Insulin resistance: is it a feedback mechanism or a therapeutic target in type 2 diabetes?


  • John Thottukadavil Eapen Center for Multi-disciplined Research and Development, MEEISATCODE, Dahanu Road, Maharashtra, India



Electron transport chain inhibitors, Insulin resistance, Mitochondrial dysfunction process, Type 2 Diabetes


Insulin resistance is an essential pathological condition leading to hyperglycemia of blood, and hence insulin resistance is considered as a therapeutic target. The experimental evidence of studying the effect of naphthalene on Anadara granosa, a bivalve, indicated mitochondrial dysfunction and osmolarity change in them. This communication tries to suggest whether insulin resistance is a feedback mechanism to protect the influx of nutrients into the cells demanding osmoregulation of cells.


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How to Cite

Eapen, J. T. (2019). Insulin resistance: is it a feedback mechanism or a therapeutic target in type 2 diabetes?. International Journal of Research in Medical Sciences, 7(8), 3202–3205.