Published: 2019-11-27

Prevalence of coronary artery diseases in type 2 diabetic women

C. Mandava Radha Mani, Nakkina Bhavani Prasad, Raghavendra Prasad Adda, T. Jaya Chandra


Background: There was increasing evidence that gender differences are important in epidemiology, treatment and outcomes of many diseases, relevant for non-communicable diseases.

Methods: Study was conducted in Department of General Medicine, GSL Medical College. Patients who were admitted with type 2 diabetes were recruited in the study. Each patient was interviewed to obtain detailed history and examined thoroughly as per predetermined protocol, national diabetes data group and WHO diagnostic criteria was used. Myocardial infarction was diagnosed by convex ST segment elevation in corresponding leads (early) or QS complexes or abnormal Q waves i.e. Q waves of 0.04 seconds or more in width (or) 25% or more of the voltage of the R wave in the same lead or both in the corresponding leads (late) or T wave inversion in the corresponding leads (late). Statistical analyses were done by using SPSS software version 21.0. Chi-square test was used to assess the association between different categorical variables; p<0.05 was considered statistically significant.

Results: Out of 250 participants, 97 were diagnosed as coronary artery disease (CAD), maximum between 51-60 years age group; the difference was statistically significant (p<0.05). The association between dyslipidemia and CAD was statistically significant (p<0.05). Out of 188 post-menopausal cases, CAD was diagnosed in 86 cases; out of the 62 non post-menopausal cases, CAD was diagnosed in 11 cases; The difference was statistically significant (p<0.05).

Conclusions: In premenopausal women, the prevalence of CHDs are significantly higher when compared to postmenopausal women.


Diabetes, Disease, Patient, Women

Full Text:



WHO Library Cataloguing-in-Publication Data Global report on diabetes. Available at:;jsessionid=40045B67340AA3168134C573F226D287?sequence=1. Accessed 15 July 2019.

L. Guariguata, D.R. Whiting, I. Hambleton, J. Beagley, U. Linnenkamp. Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes research and clinical practice 2014; 103 (2): 137-49.

Mansour M Al-Nozha, Hussein M Ismail, Omar M A, l Nozha. Coronary artery disease and diabetes mellitus. J Of Taibah University Medical Sciences 2016; 11 (4): 330-8.

Alexandra Kautzky-Willer. Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus. Endocr Rev. 2016; 37(3): 278-316.

Dennis Kasper, Anthony Fauci, Stephen Hauser, Dan Longo, J. Larry Jameson, Joseph Losc. Harrison's Principles of Internal Medicine, 19th ed. New York, NY: McGraw-Hill; 2015: 2215-2229.

Clinical Update: Cardiovascular Disease in Diabetes Mellitus Atherosclerotic Cardiovascular Disease and Heart Failure in Type 2 Diabetes Mellitus – Mechanisms, Management, and Clinical Considerations Cecilia C. Low Wang; Connie N. Hess, 2016;133:2459-2502.

Matthew J. Budoff, Paolo Raggi. Noninvasive cardiovascular risk assessment of the asymptomatic diabetic patient. The Imaging Council of the Am College Cardiol. 2016;9(2):176-92.

Sandeep Chopra, Soumia Peter. Screening for coronary artery disease in patients with type 2 diabetes mellitus: An evidence-based review. Indian J Endocrinol Metab. 2012; 16(1): 94-101.

Viswanathan Mohan, Viknesh Prabu Anbalagan. Expanding role of the Madras Diabetes Research Foundation - Indian Diabetes Risk Score in clinical practice Indian J Endocrinol Metab. 2013; 17(1): 31 -6.

Gupta R, Gupta VP, Sarna M, Bhatnagar S, Thanvi J, Sharma V. Prevalence of CHD and risk factors in an urban Indian population: Jaipur Heart Watch2. Indian Heart J. 2002; 54(1): 59-66.

Arvind Gupta, Rajeev Gupta, Krishna Kumar Sharma, Sailesh Lodha. Research Prevalence of diabetes and cardiovascular risk factors in middle-class urban participants in India BMJ Open Diabetes Res Care. 2014; 2(1): e000048.

Meenakshi Sharma, Nirmal Kumar GangulyVasc Health Risk Manag. Premature coronary artery disease in Indians and its Associated Risk Factors. 2005; 1(3): 217-25.

Martín-Timón. Type 2 diabetes and cardiovascular disease: Have all risk factors the same strength? World J Diabetes. 2014; 5(4): 444-70.

Lu Yihua, G Nabel, Eugene Braunwald, Elizabeth. A Tale of Coronary Artery Disease and Myocardial Infarction. N Engl J Med 2012; 366:54-63.