Association of C- reactive protein level and lipid profile in periodontitis and ischemic heart disease in urban population of Malwa region

Priya Joshi; Himanshu Dagor

doi:10.18203/2320-6012.ijrms20193936

Authors

Priya Joshi Department of Oral Medicine & Radiology, Shri Aurobindo College of Dentistry & Postgraduate Institute, Indore, Madhya Pradesh, India
Himanshu Dagor Department of Medicine, Sri Aurobindo Medical College & Postgraduate Institute, Indore, Madhya Pradesh, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20193936

Keywords:

C-reactive protein, Ischemic heart disease, Lipid metabolism, Periodontitis

Abstract

Background: Various studies have explored the relationship between periodontal disease and ischemic heart disease but their result is diverse. This review article is designed to update the relationship among periodontal disease and ischemic heart disease. Hence, the aim of the present study was to assess whether there is a link between periodontal and ischemic heart disease (IHD).

Methods: This study includes 90 subjects, which were divided into 3 groups: 30 subjects -healthy individuals, 30 subjects- having Periodontitis, 30 subjects- suffering from ischemic heart diseases.

Results: The mean OHI-S scores for group 1, 2 and 3 were 0.95±0.60, 2.91±0.90, 1.54±0.74 respectively. CRP level group 2 and 3 were significantly higher than group 1 (p=0.002 and 0.00 respectively) whereas difference between group 2 and 3 was not significantly significant. Lipid profiles, cholesterol, low density lipoprotein (LDL), triglycerides higher in group 2 as compare to 1 and 3. High density lipoprotein (HDL) levels between groups were not significantly different.

Conclusions: Based on findings and other reports Periodontitis could be a predisposing factor for IHD and perhaps there can be an association among both the diseases.

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