Pattern of critical congenital heart disease and their outcome in Northern India: a medical school based study

Authors

  • Mohd Rafiq Lone Department of Pediatrics, SKIMS Medical College, Bemina Srinagar, Jammu and Kashmir, India
  • Mahvish Qazi Department of Gynecology and Obstetrics, GMC Doda, Jammu and Kashmir, India
  • Najmus Saqib Department of Pediatrics, GMC Doda, Jammu and Kashmir, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20192627

Keywords:

CCHD, Echocardiography, Neonates

Abstract

Background: Critical congenital heart disease (CCHD) comprise a group of morphologically heterogeneous disorders which have one thing in common that early surgical or catheter interventional therapy is mandatory to achieve survival. Our aim in this study was to look for pattern of Critical congenital heart disease in a tertiary centre in Northern India.

Methods: Our study was a hospital based prospective study conducted on all patients with suspected congenital heart disease who were brought to neonatology section of a tertiary care hospital. The methods employed for case detection used were clinical examination, pulse oximetry, chest radiograph, electrocardiogram and echocardiography.

Results: Forty two neonates with suspected congenital heart disease were admitted in our NICU (Neonatal intensive care unit) and nine cases of CCHD were diagnosed. Twenty seven cases were having Non Critical cardiac lesions whereas six cases had respiratory illness. Out of nine cases of CCHD seven patients died while two are alive.

Conclusions: With the advent of more screening tools the prevalence of CCHD has increased and the mortality associated with this condition is also very high. It is thus imperative to go for early surgical correction to achieve survival.

References

Payne RM, Johnson MC, Grant JW, Strauss AW. Toward a molecular understanding of congenital heart disease. Circulation. 1995;91(2):494-504.

Druschel C, Hughes JP, Olsen C. Mortality among infants with congenital malformation in New York state 1983-1988. Public health Rep. 1996;111(4):359-65.

Boneva RS, Botto LD, Moore CA, Yang Q, Correa A, Erickson JD. Mortality associated with congenital heart defects in the United States; trends and racial disparities, 1979-1997. Circulation. 2001;103(19):2376-81.

Chang RK. How many infants with critical congenital heart diseases are missed? Circulation. 2007;116(suppl II):II-614.

Limperopoulos C, Majnemer A, Shevell MI, Rohlicek C, RosenBlatt B, Tchervenkov C, Darwish HZ. Predictors of developmental disabilities after open heart surgery in young children with congenital heart defects. J Pediatr. 2002;141(1):51-8.

Wernovsky G, Stiles KM, Gauvreau K, Gentles TL, duPlessis AJ, Bellinger DC, et al. Cognitive development after the Fontan operation. Circulation. 2000;102(8):883-9.

Bellinger DC, Wypij D, Kuban KC, Rappaport LA, Hickey PR, Wernovsky G, et al. Developmental and neurological status of children at 4 years of age after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass. Circulation. 1999;100(5):526-32.

Bellinger DC, Rappaport LA, Wypij D, Wernovsky G, Newburger JW. Patterns of developmental dysfunction after surgery during infancy to correct transposition of the great arteries. J Dev Behav Pediatr. 1997;18(2):75-83.

Limperopoulos C, Majnemer A, Shevell MI, Rosenblatt B, Rohlicek C, Darwish HZ. Functional Limitations in young children with congenital heart defects after cardiac surgery. Pediatrics. 2001;108(6):1325-31.

Forbess JM, Visconti KJ, Hancock-Friesen C, Howe RC, Bellinger DC, Jonas RA. Neurodevelopmental outcome after congenital heart surgery: results from an institutional registry. Circulation 2002;106 (suppl I):195-1102.

Ellerbeck KA, Smith ML, Holden EW, McMenamin SC, Badawi MA, Brenner JI, Kan JS, Hyman SL. Neurodevelopmental outcomes in children surviving d-transposition of the great arteries. J Dev Behav Prediatr. 1998;19(5):335-41.

Samango-Sprouse C, Suddaby EC. Developmental concerns in children with congenital heart disease. Curr Opin Cardiol. 1997;12:91-8.

Wright M, Nolan T. Impact of cyanotic heart disease on school performance. Arch Dis Child. 1994;71(1):64-70.

Brown KL, Ridout DA, Hoskote A, Verhulst L, Ricci M, Bull C. Delayed diagnosis of congenital heart diseases worsens preoperative condition and outcome of surgery in neonates. Heart. 2006;92(9):1298-1302.

Franklin O, Burch M, Manning N, Sleeman K, Gould S, Archer N. Prenatal diagnosis of coarctation of the aorta improves survival and reduces morbidity. Heart. 2002; 87(1):67-9.

Tworetsky W, McElhinney DB, Reddy VM, Brook MM, Hanley FL, Silverman NH. Improved surgical outcome after fetal diagnosis of hypoplastic left heart syndrome Circulation. 2001;103(9):1269-73.

Bull C. Current and potential impact of fetal diagnosis on prevalence and spectrum of serious congenital heart disease at term in the UK. Lancet. 1999;354(9186):1242-47.

Shirazi H, Haider N, Hassan M. Pattern of heart diseases in children. Ann Pak Inst Med Sci. 2008;4(1):50-5.

Rural population (% of total population). Available at: data.worldbank.org/indicator/SP.RUR.TOTL.ZS

Tautz J, Merkel C, Loersch F, Egen O, Hägele F, Thon HM, et al. Implication of pulse oximetry screening for detection of congenital heart defects. Klin Padiatr. 2010; 222(5):291-5

Arlettaz R, Bauschatz AS, Monkhoff M, Essers B, Bauersfeld U. The contribution of pulse oximetry to the early detection of congenital heart disease in newborn. Eur J Pediatr. 2006;165(2):94-8.

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Published

2019-06-28

How to Cite

Lone, M. R., Qazi, M., & Saqib, N. (2019). Pattern of critical congenital heart disease and their outcome in Northern India: a medical school based study. International Journal of Research in Medical Sciences, 7(7), 2553–2557. https://doi.org/10.18203/2320-6012.ijrms20192627

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Original Research Articles