Levels of serum lithium in manic depressive patients with mild persistent bronchial asthma

Subhramay Chatterjee; Sandip Chakraborti

doi:10.18203/2320-6012.ijrms20200776

Authors

Subhramay Chatterjee Department of Biochemistry, Murshidabad Medical College and Hospital, Berhampore, West Bengal, India
Sandip Chakraborti Department of Biochemistry, NRS Medical College and Hospital, Kolkata, West Bengal, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20200776

Keywords:

Bronchial asthma, Lithium, Manic depressive

Abstract

Background: Lithium, widely used in manic depressive (MD) patients, might protect the airways against constrictor stimuli in bronchial asthma (BA), through its effects on cell signal transduction and ion transport pathways.

Methods: Serum lithium levels were studied in MD patients with better controlled mild persistent BA (group A) and MD patients with not so well controlled BA (group B).

Results: Serum lithium levels were highly significantly more in group A compared to lithium levels in group B.

Conclusions: Lithium may inhibit the contractile response of airway smooth muscle and can be used in treatment / monitoring of BA.

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