DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20195887

Evaluation of selected trace elements in the Moroccan type 2 diabetic patients

Naoual El Omri, Fadwa Mekouar, Naoufal Assoufi, Abdelkhalek Maaroufi, Jihane Smaali, Amal Charef, Mohammed Jira, Jamal Fatihi, Rachid Eljaoudi

Abstract


Background: Several trace elements have been implicated in the etiology of type 2 diabetes, they can influence the onset or pathogenesis of diabetes in various ways including disruption of normal metabolism of glucose and insulin. The purpose of this work is to evaluate the serum status of copper, zinc, selenium, chromium and manganese in Moroccan type 2 diabetics compared to control group.

Methods: Blood samples from 100 type 2 diabetics and 90 control subjects were analyzed for blood glucose, glycated hemoglobin (only for diabetics), lipid status and serum trace elements concentrations.

Results: Glucose and triglyceride values were statistically higher in diabetics; while those of HDL-cholesterol were lower. Concentrations of zinc, selenium, chromium, and manganese were lower in diabetics compared to controls. In contrast, copper concentrations were higher.

Conclusions: The status of trace elements is impaired in type 2 diabetics compared to a control group.


Keywords


Chromium, Copper, Manganese, Selenium, Type 2 diabetes, Zinc

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