Open radical nephrectomy for early treatment of renal cell carcinoma: a case report and review

Juan José Granados-Romero; Alan Isaac Valderrama-Treviño; Germán-Eduardo Mendoza-Barrera; Jesús Carlos Ceballos-Villalva; Ericka Hazzel Contreras-Flores; Baltazar Barrera-Mera; Mariana Espejel-Deloiza; Aranza Guadalupe Estrada-Mata; Kassandra Denisse Badillo-Martínez; Ángeles Rodal-Soler

doi:10.18203/2320-6012.ijrms20161265

Authors

Juan José Granados-Romero Department of Surgery, Hospital General de México
Alan Isaac Valderrama-Treviño PhD student in biomedical sciences, Faculty of Medicine, UNAM
Germán-Eduardo Mendoza-Barrera Department of Surgery, Faculty of Medicine, UNAM
Jesús Carlos Ceballos-Villalva Undergraduate student, AFINES, Faculty of Medicine, UNAM
Ericka Hazzel Contreras-Flores Undergraduate student, AFINES, Faculty of Medicine, UNAM
Baltazar Barrera-Mera Department of physiology, Faculty of Medicine, UNAM
Mariana Espejel-Deloiza Undergraduate student, AFINES, Faculty of Medicine, UNAM
Aranza Guadalupe Estrada-Mata Undergraduate student, AFINES, Faculty of Medicine, UNAM
Kassandra Denisse Badillo-Martínez Undergraduate student, AFINES, Faculty of Medicine, UNAM
Ángeles Rodal-Soler Undergraduate student, AFINES, Faculty of Medicine, UNAM

DOI:

https://doi.org/10.18203/2320-6012.ijrms20161265

Keywords:

Renal tumor, Surgical treatment, Radical nephrectomy

Abstract

We report the case of a 46-year-old male with no previous medical background. He complained of abdominal right-sided flank pain, spreading to ipsilateral flank, thermal hikes, hematuria, and positive giordano. The ultrasound found a 5 x 5 cm mass located in right kidney upper pole, which did not compromised renal capsule and presented a fresh bruise, suggesting a malignant tumor. Radical nephrectomy was satisfactory performed; sending the whole kidney to pathology and the patient was discharged within 72 hours. The histopathologic report concluded a conventional clear cell renal cell carcinoma tumor (5.5 x 4.8 cm) Fuhrman grade II, limited to the renal parenchyma. We concluded that the best treatment for this type of cancer is the radical nephrectomy even though you lose a part of the renal function. Radical nephrectomy guarantees the extraction of the whole tumor and avoids dissemination, one of the most common complications.

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References

Amin M, Tamboli P, Javidan J, Stricker H, Peralta M, Deshpande A, et al. Prognostic impact of histologic subtyping of adult renal epithelial neoplasm: an experience of 405 cases. Am J Surg Pathol. 2002;26:281-91.

Rouprêt M, Zigeuner R, Palou J, Boehle A, Kassinen E, Sylvester R, et al. European guidelines for the diagnosis and management of upper urinary tract urothelial cell carcinomas: 2011 update. Eur Urol. 2011;59:584.

Yu M, Mack T, Hanisch R. Cigarette smoking, obesity, diuretic use, and coffee consumption as risk factors for renal cell cancer study. Int J Cancer. 1995;60:194-8.

Bhatt J, Finelli A. Landmarks in the diagnosis and treatment of renal cell carcinoma. Nature Review Urology. 2014;11:517-25.

Kwon S, Song C. Risk of chronic kidney disease after nephrectomy for renal cell carcinoma. Korean J Urol. 2014;55:636-42.

Clague J, Lin J, Cassidy A, Matin S, Tannir N, Tamboli P, et al. Family history and risk of renal cell carcinoma: results from a case-control study and systematic meta-analysis. Cancer Epidemiol Biomarkers Prev. 2009;18(3):801-7.

Navarro M, Rodríguez C. Carcinoma de células renales: caracterísiticas morfológicas y hallazgos clínicopatológicos en 76 casos. Rev Sanid Milit Mex. 2007;61(5);320-8.

Ferlay J, Autier P, Boniol M, Heanue M, Colombet M, Boyle P. Estimates of the cancer incidence and mortality in Europe in 2006. Ann Oncol. 2007;18(3):581-92.

Levi F, Ferlay J, Galeone C, Lucchini F, Negri E, Boyle P, La Vecchia C. The changing pattern of kidney cancer incidence and mortality in Europe. BJU Int. 2008;101(8):949-58.

Morrison P, Donnelly D, Atkinson A, Maxwell A. Advances in the Genetics Of Familial Renal Cancer. The oncologist. 2010;15:532-8.

