Pattern of breast lesions on fine-needle aspiration cytology in consecutive 70 cases: a retrospective and prospective analysis of one year

Roma Singh, Nipun Saproo


Background: Breast lumps constitute a significant proportion of surgical cases in both developed and developing countries. In outpatient department breast lump is one of the commonest presentations, majority of them are in women and are benign. It is needed to distinguish benign lumps from malignant preoperatively for definite treatment.

Methods: The present study is a retrospective and prospective study of one year and spans duration from 1st January 2015 to 31st December 2015, a total 70 cases were studied which included 67 female patients and 03 male patient. This study is been conducted in the department of pathology, L.N medical college and Associated J.K Hospital and research centre Bhopal (Madhya Pradesh). Cytomorphological features of breast lesions were studied and correlated with clinical and histological features.

Results: The present study was conducted on 70 patients with palpable breast lump. Fibroadenoma was the most common benign breast lesion encountered and lump was the most common symptom.

Conclusion: Most of the breast lesions are benign and needs only reassurance. The FNAC gives result very fast and is accurate therefore FNAC is useful in those cases, to avoid fear of surgery, benign breast lesions commonly affect the younger age group. Fibroadenoma is the most common lesion encountered in benign breast lesions.



Breast lump, Benign, FNAC, Cytomorphological

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Vaidyanathan L, Barnard K, Elnicki DM. Benign breast disease: When to treat, when to reassure, when to refer. Cleve Clin J Med. 2002;69:425-32.

Guray M, Sahin AA. Benign breast diseases: Classification, diagnosis, and management. Oncologist. 2006;11:435–49.

Chaiwun B, Settakorn J, Ya-In C, Wisedmongkol W, Rangdaeng S, Thorner P. Effectiveness of fine-needle aspiration cytology of breast: Analysis of 2375 cases from northern Thailand. Diagn Cytopathol. 2002;26:201-5.

Nguansangiam S, Jesdapatarakul S, Tangjitgamol S. Accuracy of fine needle aspiration cytology from breast masses in Thailand. Asian Pac J Cancer Prev. 2009;10:623-6.

Cobb CJ, Raza AS. Obituary: “Alas poor FNA of breast — We knew thee well!” Diagn Cytopathol. 2005;32:1-4.

Orell SR, Miliauskas J. Fine needle biopsy cytology of breast lesion: A review of interpretative difficulties. Adv Anat Pathol. 2005;12:233-45.

Zagorianakou P, Fiaccavento S, Zagorianakou N, Makrydimas G, Stefanou D, Agnatis NJ. FNAC: Its role, limitations and perspective in the preoperative diagnosis of breast cancer. Eur J Gynaecol Oncol. 2005;26:143-9.

Muddegowda PH, Lingegowda JB, Krupad R, Konapur PG, Shivarudrappa A, Subramaniam P. The value of systematic pattern analysis in FNAC of breast lesions: 225 cases with cytohistological correlation. J Cytol. 2011;28:13-9.

Joshi A, Maimoon S. Limitations of fine needle aspiration cytology in subtyping breast malignancies- A report of three cases. J Cytol. 2007;24:203-6.

Kaufman Z, Shpitz B, Shapiro M, Runa R, Lew S, Dinbar A. Tripple approach in the diagnosis of dominant breast masses: Combined physical examination, mammography and fine needle aspiration. J Surg Oncol. 1994;56:254-7.

Rosa M, Mohammadi A, Masood S. The value of fine needle aspiration biopsy in the diagnosis and prognostic assessment of palpable breast lesion. Diagn Cytopathol.2012;40:26-34.

Chandanwale SS, Buch AC, Gore CR, Ramanpreet KC, Jadhav P. Fine needle aspiration cytology in breast tuberculosis: Diagnostic difficulties- study of eleven cases.Indian J Tuberc. 2012;59:162-7.

Ariga R, Bloom K, Reddy VB, Kluskens L, Francescatti D, Dowlat K, et al. Fine needle aspiration of clinically suspicious palpable breast masses with histopathologic correlation. Am J Surg. 2002;184:410-3.

Farkhanda JD, Muhammad SA, Ahsan AL, Noor MK, Imtiaz S, Zulfiqar IM. An early diagnosis of benign breast diseases. Journal of Surgery, Pakistan. 2010;15(4):74-8.

Haque, Tyagi, Khan, Gahlut. Breast lesions: a clinicohistopathological study of 200 cases of breast lump. JAMA. 1980;150:1810-4.