DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20202277

Impact of transition in socio-economic status on sonographically detected non-alcoholic fatty liver disease: a study based on modified Kuppuswamy classification in an urban population

Abhinav Jain, Smita Manjavkar, Humaid Ali Jafri, S. S. Anand

Abstract


Background: The transition in the socioeconomic status is associated with physical and mental challenges. The lifestyle modification is one of the key implicatory for this change. Non-alcoholic fatty liver is an ever-growing health concern. This study evaluates the socioeconomic categories based on Kuppuswamy classification and other correlated in sonographically detected Non-alcoholic fatty liver disease (NAFLD).

Methods: This cross-sectional study was conducted on 300 sonographically detected NAFLD patients in the age group of 18-60 years. Detailed history, including the demographic profile, socio-economic status (Modified Kuppuswamy scale was followed for calculating the Socio-economic status of the family), occupation, dietary habits (vegetarian or non-vegetarian, exposure to junk food), drinking water supply, etc. Detailed assessment of the morphological parameters including the anthropometric measurements, height, BMI was also assessed.

Results: The study finds 62 (41%) females and 88 (59%) males with NAFLD and 51-60 age group with maximum prevalence. Diabetes (63%), Soft drink consumption and obesity are important risk factors. New observation of our study is that amongst various Kuppuswami sociodemographic scales, the maximum patients belonging to Upper middle class and upper lower class presented with fatty liver.

Conclusions: There is higher prevalence of NAFLD amongst males, diabetics, obese, soft drinks, tea and coffee consumers. Authors also find a unique correlate based on socio-demographic class of Kuppuswami scale. People belonging to upper middle class and upper lower class suffer from NAFLD more commonly than other sociodemographic classes.


Keywords


Fatty liver, Non-alcoholic fatty liver disease, Sociodemographic, Ultrasonography

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References


Bellentani S, Marino M. Epidemiology and natural history of non-alcoholic fatty liver disease (NAFLD). Ann Hepatol. 2009;8(Suppl 1):S4-8.

Dabhi AS, Brahmbhatt KJ, Pandya TP, Thorat PB, Shah MC. Non-alcoholic fatty liver disease (NAFLD). J Ind Acad Clin Med. 2008;9:36-41.

Clark JM, Brancati FL, Diehl AM. The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastroenterol. 2003;98:960-7.

Bellentani S, Saccoccio G, Masutti F, Crocè LS, Brandi G, Sasso F, et al. Prevalence of and risk factors for hepatic steatosis in Northern Italy. Ann Intern Med. 2000;132(2):112-7.

Majumdar A, Misra P, Sharma S, Kant S, Krishnan A, Pandav CS. Prevalence of nonalcoholic fatty liver disease in an adult population in a rural community of Haryana, India. Indian J Public Health 2016;60:26-33.

Mohan V, Farooq S, Deepa M, Ravikumar R, Pitchumoni CS. Prevalence of non-alcoholic fatty liver disease in urban South Indians in relation to different grades of glucose intolerance and metabolic syndrome. Diabetes Res Clin Pract. 2009;84:84-91.

El-Koofy NM, Anwar GM, El-Raziky MS, El-Hennawy AM, El-Mougy FM, El-Karaksy HM, et al. The association of metabolic syndrome, insulin resistance and non-alcoholic fatty liver disease in overweight/obese children. Saudi J Gastroenterol. 2012;18(1):44.

Marchesini G, Bugianesi E, Forlani G, Cerrelli F, Lenzi M, Manini R, et al. Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatol. 2003;37(4):917-23.

Singh SP, Nayak S, Swain M. Prevalence of nonalcoholic fatty liver disease in coastal eastern India: a preliminary ultrasonographic survey. Trop Gastroenterol. 2004;25:76-9.

Williamson RM, Price JF, Glancy S, Perry E, Nee LD, Hayes PC, et al. On behalf of the edinburgh type 2 diabetes study investigators. prevalence of and risk factors for hepatic steatosis and nonalcoholic fatty liver disease in people with type 2 diabetes: the edinburgh type 2 diabetes study. Diabetes Care. 2011;34:1139-44.

Angulo P, Keach JC, Batts KP, Lindor KD, Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis. Hepatol. 1999;30:1356-62.

Younossi ZM, Gramlich T, Matteoni CA, et al., Nonalcoholic fatty liver disease in patients with type 2 diabetes. Clin Gastroenterol Hepatol 2004;2:262-5.

Kalra S, Vithalani M, Gulati G, Kulkarni CM, Kadam Y, Pallivathukkal J, et al. Study of prevalence of nonalcoholic fatty liver disease (NAFLD) in type 2 diabetes patients in India (SPRINT). J Assoc Physicians India. 2013;61(7):448-53.

Zelber-Sagi S, Nitzan-Kaluski D, Goldsmith R, Webb M, Blendis L, Halpern Z, et al. Long-term nutritional intake and the risk for non-alcoholic fatty liver disease (NAFLD): a population-based study. J Hepatol. 2007;47(5):711-7.

Assy N, Nasser G, Kamayse I, Nseir W, Beniashvili Z, Djibre A, et al. Soft drink consumption linked with fatty liver in the absence of traditional risk factors. Canad J Gastroenterol Hepatol. 2008;22(10):811-6.

Choudhary NS, Duseja A, Kalra N, Das A, Dhiman RK, Chawla YK. Correlation of adipose tissue with liver histology in Asian Indian patients with nonalcoholic fatty liver disease (NAFLD). Ann Hepatol. 2012;11(4):478-86.

Patell R, Dosi R, Joshi H, Sheth S, Shah P, Jasdanwala S. Non-alcoholic fatty liver disease (NAFLD) in obesity. J Clin Diagnos Res. 2014;8(1):62.

Marventano S, Salomone F, Godos J, Pluchinotta F, Del Rio D, Mistretta A, et al. Coffee and tea consumption in relation with non-alcoholic fatty liver and metabolic syndrome: a systematic review and meta-analysis of observational studies. Clin Nutr. 2016;35(6):1269.