Utility of urine reagent strips in rapid bedside diagnosis of bacterial meningitis

Authors

  • Nanda Patil Department of Pathology, Krishna Institute of Medical Sciences Deemed to be University, Karad, Maharashtra, India
  • Sujata Kanetkar Department of Pathology, Krishna Institute of Medical Sciences Deemed to be University, Karad, Maharashtra, India
  • Garima Agarwal Department of Pathology, Krishna Institute of Medical Sciences Deemed to be University, Karad, Maharashtra, India
  • Supriya Karmakar Department of Pathology, Krishna Institute of Medical Sciences Deemed to be University, Karad, Maharashtra, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20203443

Keywords:

Bacterial meningitis, CSF analysis, Reagent strips

Abstract

Background: Bacterial meningitis is a medical emergency and late diagnosis and treatment can lead to neurological damage and death. For definitive diagnosis of meningitis, laboratory based CSF analysis is required which is based on microscopy, protein and sugar estimation. This requires laboratory set up with experienced pathologist and long turn around time. Hence urinary reagent strips as a semiquantitative method can be applied for CSF analysis. This method can be used where laboratory set up is not available as well as bedside test for early diagnosis of bacterial meningitis. The present prospective study was undertaken to evaluate the utility of urine reagent strips in rapid diagnosis of bacterial meningitis. The aim of the present was to evaluate the role of urine reagent strips in the analysis of cerebrospinal fluid in suspected cases of meningitis.

Methods: The prospective study was carried out in the department of pathology in a tertiary care centre for a period of 6 months from September 2018 to February 2019. CSF analysis of suspected cases of meningitis was done with urine reagent strip as well as with standard laboratory method. The results of both were compared.

Results: Out of 79 cases of meningitis, 68.35% cases were of bacterial meningitis. The specificity and sensitivity of CSF analysis with reagent strip was 93.33% and 82.35% respectively, for cell count, 94.4% and 88.2% respectively for proteins and 91.3% and 60.2% respectively for glucose.

Conclusions: Semiquantitative analysis of CSF sample with urine reagent strips helps in rapid diagnosis of bacterial meningitis and can be useful to facilitate therapeutic decisions in resource constrained settings.

References

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Published

2020-07-24

How to Cite

Patil, N., Kanetkar, S., Agarwal, G., & Karmakar, S. (2020). Utility of urine reagent strips in rapid bedside diagnosis of bacterial meningitis. International Journal of Research in Medical Sciences, 8(8), 2947–2949. https://doi.org/10.18203/2320-6012.ijrms20203443

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Section

Original Research Articles