Evaluate the effect of oat-beta glucan in controlling blood glucose levels among type 2 diabetic individuals

Ahmad Abdulualrazag Ali Albalawi, Fatmah Abdulrazzaq Ali Albalawi


Diabetes mellitus (DM) is a metabolic disorder characterized by inappropriate hyperglycemia due to deficiency in producing insulin or inefficient action of this hormone. Patients with DM are frequently afflicted with ischemic vascular disease, wound healing defect, vascular alterations, myocardic infarction, nephropathies, retinopathies and neuropathies. The uses of hypoglycemic agents or insulin are the common conventional treatments of diabetes. However, the frequent use of such expensive medications increased the financial burden upon patients. Low glycaemic food consumption is a very fruitful alternative in controlling diabetes. Foods that are rich in fiber are on the top of the glycaemic index and the potential component is beta glucan. The evidence of consuming oat beta-glucan to enhance glycaemia and insulin levels is not well established. So, the objective of this overview review is to evaluate the effect of oat-beta glucan in controlling blood glucose levels among type 2 diabetic individuals.


Oat beta-glucan and type 2 diabetes, Beta glucan and diabetes, Oat beta glucan and blood glucose

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Kolluru GK, Bir SC, Kevil CG. Endothelial dysfunction and diabetes: effects on angiogenesis, vascular remodeling, and wound healing. Int J Vasc Med. 2012;2012:918267.

Andrade EF, Lobato RV, de Araújo TV, Gilberto M, Zangerônimo RVdS, Pereira LJ. Effect of beta-glucans in the control of blood glucose levels of diabetic patients: a systematic review. Nutr Hosp. 2015;31(1):170-7.

Cugnet-Anceau C, Nazare JA, Biorklund M, Le Coquil E, Sassolas A, Sothier M et al. A controlled study of consumption of β-glucan-enriched soups for 2 months by type 2 diabetic free-living subjects. British journal of nutrition. 2010;103(03):422-8.

Jenkins A, Jenkins D, Zdravkovic U, Würsch P, Vuksan V. Depression of the glycemic index by high levels of beta-glucan fiber in two functional foods tested in type 2 diabetes. Eur J Clin Nutr. 2002;56(7):622-8.

Gajdošová A, Petruláková Z, Havrlentová M, Červená V, Hozová B, Šturdík E et al. The content of water-soluble and water-insoluble β-D-glucans in selected oats and barley varieties. Carbohydrate polymers. 2007;70(1):46-52.

Chen J, Raymond K. Beta-glucans in the treatment of diabetes and associated cardiovascular risks. Vasc Health Risk Manag. 2008;4(6):1265-72.

Lattimer JM, Haub MD. Effects of dietary fiber and its components on metabolic health. Nutrients. 2010;2(12):1266-89.

Reyna NY, Cano C, Bermúdez VJ, Medina MT, Souki AJ, Ambard M et al. Sweeteners and beta-glucans improve metabolic and anthropometrics variables in well controlled type 2 diabetic patients. Am J Ther. 2003;10(6):438-43.

Health Benefits of Barley. The Whole Grains Council. 2016 [cited 30 April 2016]. Available from: whole-grains-101/ health-benefits-of-barley.

Petrisor B, Bhandari M. The hierarchy of evidence: levels and grades of recommendation. Indian J Orthop. 2007;41(1):11-5.

Barnard M, Mulnier H, Noble L, Potts H, Reid A. Co-creating Health phase 2 joint local evaluation (Type 2 diabetes). 2013.

Umpierre D, Ribeiro PA, Kramer CK, Leitão CB, Zucatti AT, Azevedo MJ et al. Physical activity advice only or structured exercise training and association with HbA1c levels in type 2 diabetes: a systematic review and meta-analysis. Jama. 2011;305(17):1790-9.

Regand A, Chowdhury Z, Tosh SM, Wolever TM, Wood P. The molecular weight, solubility and viscosity of oat beta-glucan affect human glycemic response by modifying starch digestibility. Food Chem. 2011;129(2):297-304.

Beck EJ, Tapsell LC, Batterham MJ, Tosh SM, Huang X-F. Increases in peptide YY levels following oat β-glucan ingestion are dose-dependent in overweight adults. Nutr Res. 2009;29(10):705-9.

Holm J, Björck I. Bioavailability of starch in various wheat-based bread products: evaluation of metabolic responses in healthy subjects and rate and extent of in vitro starch digestion. The American journal of clinical nutrition. 1992;55(2):420-9.