Seborrhoeic keratosis with autosomal dominant inheritance - a rare case report

V. N. S. Ahamed Shariff, L. Balamurugan, N. Saravanan


Seborrhoeic keratosis is a benign tumour composed of epidermal keratinocytes, displaying varying morphological features, frequently pigmented and more common in the elderly. Various clinical and histopathological variants have been described. A genetically determined predisposition to Seborrhoeic keratosis is largely accepted. We report a case of multiple Seborrhoeic keratoses of childhood onset and transmitted for three generations in her family members as an autosomal dominant trait.


Autosomal dominant inheritance, Childhood onset, Multiple seborrhoeic keratoses

Full Text:



Narasimha A, Kumar HML, Divyarani MN, Bhaskaran A. A Pigmented Seborrheic Keratosis (Melanoacanthoma) of Nipple: A case report with review of literature. J Clin Biomed Sci. 2013;3(2):96-100.

Madan V, Lear JT. Benign Keratinoytic Acanthomas and Proliferations. Rook’s Textbook of Dermatology, Ninth Edition. WILEY Blackwell publications: 2016;133:1-5.

Ru-zhi Zhang, Wen-yuan Zhu. Seborrheic keratoses in five elderly patients: An appearance of raindrops and streams. Ind J Dermato. 2011;56(4):432-4.

Rajesh G, Thappa DM, Jaisankar TJ, Chandrashekar L. Spectrum of seborrheic keratoses in south Indians: A clinical and dermoscopic study. Indian J Dermatol Venereol Leprol. 2011;77:483-88.

Bhuiyan ZH. Seborrheic Keratosis: A case report. Orion Med J. 2007;26:441-2.

Rongioletti F, Corbella L, Rebora A. Multiple familial Seborrhoeic Keratoses. Dermatologica 1988;176:43-5.

David G, Abe Dorevitch, Robin M. The prevalence of Seborrhoeic keratoses in people aged 15-30 yrs: Is the term senile keratoses redundant. Arch Dermatol. 2000;136(6):759-62.

Thomas VD, Snavely NR, Lee KK, Swanson NA. Benign Epithelial Tumors, Hamartomas, and Hyperplasias. Fitzpatrick dermatology in general medicine, Eighth edition. McGraw Hill Publications. 2012;1319-23.

Gurucharan S, Prathima KM. Extensive seborrhoiec keratoses mimicking deep mycoses. Ind Dermato Online J. 2011;2:2.

Alapatt GF, Bhat RM, Dandekeri S, Rebello MS. Giant seborrhoeic keratosis with a new dermoscopic finding. Ind J Dermatopatho Diag Dermato. 2015;2(2).