A prospective hospital based study of relation between carotid artery intimal medial thickness in patients with type 1 diabetes

Authors

  • Huma Noor Department of General Medicine, SKIMS, Sour, Srinagar, Jammu and Kashmir, India
  • Imran Khan Department of General Medicine, SKIMS, Sour, Srinagar, Jammu and Kashmir, India
  • Iftikhar Bashir Department of Endocrinology, SKIMS, Sour, Srinagar, Jammu and Kashmir, India
  • Feroze Shaheen Department of Radiodiagnosis, SKIMS, Sour, Srinagar, Jammu and Kashmir, India
  • Sabeeha Gul Department of Radiodiagnosis, SKIMS, Sour, Srinagar, Jammu and Kashmir, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20200753

Keywords:

Carotid arterial intimal thickness, Cases, Controls, Prospective hospital based study, Type 1 diabetes mellitus

Abstract

Background: The aim of this study was to found association between Type 1 Diabetes Mellitus and Carotid Arterial Intimal Thickness (CIMT).

Methods: Study design: It was a prospective case control hospital-based study. One hundred type 1 diabetes patient between the age group 3-36 years were taken. The association between type 1 diabetes with CIMT was studied. All the measurements were standardized. 50 age and sex matched controls were taken for comparison.

Results: There is positive correlation between type 1 diabetes and CIMT (p<0.0001). The correlation further extends between duration of diabetes, glycemic control, age of onset, frequency and severity of diabetic related complication with CIMT.

Conclusions: Carotid atherosclerosis as measured by CIMT has definite association with type 1 diabetes.

References

van Swijndregt AD, Gussenhoven EJ, Lancee CT, Rijsterborgh H, de Groot E, van der Steen AF, et al. An in vitro evaluation of the line pattern of the near and far walls of carotid arteries using B-mode ultrasound. Ultrasound Med Biol. 1996 Jan 1;22(8):1007-15.

Urbina EM, Williams RV, Alpert BS, Collins RT, Daniels SR, Hayman L, et al. Noninvasive assessment of subclinical atherosclerosis in children and adolescents: recommendations for standard assessment for clinical research: a scientific statement from the American Heart Association. Hypertension. 2009 Nov 1;54(5):919-50.

Misra A, Chowbey P, Makkar BM, Vikram NK, Wasir JS, Chadha D, et al. Consensus statement for diagnosis of obesity, abdominal obesity and the metabolic syndrome for Asian Indians and recommendations for physical activity, medical and surgical management. JAPI. 2009 Feb;57(2):163-70.

Dalla Pozza R, Beyerlein A, Thilmany C, Weissenbacher C, Netz H, Schmidt H, et al. The effect of cardiovascular risk factors on the longitudinal evolution of the carotid intima medial thickness in children with type 1 diabetes mellitus. Cardio Diabetol. 2011 Dec;10(1):53.

Mogensen CE, Keane WF, Bennett PH, Jerums G, Parving HH, Passa P, et al. Prevention of diabetic renal disease with special reference to microalbuminuria. Kidney Hyperten Diabe Mell. 1996:539-49.

Chambless LE, Heiss G, Folsom AR, Rosamond W, Szklo M, Sharrett AR, et al. Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the Atherosclerosis Risk in Communities (ARIC) Study, 1987-1993. Am J Epidemiol. 1997 Sep 15;146(6):483-94.

Salonen JT, Salonen R. Ultrasound B-mode imaging in observational studies of atherosclerotic progression. Circulation. 1993 Mar;87(3 Suppl):II56-65.

Loh KC, Thai AC, Lui KF, Ng WY. High prevalence of dyslipidaemia despite adequate glycaemic control in patients with diabetes. Annal Acad Med, Singapore. 1996 Mar;25(2):228-32.

Nathan DM, DCCT/Edic Research Group. The diabetes control and complications trial/epidemiology of diabetes interventions and complications study at 30 years: overview. Diabe Care. 2014 Jan 1;37(1):9-16.

Davis PH, Dawson JD, Riley WA, Lauer RM. Carotid intimal-medial thickness is related to cardiovascular risk factors measured from childhood through middle age: The Muscatine Study. Circulation. 2001 Dec 4;104(23):2815-9.

Raitakari OT, Juonala M, Kähönen M, Taittonen L, Laitinen T, Mäki-Torkko N, et al. Cardiovascular risk factors in childhood and carotid artery intima-media thickness in adulthood: the Cardiovascular Risk in Young Finns Study. Jama. 2003 Nov 5;290(17):2277-83.

