nakoorn Chiang Mai hospital: A retrospective study of 198 cases. Chiang Mai Med Bull. 2006;45(2):45-8.
Ayub M, Zahid S, Abbas Z,Shoukat M. Morphological pattern of parotid tumors. J College Physicians Surg. 2008;18(5):274-7.
Bashir S, Mustafa F. Malla HA, Khan AH, Rasool M, Sharma S. Histopathological Spectrum of Salivary Gland Tumors: A 10 Year Experience. Sch J App Med Sci. 2013;1(6):1070-4.
Iqbal MS, Tabassum A, Chatura KR, Malkappa SK, Basavaraja PK. Histomorphological study of salivary gland neoplasms: a 2 year study. J Evolution Med Dental Sci. 2013;2(4):315-32.