Frequency and distribution of ABO and Rh blood groups among blood donors in tertiary care hospital of South Gujarat, India
DOI:
https://doi.org/10.18203/2320-6012.ijrms20164213Keywords:
ABO & Rh blood group, Blood donor, GeneAbstract
Background: Since it was discovered by Karl Landsteiner, the ABO blood group system is the most important blood group system in Transfusion Medicine. The blood group systems are also very important in population genetic studies, researching population migration patterns as well as resolving certain medico-legal issues, particularly disputed parentage. This study was carried out with an objective to provide data regarding gene frequency and distribution of ABO and Rh blood groups among blood donors in South Gujarat, India.
Methods: Data of 40732 blood donors were retrospectively collected and analyzed regarding ABO and Rh blood groups from May-2011 to April-2016 and reported in simple numbers and percentage. Blood group of the blood donors was determined by forward and reverse methods with the help of commercially available standard monoclonal antisera by test tube and column agglutination techniques in required cases.
Results: The most common blood group among donors was B (34.43%) followed by O (32.26%), A (24.35%), while the least prevalent blood group was AB (8.94%). Rh positivity among donors was (95.12%). Rests were Rh Negative (4.87%). The estimated gene frequencies were 0.1844 for IA (p), 0.2477 for IB (q) and 0.5679 for IO (r).
Conclusions: The most common blood group in donors was B positive and least common was AB negative.
References
Farhud D, Marjan Z. A Brief History of Human Blood Groups. Iran J Publ Heal. 2013;42(1):1-6.
Blaney K, Howard P. Basic and applied concepts of Blood banking and transfusion practices. 3rd edition. Mosby, elsevier inc. 2013.
Sharma DC, Sunita R, Iyenger S, Jain B, Sao S. Prevalence and distribution of ABO and Rh-D antigens along with its subgroups & rare types in Greater Gwalior Region. Open J Blood Dis. 2013;3:69-73.
Pourazar A. Red cell antigens: Structure and function. Asian J Transfus Sci. 2007;1(1):24-32.
Worlledge S, Ogiemudia S, Thomas C, Ikoku B, Luzzuto L. Blood group antigens and antibodies in Nigeria. Ann Trop Med Parasitology. 1994;68(3):249-64.
Gadwalkar S, N Sunil Kumar, Ravidhar. Distribution of blood groups in and around Bellary, Karnataka. Indian J Clin Pract. 2008;24(3):247-50.
Enosolease M, Bazuaye G. Distribution of ABO and Rh-D Blood group in the Benin area of Niger- Delta: Implication for regional blood transfusion. Asian J Transfus Sci. 2008;2(1):3-5.
Agrawal A, Tiwari AK, Mehta N, Bhattacharya P, Wankhede R, Tulsiani S, et al. ABO and Rh (D) group distribution and gene frequency; the first multicentric study in India. Asian J Transfus Sci. 2014;8(2):121-5.
Chandra T, Gupta A. Frequency of ABO and rhesus blood groups in blood donors. Asian J Transfus Sci. 2012;6:52-3.
Nanu A, Thapliyal R. Blood group gene frequency in a selected north Indian population. Indian J Med Res. 1997;106:242-6.
Sidhu S. Distribution of the ABO blood groups and Rh(D) factor among the scheduled caste population of Punjab. Anthropol. 2003;5(3):203-4.
Rajshree B, Raj JY. Distribution of ABO blood group and Rh (D) factor in Western Rajasthan. Nat J Med Res. 2012;3(1):73-5.
Gupta NK, Dadwal S. Distribution of ABO and Rhesus-D blood groups. Asian J Trans Sci. 2012;6(1):73.
Ipsita N, Sekhar S. ABO and Rhesus blood groups in potential blood donors at Durgapur Steel city of the district of Burdwan, West Bengal. Asian J Transfus Sci. 2012;6(1):54.
Periyavan S, Sangeetha S, Marimuthu P, Manjunath B, Seema D. Distribution of ABO and Rhesus-D blood groups in and around Bangalore. Asian J Transfus Sci. 2010;4(1):41.
Dass P, Nair S, Harris V, Rose D, Mammen J, Bose Y, et al. Distribution of ABO and Rh-D blood groups among blood donors in a tertiary care centre in South India. Trop Doct. 2001;31(1):47-8.
