Clinical profile of scrub typhus patients in a tertiary care centre in Himachal Pradesh, India

Authors

  • Ritin Sharma Department of Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
  • Roshan Lal Department of Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
  • Sanjay Mahajan Department of Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
  • Satish Chaudhary Department of Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20193652

Keywords:

Acute undifferentiated fever, Chiggers, Comorbidities, Hepatosplenomegaly, Monsoon, Squatting

Abstract

Background: Scrub typhus a zoonotic disease caused by gram negative bacteria O. tsutsugamushi, is endemic in Himachal Pradesh. This illness occurs mainly in monsoon and post monsoon season. study design of  this study was conducted in a tertiary care centre in Himachal Pradesh between July 2015 and June 2016. All the indoor patients with age above 18 years with a diagnosis of scrub typhus were included in this study.

Results: Out of total 180 patients, 130 were female patients. Most patients were in the age group 21-30 (23.3%). All the patients presented with history of fever, but 54 patients presented with high grade fever. Other Most common symptom was chills and rigours (81%), followed by vomiting and headache each 32%, cough 31%. On examination 21% patients had eschar,14% patients had lymphadenopathy. Most number of patients presented in the month of September (51.6%), followed by August (33.3%).

Conclusion: Scrub typhus being an important differential of acute undifferentiated fever in this region, should not be missed by primary care physicians, as once multi organ dysfunction sets in, mortality rate starts rising. So, there is a high need of sensitization of doctors and people about this illness so that early diagnosis and early treatment can be ensured.

References

Parola P, Paddock CD, Raoult D. Tick borne rickettsioses around the world: emerging diseases challenging old concepts. Clin Microbiol Rev. 2005;18(4):719-56.

Sharma A, Mahajan S, Gupta ML, Kanga A, Sharma V. Investigation of an outbreak of scrub typhus in Himalayan region of India. Jpn J Infect Dis. 2005 Aug; 58(4):208-10.

Rathi NB, Rathi AN, Goodman MH, Aghai ZH. Rickettsial diseases in central India: proposed clinical scoring system for early detection of spotted fever. Indian Pediatr. 2011 Nov 1;48(11):867-72.

Sankhyan N, Saptharishi LG, Sasidaran K, Kanga A, Singhi SC. Clinical profile of scrub typhus in children and its association with hemophagocytic lymphohistiocytosis. Indian Pediatr. 2014 Aug 1;51(8):651-3.

Varghese GM, Janardhanan J, Trowbridge P, Peter JV, Prakash JA, Sathyendra S, et al . Scrub typhus in south India: clinical and laboratory manifestations, genetic variability, and outcome. Int J Infect Dis. 2013 Nov 1;17(11):e981-7.

Philomena J, Rangaswami M, Prathiba P. A study on demographic, clinical profile and outcome of scrub typhus. Int J Adv Med. 2016 Aug;3(3):586-90.

Prakash JA, Abraham OC, Mathai E. Evaluation of tests for serological diagnosis of scrub typhus. Trop Doct. 2006;36(4):212-3.

Kumar R, Thakur S, Bhawani R, Kanga A, Ranjan A. Clinical profile and complications of scrub typhus: hospital-based study in sub-himalayan region. J Assoc Physicians India. 2016 Dec;64(12):30-4.

Aung-Thu SW, Phumiratanaprapin W, Phonrat B, Chinprasatsak S, Ratanajaratroj N. Gastrointestinal manifestations of septic patients with scrub typhus in Maharat Nakhon Ratchasima Hospital. Southeast Asian J Trop Med Public Health. 2004;35(4):845-51.

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Published

2019-08-27

How to Cite

Sharma, R., Lal, R., Mahajan, S., & Chaudhary, S. (2019). Clinical profile of scrub typhus patients in a tertiary care centre in Himachal Pradesh, India. International Journal of Research in Medical Sciences, 7(9), 3266–3269. https://doi.org/10.18203/2320-6012.ijrms20193652

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Section

Original Research Articles