Coronary angiographic profile characteristics in young patients with acute coronary syndrome and comparison with older patients with acute coronary syndrome

Rakesh K. Maurya, Satish L., Sanjeev Sanghvi, Goutam K


Background: CAD is a major cause of death worldwide. Indians are prone as a community to CAD at much younger age. This study examined the coronary angiographic profile characteristic in young (<40 year) patients with ACS compared with that in older patients (>60 year).

Methods: 192 patients with ACS aged less than 40 year and 200 patients with ACS aged more than 60 year were included in this study. Coronary angiographic profile characteristics were evaluated in young ACS patients and compared with that in older patients.

Results: Young ACS patients often had angiographically normal coronary arteries, nonobstructive disease and single vessel disease than older patients (p value<0.05).

Conclusions: Angiographically normal coronary arteries, nonobstructive disease, single vessel disease are more frequent in younger patients.


Coronary artery disease, Acute coronary syndrome

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Enas EA, Garg A, Davidson MA, Nair VM, Huet BA, Yusuf S. Coronary heart disease and its risk factors in the first generation immigrant Asian Indians to the United States of America. Indian Heart J. 1996;48:343-54.

Enas EA, Salim Yusuf. Third Meeting of the International Working Group on Coronary Artery Disease in South Asians. Indian Heart J. 1999;51: 99-103.

Gupta R. Epidemiological evolution and rise of coronary heart disease in India. South Asian J Preventive Cardiology. 1997;1:14-20.

Enas EA. High rates of CAD in Asian Indians in the United States despite intensive modification of life style. What next. Current Science. 1998;74(12):1081-6.

Janus ED, Postiglione A, Singh RB, Lewis B. The modernization of Asia: Implications for coronary heart disease. Circulation. 1996;94:2671-3.

McKiegue PM, Ferrie JE, Pierpoint T, Marmot MG. Association of early-onset coronary heart disease in South Asians men with glucose intolerance and hyperinsulinemia. Circulation. 1993;87:152-61.

Cole JH, Miller JI 3rd, Sperling LS, Weintraub WS. Longterm follow-up of coronary artery disease presenting in young adults. J Am Coll Cardiol. 2003;41:521-8.

Doughty M, Mehta R, Bruckman D, Das S, Karavite D, Tsai T, et al. Acute myocardial infarction in the young – The University of Michigan experience. Am Heart J. 2002;143(1):56-62.

Fournier JA, Sanchez A, Quero J, Fernandez-Cortacero JA, Gonzalez-Barrero A. Myocardial infarction in men aged 40 years or less; a prospective clinical-angiographic study. Clinical Cardiology. 1996;19:631-6.

Zimmerman FH, Cameron A, Fisher LD, Ng G. Myocardial infarction in young adults: Angiographic characterization, risk factors and prognosis (Coronary Artery Surgery Registry). J Am Coll Cardiol. 1995;26(3):654-61.

Wei JY, Bulkley BH. Myocardial infarction before age 36 years in women: Predominance of non-atherosclerotic events. Am Heart J. 1982;3(104):561-6.

Waters DD, Halphen C, Theroux P, Paul-Robert D, Mizgala HF. Coronary artery disease in young women: clinical and angiographic features and correlation with risk factors. Am J Cardiol. 1978;42:41-7.

Betriu A, Pare JC, Sanz GA, Casals F, Magriña J, Castañer A, et al. Myocardial infarction with normal coronary arteries: a prospective clinical-angiographic study. Am J Cardiol. 1981;48:28-32.

Sanz G, Castaner A, Betriu A, et al. Determinants of prognosis in survivors of myocardial infarction. N Engl J Mcd. 1982;306:1065-70.

Turner JD, Rogers WJ, Mantle JA, Rackley CE, Russel RO Jr. Coronary angiography soon after myocardial infarction. Chest. 1980;77:58-64.

Burkart F, Salzmann C. Angiographic findings in post-infarction patients under the age of 35. In ref. 2:56-60. 4.

Wolfe MW, Vacek JL. Myocardial infarction in the young. Chest. 1988;94:926-30.

Gohlke H, Sturzenhofecker P, Thilo A, Droste C, Gornandt L, Roskamm H. Coronary angiographic findings and risk factors in postinfarction patients under the age of 40. 1981: 61-77.