Serum iron level in patients with COVID-19: a case report study


  • Rasoul Alipour Department of Emergency Medicine, Emergency Unit of Alinasab Hospital, Social Security Organisation, Treatment Management of East Azerbaijan, Tabriz, Iran
  • Seyed Hasan Hashemi Department of Gastroenterology, Gastroenterology unit of Alinasab Hospital, Social Security Organisation, Treatment Management of East Azerbaijan, Tabriz, Iran
  • Fariba Mikaeili Department of Midwifery, Islamic Azad University, Tabriz, Iran



Coronavirus, COVID-19, Ferritin, Hepcidin, Serum iron level


Coronavirus disease emerged in Wuhan, China in December 2019 and led to worldwide pandemic in March 2020. Due to early diagnose, treatment and prevent transmission of COVID-19 disease, we need rapid laboratory tests and develop them. This paper focuses on serum Iron level in patients with COVID-19. We assess the serum Iron level due to the following reasons: I. Iron is a key part of hemoglobin structure in which is essential for providing Oxygen to the body organs, particularly for the patients with pulmonary involvement such as COVID-19. II. Iron deficiency can contribute to muscle weakness and reduction of respiratory capacity, at which increases the risk of deterioration of COVID-19 patients. III. Elevation in Hepcidin level (due to the increase in IL-6 level) in COVID-19 patients inhibits Iron absorption from intestinal lumen and blocks the Iron release from macrophages. IV. Iron is an essential element in infectious suppress and inflammatory process. We noticed that most of the patients, especially admitted to hospital due to the respiratory symptoms, have lower serum Iron level.


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How to Cite

Alipour, R., Hashemi, S. H., & Mikaeili, F. (2020). Serum iron level in patients with COVID-19: a case report study. International Journal of Research in Medical Sciences, 8(7), 2658–2662.



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