Published: 2019-12-25

Bilateral idiopathic granulomatous mastitis a rare benign inflammatory disease of breast: case report

Talib Hussain, Subash Bhardwaj


Idiopathic Granulomatous Mastitis (IGM) is an uncommon benign inflammatory disorder of breast. Peri-ductal mastitis is thought to be the initial inflicting factor for its development. IGM usually presents as painful swelling, abscess or sinus/fistula in breast. There are no specific findings on ultrasound or mammographic imaging, and moreover it looks BIRADS-IV on mammography. Histopathology provides the final diagnosis. Here authors report a case of bilateral IGM which was successfully treated with surgery.


Fine needle aspiration cytology, Histopathological examination, Idiopathic granulomatous mastitis, Nipple areola complex

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Kessler E, Wolloch Y. Granulomatous mastitis: a lesion clinically simulating carcinoma. Am J Clin Pathol. 1972 Dec 1;58(6):642-6.

Gurleyik G, Aktekin A, Aker F, Karagulle H, Saglamc A. Medical and surgical treatment of idiopathic granulomatous lobular mastitis: a benign inflammatory disease mimicking invasive carcinoma. J Breast Cancer. 2012 Mar 1;15(1):119-23.

Patel RA, Strickland P, Sankara IR, Pinkston G, Many W, Rodriguez M. Idiopathic granulomatous mastitis: case reports and review of literature. J General Int Med. 2010 Mar 1;25(3):270-3.

Akcan A, Akyıldız H, Deneme MA, Akgun H, Arıtas Y. Granulomatous lobular mastitis: a complex diagnostic and therapeutic problem. World J Surg. 2006 Aug 1;30(8):1403-9.

Asoglu O, Ozmen V, Karanlik H, Tunaci M, Cabioglu N, Igci A, et al. Feasibility of surgical management in patients with granulomatous mastitis. Breast J. 2005 Mar;11(2):108-14.

Veyssiere C, Vives M, Smadja A. Difficultés diagnostiques de la tuberculose mammaire. Le problème de la mastite granulomateuse. Lille Chir. 1967;22:104-9.

Akcan A, Akyıldız H, Deneme MA, Akgun H, Arıtas Y. Granulomatous lobular mastitis: a complex diagnostic and therapeutic problem. World J Surg. 2006 Aug 1;30(8):1403-9.

Taylor GB, Paviour SD, Musaad S, Jones WO, Holland DJ. A clinicopathological review of 34 cases of inflammatory breast disease showing an association between corynebacteria infection and granulomatous mastitis. Pathol. 2003 Jan 1;35(2):109-19.

Diesing D, Axt-Fliedner R, Hornung D, Weiss JM, Diedrich K, Friedrich M. Granulomatous mastitis. Arch Gynecol Obstet. 2004;269(4):233-6.

Brown KL, Tang PH. Postlactational tumoral granulomatous mastitis: a localized immune phenomenon. Am J Surg. 1979 Aug 1;138(2):326-9.

Katz U, Molad Y, Ablin J, Ben-David D, Paran D, Gutman M, et al. Chronic idiopathic granulomatous mastitis. Ann N Y Acad Sci. 2007;1108:603-8.

Anik Y. Radiological findings of idiopathic granulomatous mastitis. Turkiye Klinikleri J Med Sci. 2010;30(1):286-92.

Dursun M, Yilmaz S, Salmaslioglu A, Yavuz E, Igci A, Acunas G, et al. Multimodality imaging features of idiopathic granulomatous mastitis: Outcome of 12 years of experience. Radiol Med. 2012;117:529-38.

Baslaim MM, Khayat HA, Al-Amoudi SA. Idiopathic granulomatous mastitis: a heterogeneous disease with variable clinical presentation. World J Surg. 2007 Aug 1;31(8):1677-81.

Al-Khaffaf B, Knox F, Bundred NJ. Idiopathic granulomatous mastitis: a 25-year experience. J Am Coll Surg. 2008 Feb 1;206(2):269-73.

Wilson JP, Massoll N, Marshall J, Foss RM, Copeland EM, Grobmyer SR. Idiopathic granulomatous mastitis: In search of a therapeutic paradigm. Am Surg. 2007;73:798-02.

DeHertogh DA, Rossof AH, Harris AA, Economou SG. Prednisone management of granulomatous mastitis. N Engl J Med. 1980 Oct 2;303(14):799-800.