Anticoagulation in pulmonary TB induced deep vein thrombosis is it always warranted: a case report

Authors

  • Binal Nitin Lodaria Department of Pediatrics, SBKS MIRC, Waghodia, Vadodara, Gujarat, India
  • Prasad Muley Department of Pediatrics, SBKS MIRC, Waghodia, Vadodara, Gujarat, India
  • Dhrumika Sheth Department of Pediatrics, SBKS MIRC, Waghodia, Vadodara, Gujarat, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20202916

Keywords:

ATT, Anti-coagulation, Deep vein thrombosis, Pulmonary tuberculosis

Abstract

India is a densely populated developing country and accounts for one quarter of the total tuberculosis cases reported worldwide. Deep vein thrombosis (DVT) has been associated with 1.5-3.4% cases of tuberculosis. A 14 year female presented with complaints of cough with progressive breathlessness (NYHA Grade III) since 15 days along with easy fatiguability and fever for 3 days. The patient was started on Anti-Tubercular Treatment (ATT) as per RNTCP guidelines after thorough investigations. One week after the patient was started on ATT, the patient developed edema of the right lower limb accompanied by pain. Color doppler was suggestive of thrombosis in the superficial and deep veins. Early immobilization and physiotherapy was started immediately. Over a period of 10 days, the swelling gradually decreased, and pain subsided. Tuberculosis is an independent risk factor for the development of venous thromboembolism irrespective of the presence of other risk factors. Emphasis is thus laid on high index of suspicion and early diagnosis to control and prevent further complications like pulmonary embolism. We can propose that in patients diagnosed with pulmonary tuberculosis, early immobilization and physiotherapy can prevent the development of DVT.

References

World Health Organization. Report on the Tuberculosis Epidemic. Geneva: World Health Organization; 2014

White NW. Venous thrombosis and rifampicin. Lancet. 1989;2:434-5.

Gupta A, Mrigpuri P, Faye A, Bandyopadhyay D, Singla R. Pulmonary tuberculosis - An emerging risk factor for venous thromboembolism: A case series and review of literature. Lung India. 2017;34(1):65-9.

Robson SC, White NW, Aronson I, Woolgar R, Goodman H, Jacobs P. Acute-phase response and the hypercoagulable state in pulmonary tuberculosis. Br J Haematol. 1996;93:943-9.

Suárez Ortega S, Artiles Vizcaíno J, Balda Aguirre I, Melado Sánchez P, Arkuch Saade ME, Ayala Galán E, et al. Tuberculosis as risk factor for venous thrombosis. An Med Interna. 1993;10:398-400.

Ambrosetti M, Ferrarese M, Codecasa LR, Besozzi G, Sarassi A, Viggiani P, et al. Incidence of venous thromboembolism in tuberculosis patients. Respiration. 2006 May 1;73(3):396.

Kechaou I, Cherif E, Ben Hassine L, Khalfallah N. Deep vein thrombosis and tuberculosis: a causative link? BMJ Case Rep. 2014;2014.

Kouismi H, Laine M, Bourkadi JE, Iraqi G. Association of deep venous thrombosis with pulmonary tuberculosis. Egyptian J Chest Dis Tuberculosis. 2013 Jul 1;62(3):541-3.

Muley P, Shah U, Shah V, Gandhi D. Deep vein thrombosis with tuberculosis: A rate presentation of common disease. Global J Med Public Health. 2014;3:1-4.

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Published

2020-06-26

How to Cite

Lodaria, B. N., Muley, P., & Sheth, D. (2020). Anticoagulation in pulmonary TB induced deep vein thrombosis is it always warranted: a case report. International Journal of Research in Medical Sciences, 8(7), 2678–2680. https://doi.org/10.18203/2320-6012.ijrms20202916

Issue

Section

Case Reports