Consensus statement on the management of invasive candidiasis in Indian scenario

Authors

  • Prakash Shastri Department of Critical Care and Emergency Medicine, Sir Ganga Ram Hospital, Delhi, India
  • Vivek Nangia Department of Pulmonology, Fortis Hospital, Noida, Uttar Pradesh, India
  • Prachee Sathe Department of Critical Care Medicine, Ruby Hall Clinic, Pune, Maharashtra, India
  • Rajesh Pande Department of Critical Care and Emergency Medicine, BLK Hospital, Delhi, India
  • Abi Abraham Department of Nephrology and Renal Transplant services, Lakeshore Hospital, Kochi, Kerela, India
  • Ashit Hegde Department of Critical Care, PD Hinduja Hospital, Mumbai, Maharashtra, India
  • Abdul Samad Ansari Department of Critical Care, Nanavati Super Speciality Hospital, Mumbai, Maharashtra, India
  • Dharmesh Kapoor Department of Gastroenterology, Global Hospitals, India
  • Amit Mandal Department of Critical Care, Pulmonology and Sleep Medicine, Fortis Healthcare, Punjab, India
  • Alok Jain Department of Nephrology, Rukmani Birla Hospital, Jaipur, Rajasthan, India
  • M. Dinaker Department of Medicine, Sunshine Hospital, Hyderabad, India
  • Deepali Mohanty Department of Medicine, Sahara Hospital, Lucknow, Uttar Pradesh India
  • Dimbeshwar Das Department of Medicine, ILS Hospital, Kolkata, India
  • Venkat Ramana Kola Department of Critical Care, Care Hospital, Ahmedabad, India
  • Sharmili Sinha Department of Critical Care, Apollo Hospital Bhubaneshwar, Odisha, India
  • Amitav Mohanty Department of Medicine and Critical Care, Apollo Hospital Bhubaneshwar, Odisha, India
  • Hardev Singh Girn Department of Liver Transplant, Dayanand Medical College and Hospital, Punjab, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20195028

Keywords:

Candida strains, Caspofungin, Invasive candidiasis, Non-culture tests, Matrix assisted laser desorption/ionization- time of flight

Abstract

Invasive fungal infections in critically ill patients are associated with increased morbidity and mortality. Candida species are among the most common causes of nosocomial bloodstream infections and of invasive infections in intensive care units (ICUs). The high mortality mandates early identification of invasive candidiasis which is vital to initiate appropriate and timely treatment and improve outcomes. Delaying the initiation of treatment could result in an increase in mortality which can be avoided by usage of more rapid diagnostic techniques. There are multiple diagnostic tests including culture and non-culture tests like 1,3-β-D-glucan and newer techniques like MALDI-TOF which are available to diagnose candidemia but each with their drawbacks. Additionally, there are various guidelines like IDSA and ESCMID on treatment which aim to minimize death, late complications from deep-seated candidiasis and rise of drug- resistant Candida strains. Through this consensus statement prepared by a panel of experts, all of whom are senior intensivists, infectious disease specialists and microbiologists, we aim to address the major aspects of management of invasive candidiasis in the Indian population as per the authors opinions, backed by published evidence and supported by the latest clinical guidelines.

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Published

2019-10-24

How to Cite

Shastri, P., Nangia, V., Sathe, P., Pande, R., Abraham, A., Hegde, A., Ansari, A. S., Kapoor, D., Mandal, A., Jain, A., Dinaker, M., Mohanty, D., Das, D., Kola, V. R., Sinha, S., Mohanty, A., & Girn, H. S. (2019). Consensus statement on the management of invasive candidiasis in Indian scenario. International Journal of Research in Medical Sciences, 7(11), 4410–4415. https://doi.org/10.18203/2320-6012.ijrms20195028

Issue

Vol. 7 No. 11 (2019): November 2019

Section

Review Articles