DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20193421

Insulin resistance: is it a feedback mechanism or a therapeutic target in type 2 diabetes?

John Thottukadavil Eapen

Abstract


Insulin resistance is an essential pathological condition leading to hyperglycemia of blood, and hence insulin resistance is considered as a therapeutic target. The experimental evidence of studying the effect of naphthalene on Anadara granosa, a bivalve, indicated mitochondrial dysfunction and osmolarity change in them. This communication tries to suggest whether insulin resistance is a feedback mechanism to protect the influx of nutrients into the cells demanding osmoregulation of cells.


Keywords


Electron transport chain inhibitors ,Insulin resistance, Mitochondrial dysfunction process, Type 2 Diabetes

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