Oren A, Vos LE, Uiterwaal CS, Grobbee DE, Bots ML. Cardiovascular risk factors and increased carotid intima-media thickness in healthy young adults: the Atherosclerosis Risk in Young Adults (ARYA) Study. Archiv Int Med. 2003 Aug 11;163(15):1787-92.

Abbott RD, Donahue RP, Kannel WB, Wilson PW. The impact of diabetes on survival following myocardial infarction in men vs women: the Framingham Study. Jama. 1988 Dec 16;260(23):3456-60.

Bond MG, Greenland P, Abrams J, Aurigemma GP, Clark LT, Criqui MH, et al Prevention Conference V: Beyond secondary prevention: identifying the high-risk patient for primary prevention: noninvasive tests of atherosclerotic burden: Writing Group III. Circulation. 2000 Jan 4;101(1):E16-22.

Dalla Pozza R, Bechtold S, Bonfig W, Putzker S, Kozlik-Feldmann R, Netz H, et al. Age of onset of type 1 diabetes in children and carotid intima medial thickness. J Clin Endocrinol Metab. 2007 Jun 1;92(6):2053-7.

Urbina EM, Williams RV, Alpert BS, Collins RT, Daniels SR, Hayman L, et al. Non -invasive Assessment of Subclinical Atherosclerosis in Children and Adolescents: Recommendations for Standard Assessment for Clinical Research: A Scientific Statement from the American Heart Association. Hypertension. 2009;54:919-50.

Peppa-Patrikiou M, Scordili M, Antoniou A, Giannaki M, Dracopoulou M, Dacou-Voutetakis C. Carotid atherosclerosis in adolescents and young adults with IDDM: relation to urinary endothelin, albumin, free cortisol, and other factors. Diabe Care. 1998 Jun 1;21(6):1004-7.

Rogowicz-Frontczak A, Araszkiewicz A, Pilacinski S, Zozulinska-Ziolkiewicz D, Wykretowicz A, Wierusz-Wysocka B. Carotid intima-media thickness and arterial stiffness in type 1 diabetic patients with and without microangiopathy. Archiv Med Sci: AMS. 2012 Jul 4;8(3):484.

Osheiba ZF, Mohammed EK, Abo-Eleneen M, Taha A, Al-Sayed R. Carotid intima-media thickness and its relations with the complications in type I diabetic children. J Am Sci. 2014;10:224-30.

Sibal L, Agarwal SC, Home PD. Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes. Diabe, Metab Synd Obes: Targets Therapy. 2011;4:23.

Wagenknecht LE, D’Agostino Jr R, Savage PJ, O’Leary DH, Saad MF, Haffner SM. Duration of diabetes and carotid wall thickness: the Insulin Resistance Atherosclerosis Study (IRAS). Stroke. 1997 May;28(5):999-1005.

Distiller LA, Joffe BI, Melville V, Welman T, Distiller GB. Carotid artery intima–media complex thickening in patients with relatively long-surviving type 1 diabetes mellitus. J Diabe Compli. 2006 Sep 1;20(5):280-4.

Einarson TR, Hunchuck J, Hemels M. Relationship between blood glucose and carotid intima media thickness: A meta-analysis. Cardio Diabetol. 2010 Dec;9(1):37.

American Diabetes Association. Effect of intensive diabetes treatment on carotid artery wall thickness in the epidemiology of diabetes interventions and complications. Epidemiol Diabe Interven Compli (EDIC) ResGroup. Diabe. 1999 Feb 1;48(2):383-90.

Abdelghaffar S, El Amir M, El Hadidi A, El Mougi F. Carotid intima-media thickness: an index for subclinical atherosclerosis in type 1 diabetes. J Tropical Pediatr. 2006 Feb 1;52(1):39-45.

Osheiba ZF, Mohammed EK, Abo-Eleneen M, Taha A, Al-Sayed R. Carotid intima-media thickness and its relations with the complications in type I diabetic children. J Am Sci. 2014;10:224-30.

Krantz JS, Mack WJ, Hodis HN, Liu CR, Liu CH, Kaufman FR. Early onset of subclinical atherosclerosis in young persons with type 1 diabetes. J Pediatr. 2004 Oct 1;145(4):452-7.

Downloads

Published

2020-02-26

How to Cite

Noor, H., Khan, I., Bashir, I., Shaheen, F., & Gul, S. (2020). A prospective hospital based study of relation between carotid artery intimal medial thickness in patients with type 1 diabetes. International Journal of Research in Medical Sciences, 8(3), 908–914. https://doi.org/10.18203/2320-6012.ijrms20200753

Issue

Section

Original Research Articles