Calcifying fibrous tumour: a rare case report of an exceptional lesion localized in retroperitoneum, mesentery and pelvis
DOI:
https://doi.org/10.18203/2320-6012.ijrms20201953Keywords:
Benign mesenchymal lesion, Calcifying fibrous tumour, Calcification, Immunohistochemistry, RetroperitoneumAbstract
Calcifying fibrous tumours are rare benign lesions affecting mostly children and young adults. A 17-year-old female presented with abdominal pain and abdominal distention. Physical examination revealed intra-abdominal mass occupying retro peritoneum and right iliac fossa. Excisional biopsy from peritoneum and mesentery were performed. Histopathologically, it was composed of hypocellular hyalinised collagenized stroma, spindle cells, psammomatous and dystrophic calcification and mononuclear inflammatory cell infiltration. Authors are here in reporting a case of calcifying fibrous tumour and discussing its clinical and morphological features with regard to the literature.
References
Rosenthal NS, Abdul-Karim FW. Childhood fibrous tumor with psammoma bodies. Clinicopathologic features in two cases. Arch Pathol Lab Medi. 1988 Aug;112(8):798-800.
Fetsch JF, Montgomery EA, Meis JM. Calcifying fibrous pseudotumor. Am J Surg Pathol. 1993 May;17(5):502-8.
Nascimento AF, Ruiz R, Hornick JL, Fletcher CD. Calcifying Fibrous ‘Pseudotumor’ Clinicopathologic Study of 15 Cases and Analysis of its Relationship to Inflammatory Myofibroblastic Tumor. Int J Surg Pathol. 2002 Jul;10(3):189-96.
Chorti A, Papavramidis TS, Michalopoulos A. Calcifying fibrous tumor: review of 157 patients reported in international literature. Medicine. 2016 May;95(20):1-12.
Weiss SW, Goldblum JR, Folpe AL. Enzinger and Weiss's soft tissue tumors. In: Weiss SW, Goldblum Jr, eds. 6th ed. Elsevier Health Sciences; 2007 Nov 29: 294-297.
Jaiswal SS, Agrawal A, Sahai K, Nair SK. Large retroperitoneal calcifying fibrous tumor. Medi J, Armed Forces Ind. 2013 Apr;69(2):184.
Gamsızkan M, Yıldırım C, Daş K, Günhan Ö. Calcifying fibrous tumor: A case report/kalsifiye fibröz tümör: Olgu sunumu. Turkish J Pathol. 2015 May 1;31(2):141-4.
El O, El A, Belghith M, Goucha A, Gabsi A, Gamoudi A. Cancer Science & Therapy Calcifying Fibrous Tumour : Report of an Exceptional Lesion Localized to the Jejunum. J Cancer Sci Ther. 2016;8(12):283-5.
Fukunaga M, Kikuchi Y, Endo Y, Ushigome S. Calcifying fibrous pseudotumour. Pathol Int. 1997;47:60-63.
