A clinical study of arrhythmias associated with acute coronary syndrome: a hospital based study of a high risk and previously undocumented population
DOI:
https://doi.org/10.18203/2320-6012.ijrms20203457Keywords:
Acute coronary syndrome, Cardiac arrhythmia, Non- ST elevated ACS, ST elevated ACSAbstract
Background: ACS represents a global epidemic. Arrhythmia in ACS is common. Careful investigation may lead to further improvement of prognosis. Retrospectively analyzed the year- round data of our center. Study was undertaken to analyze the incidence, frequency and type of arrhythmias in ACS. This is to aid timely intervention and to modify the outcome. Identification of the type of arrhythmia is of therapeutic and prognostic importance.
Methods: This cross sectional analytical study was conducted in the Department of Cardiology, Apollo Hospitals Dhaka, from January 2019 to January 2020 with ACS patients. Enrolled consecutively and data analyzed.
Results: There were 500 patients enrolled considering inclusion and exclusion criteria. Sample was subdivided into 3 groups on the type of ACS. Group-I with UA, Group-II with NSTE - ACS and Group-III with STE - ACS. Different types of arrhythmia noted. Types of arrhythmia were correlated with type of ACS. 500 patients included. Mean age 55.53±12.70, 71.6% male and 28.4% female. 60.4% hypertensive, 46.2% diabetic, 20.2% positive family history of CAD, 32.2% current smoker, 56.4% dyslipidaemic and 9.6% asthmatic. 31.2% UA, 39.2% NSTE-ACS and 29.6% STE-ACS. Type of arrhythmias noted. 22% sinus tachycardia, 20.2% sinus bradycardia, 9% atrial fibrillation, 5.2% ventricular ectopic, 4.8% supra ventricular ectopic, 2.8% bundle branch block, 2.2% atrio-ventricular block, 1% broad complex tachycardia, 0.4% narrow complex tachycardia, 0.2% sinus node dysfunction and 32.2% without any arrhythmia. Significant incidences of arrhythmia detected - respectively 29.8%, 39.2% and 31%, p<0.001.
Conclusions: In conclusion, arrhythmias in ACS are common. More attention should be paid to improve their treatment and prognosis.
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References
Amsterdam EA, Wenger NK, Brindis RG, Casey Jr DE, Ganiats TG, Holmes Jr DR, et al. ACC/AHA guideline for the management of patients with non-ST-elevation acute coronary syndrome: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014;130:e344-e426.
Taylor J. Third universal definition of myocardial infarction. European Heart J. 2012 Oct;33(20):2506.
Enas EA, Dhawan J, Petkar S. Coronary artery diseases in Asian Indians: lessons learnt and the role of lipoprotein a. Indian Heart J. 1996;49:25-34.
Fabijanic D, Culic V, Bozic I, Miric D, Stipic SS, Radic M, et al. Gender differences in in-hospital mortality and mechanisms of death after the first acute myocardial infarction. Ann Saudi Med. 2006;26(6):455-60.
Podrid PJ. Ventricular arrhythmias after acute myocardial infarction, incidence and clinical features. BJMU. 2006;26:1-8.
Kostis JB, Byington R, Friedman LM, Goldstein S, Furberg C, BHAT Study Group. Prognostic significance of ventricular ectopic activity in survivors of acute myocardial infarction. J Am Coll Cardiol. 1987;10:231-42.
Martin TC, Van Longhuyzen H, Bennett B, Peterson S, Beazer C, Thomas CV. The age - specific incidence of admission to the intensive care unit for acute myocardial infarction in Antigua and Barbuda. West Indian Med J. 2007;56(4):326-9.
Svensson AM, Dellborg AM, Abrahamsson P, Karlson T, Herlitz J, Duval SJ, et al. The influence of a history of diabetes on treatment and outcome in acute myocardial infarction, during two periods and in two different countries. Int J Cardiol. 2007;119(3):319-25.
Kokubo Y, Kamide K, Okamura T, Watnabe M, Higashiyama A, Kawanishi K, et al. Impact of high-normal blood pressure on risk of cardiovascular disease in a Japanese urban cohort: the Suita study. Hypertension. 2008;52(4):652-9.
Nagabhushana S, GK RK, Ranganatha M, Virupakshappa V. Study of arrhythmias in acute myocardial infarction. Int J Med Res Rev. 2015;3(7):682-90.
Shah MJ, Bhatt NR, Dabhi A, Thorat PB, Chudasama K, Patel J. A study of 100 cases of arrhythmias in first week of acute myocardial infarction (AMI) in Gujarat: a high risk and previously undocumented population. JCDR. 2014;8(1):58.
Malla RR, Sayami A. In hospital complications and mortality of patients of inferior wall myocardial infarction with right ventricular infarction. JNMA J Nepal Med Assoc. 2007;46(167):99-102.
Crimm A, Severance HW, Coffey K, McKinnis R, Wagner GS, Califf RM. Prognostic significance of isolated sinus tachycardia during first three days of acute myocardial infarction. Am J Med. 1984;76(6):983-8.
Novaro GM, Asher CR, Bhatt DL, Moliterno DJ, Harrington RA, Lincoff AM, et al. Meta-analysis comparing reported frequency of atrial fibrillation after acute coronary syndromes in Asians versus whites. Am J Cardiol. 2008;101(4):506-9.
Majumder AA, Malik A, Zafar A. Conduction disturbances in acute myocardial infarction: incidence, site-wise relationship and the influence on in-hospital prognosis. Bangladesh Med Res Counc Bull. 1996;22(2):74-80.
Perron AD, Sweeney T. Arrhythmic complications of acute coronary syndromes. Emerg Med Clin North Am. 2005;23(4):1065-82.
Pop T, Erbel R, Treese N, von Olshausen K, Meyer J. Incidence and kind of reperfusion arrhythmias in thrombolytic therapy of acute myocardial infarct. Z Kardiol. 1987;76(2):81-5.
Tatli E, Alicik G, Buturak A, Yilmaztepe M, Aktoz M. Arrhythmias following revascularization procedures in the course of acute myocardial infarction: are they indicators of reperfusion or ongoing ischemia? Scient World J. 2013;2013:e160380.