Quality of life of carpal tunnel syndrome with non operative treatment: cohort study


  • Merlin P. Kastilong Department of Neurology, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia
  • Karema Winifred Department of Neurology, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia
  • Sekplin A. S. Sekeon Department of Neurology, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia




Carpal tunnel syndrome, Non operative treatment, Quality of life


Background: Carpal tunnel syndrome (CTS) is the most common peripheral neuropathy entrapment and it interferes with the quality of life. Treatment for CTS can be divided into operative and non-operative treatment. Our objective was to compare the quality of life and pain intensity in a patient with CTS after oral treatment and local corticosteroid injection (LCI).

Methods: A prospective cohort study was conducted in 18-65 years patients with CTS. Primary outcome was to compare the quality of life post oral treatment (NSAIDs, oral steroids, gabapentin) and LCI using the Short Form-36 questionnaire. Secondary output was to compare pain intensity using Numeric Rating Scale (NRS). Mann-Whitney and independent t-test were used to assess the comparison between the treatment.

Results: Sixty CTS patients were included in this study, with 32 patients (53.33%) assigned to LCI. After observation one month, statistical analysis showed that LCI improved the quality of life better than oral in physical function and bodily pain components (p = 0.036 and p = 0.047). Injection treatment decreased pain intensity more than oral not statistically significant after 14 days (p=0.087), but was significant after one month (p=0.002).

Conclusions: Local corticosteroid injection improved quality of life and decreased pain intensity better than oral treatment after one month.


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How to Cite

Kastilong, M. P., Winifred, K., & Sekeon, S. A. S. (2020). Quality of life of carpal tunnel syndrome with non operative treatment: cohort study. International Journal of Research in Medical Sciences, 8(7), 2502–2508. https://doi.org/10.18203/2320-6012.ijrms20202886



Original Research Articles