A comparative analysis of total haemoglobin level and red blood cells count in ABO blood groups of healthy adults

Bibhupada Mahapatra, Aurobinda Chinara, Prasanta Purohit


Background: The haemoglobin content and red blood cells counts in four different ABO blood groups in healthy adults remain conflicting with different results. The present study was undertaken to analyse the possible differences in the haemoglobin content and red blood cell counts in health adults in four ABO blood groups.

Methods: This prospective study was undertaken in a tertiary health care facility. A total of 227 healthy students were finally included in this study for analysis. The study subjects were belonging to 18-22 years old of both genders. The haemoglobin content was measured by Sahli’s method and ABO blood group typing along with Rh D typing was carried out in all the students. The statistical analyses were carried out by using Graph-Pad Instat.

Results: The mean age of the students was 19.91 years with 59.9% being males. Both haemoglobin level and red blood cells counts were significantly high in males compared to females. Blood groups A, B, AB and O was reported in 41(18.06%), 63(27.75%), 15(6.60%) and 108(47.58%) healthy students respectively.

conclusion: There was no significant difference was observed in the mean haemoglobin level and red blood cells counts among the four ABO blood groups.


ABO blood group, Haemoglobin, Red blood cells, Rh D typing

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Pramanik T, Pramanik S. Distribution of ABO and Rh blood groups in Nepalese Medical Students: a report. East Mediterr Health J. 2000;6(1):156-8.

Conteras M, Lubenko A. Immunohaematology: introduction. Postgraduate haematology. London, UK: Arnold Publishers. 2001:165-81.

Schneider RG, Hightower B, Hosty TS, Ryder H, Tomlin G, Atkins R, et al. Abnormal hemoglobins in a quarter million people. Blood. 1976;48(5):629-37.

Knowles S, Poole G. Human blood group systems. In: Murphy MF and Pamphilon DH eds. Practical transfusion medicine. Blackwell Science. 1st ed. London, UK; 2002: 24-31.

Jeremiah ZA. Abnormal haemoglobin variants, ABO and Rh blood groups among student of African descent in Port Harcourt, Nigeria. Afric Health Sci. 2006;6(3):177-81.

Ukaejiofor EO; Okonkwo WC; Tagbar EN, Emeribe AO. ABO and Rhesus in a Nigerian population. In: Ukaejiofor EO. Blood Transfusion in the Tropics Salem Press. Nigeria; 1996: 1-22.

Jeremiah ZA, Buseri FI. Rh antigens and phenotype frequencies and probable genotypes for the four main ethnic groups in Port Harcourt Nigeria. Immunohematol. 2003;19(3):86-8.

Wintrobe MM. 'Clinical Hematology' 7th Edition. Philadelphia: Lea and Febiger; 1975: 114-5.

Dukes PP, Goldwasser E. Inhibition of erythropoiesis by estrogens. Endocrinol. 1961;69(1):21-9.

Rishpon-Meyerstein N, Kilbridge T, Simone J, Fried W. The effect of testosterone on erythropoietin levels in anemic patients. Blood. 1968 Apr 1;31(4):453-60.