Published: 2019-12-25

Clinical profile and management of pyogenic liver abscesses in a tertiary care hospital

Shyam K. Gupta, Ashufta Rasool, Aamir H. Hela, Rohit Goel, Zahur Hussain


Background: Pyogenic Liver abscesses are potentially life threatening if left untreated. They pose a major Diagnostic and therapeutic challenge to modern world. Interventional radiology is becoming standard of care for liver Abscesses.

Methods: All patients of pyogenic liver abscess admitted to Government Medical College and hospital Jammu, J and K, India from October 2018 to November 2019 were prospectively studied. Demographics, presentation, lab reports and management strategies were evaluated.

Results: Total of 60 patients of pyogenic liver abscesses were studied with 81.7% males. Alcohol was found to be most common risk factor with 55% of patients being alcoholic. Right lobe of liver was involved in 66.7% of patients. Segment VI and VII were involved in 50% of patients. The most common clinical symptom was right upper quadrant pain (98.3%), followed by fever (91.7%). The most common clinical sign was right upper quadrant tenderness (91.7%). Percutaneous drainage with catheter placement was the most common and successful modality of management associated with least hospital stay.

Conclusions: Pyogenic liver abscess is a rare but serious problem. Early diagnosis and treatment are necessary to avoid mortality. Percutaneous drainage along with I.V antibiotics is the best form of management.


Hepatic abscess, Liver abscess, Management of liver abscess, Pyogenic liver abscess, Percutaneous drainage of liver abscesses

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Barnes PF, DeCock KM, Reynolds TN, Ralls PW. A comparison of pyogenic and amoebic abscess of liver. Medicine. 1987;66(6):472-83.

O'Farrell N, Collins CG, McEntee GP. Pyogenic liver abscesses: diminished role for operative treatment. Surgeon. 2010 Aug 1;8(4):192-6.

Mezhir JJ, Fong Y, Jacks LM, Getrajdman GI, Brody LA, Covey AM, et al. Current management of pyogenic liver abscess: surgery is now second-line treatment. J Am Coll Surg. 2010 Jun 1;210(6):975-83.

Seeto RK, Rockey DC. Pyogenic liver abscess. Changes in etiology, management, and outcome. Medicine. 1996 Mar;75(2):99-113.

Chou FF, Sheen-Chen SM, Chen YS, Chen MC. Single and multiple pyogenic liver abscesses: clinical course, etiology, and results of treatment. World J Surg. 1997 May 1;21(4):384-9.

Chu KM, Fan ST, Lai EC, Lo CM, Wong J. Pyogenic liver abscess: an audit of experience over the past decade. Archiv Surg. 1996 Feb 1;131(2):148-52.

Huang CJ, Pitt HA, Lipsett PA, Osterman Jr FA, Lillemoe KD, Cameron JL, et al. Pyogenic hepatic abscess. Changing trends over 42 years. Annal Surg. 1996 May;223(5):600.

Bugti QA, Baloch MA, ul Wadood A, Mulghani AH, Azeem B, Ahmed J. Pyogenic liver abscess: demographic, clinical, radiological and bacteriological characteristics and management strategies. Gomal J Med Sci. 2005;3(1).

Liew KV, Lau TC, Ho CH, Cheng TK, Ong YS, Chia SC, et al. Pyogenic liver abscess-a tropical centre's experience in management with review of current literature. Singapore Med J. 2000 Oct;41(10):489-92.

Gyorffy EJ, Frey CF, Silva Jr JO, Mcgahan JO. Pyogenic liver abscess. Diagnostic and therapeutic strategies. Annals of surgery. 1987 Dec;206(6):699.

Sharma MP, Kumar A. Liver abscess in children. Ind J Pediatr. 2006;73(9):813-7.

Kebede A, Kassa E, Ashenafi S, Woldemichael T, Polderman AM, Petros B. Amoebic liver abscess: A 20-year retrospective analysis at Tikur Anbessa Hospital, Ethiopia. Ethiop J Health Develop. 2004;18(3):199-202.