Maher E, Yates J, Harries R, Benjamin C, Harris R, Moore A, et al. Clinical features and natural story of von Hippel-Lindau disease. Q J Med. 1990;77: 1151-63.

Ries L, Melbert D, Krapcho M, Stinchcomb D, Howlader N, Horner M, et al. SEER Cancer Statistics Review, 1975-2005, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/ csr/1975_ 2005/, based on November 2007 SEER data submission, posted to the SEER web site, 2008.

Dirección General de Epidemiología. Registro Histopatológico de Neoplasias Malignas en Secretaría de Salud. México. 2003.

Walsh P, Kavoussi L, Novick A. Renal tumors. J Urol. 2002;75:2672-721.

Alpers C. El riñón. En: Kumar V, Abbas A, Fausto N, Aster J. Robbins & Cotran. Patología estructural y funcional. 8va ed. España:Elsevier; 2010. p. 905-969.

Gudas L, Fu L, Minton D, Mongan N, Nanus D. The Role of HIF1α in Renal Cell Carcinoma Tumorigenesis. J Mol Med(Berl). 2014;92(8):825-36.

Lipworth L, Tarone R, McLaughin J. The epidemiology of renal cell carcinoma. J Urol. 2006;176(6):2353-8.

Zhu Y, Horikawa Y, Yang H, Wood C, Habuchi T, Wu X. BPDE Induced Lymphocytic Chromosome 3p Deletions May Predict Renal Cell Carcinoma Risk. J Urol. 2008;179(6):2416-21.

Hamdy F, Baster J, Neal D. Management of urologic malignancies. J Urol. 2002;19:273-5.

Fekak H, Bennani S, Taha A, Rabii R, Joual A, Sarf S, et al. Kidney cancer: report of 170 cases. Ann D Urologie. 2001;35(5):249-56.

Chandler J, Heaney W. Metastatic renal cell carcinoma presenting as a skin nodule: case report and review of the literature. J Urol. 1994;152:2094-5.

Koroupakis D, Atsea E, Sofras F, Apostolikas N. Renal cell carcinoma metastases to the skin : a not so rare case? Br J Urol. 1995;75(5):583-5.

Shigheiko K, Sathoshi T, Masaharu N. Renal cell carcinoma metastatic to the skin. Anticancer Researh. 20: 1939- 2000.

Asimakopoulos A, Miano R, Annino F, Micali S, Spera E, Iorio B, et al. Robotic radical nephrectomy for renal cell carcinoma: a systematic review. BMC Urology. 2014;14(75):1-6.

Adam A, Kenny L. Interventional oncology in multidiscilinary cancer treatment in the 21st century. Nature Rev Clin Oncol. 2015;12:105-13.

Acar C, Bilen C, Bayazit Y, Aslan G, Koni A, Basok E, et al. Quality of Life Survey Following Laparoscopic and Open Radical Nephrectomy. Laparoscopic Urology. 2014;11(6):1944-50.

Etafy M, Saleh F, Abdel M, Gawish M, Morsy G. Comparasion of Renal Function Following Donor Nephrectomy Versus Radical Nephrectomy for Renal Tumor. Saudi J Kidney Dis Transpl. 2015;26(2):238-42.

Li L, Ling W, Rhee C, Harley K, Kovesdy C, Sim J, et al. Risk of chronic kidney disease after cancer nephrectomy. Nature Reviews Nephrology. 2014;10(3):135-45.

Wu Z, Li M, Liu B, Cai C, Ye H, Lv C, et al. Robotic versus Open Partial Nephrectomy: A Systematic Review and Meta-Analisis. PloS ONE. 2014;9(4):1-8.

Kim C, Bae E, Ma S, Kweon S, Kim S. Impact of partial nephrectomy on kidney function in patient’s whit renal cell carcinoma. BMC Nephrology. 2014;15:1-8.

Robson C. Radical nephrectomy for renal cell carcinoma. J Urol. 1963;89:37-42.

Scott W, Wein A, Kavoussi L, Partin A, Peters A. Campbell-Walsh Urology.10.ª ed. Philadelphia: ELSEVIER; 2012; pp. 1449-1452.

Hohenfellner R, Castiñeiras J, Gillitzer R, Fichtner J. Innovaciones en cirugía urológica. Barcelona: Caronte; 2000; pp. 155-74.

Russo P. Deleterious renal functional outcomes after radical nephrectomy. Eur Urol. 2011;59:340-1.

Badalato G, Kates M, Wisnivesky J, Choudhury A, McKiernan J. Survival After Partial and Radical Nephrectomy for the Treatment of Stage T1bN0M0 Renal Cell Carcinoma (RCC) in the USA: A Propensity Scoring Approach. BJU Int. 2012;109(10):1457-62.